Interspecific sequence comparison of the muscle-myosin heavy-chain genes from Drosophila hydei and Drosophila melanogaster

1994 ◽  
Vol 39 (4) ◽  
pp. 357-368 ◽  
Author(s):  
Koos Miedema ◽  
Harry Harhangi ◽  
Stef Mentzel ◽  
Monique Wilbrink ◽  
Anna Akhmanova ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Sequence Comparison ◽  
Drosophila Hydei ◽  
Myosin Heavy Chain Genes ◽  
Muscle Myosin

scholarly journals Differential expression of non-muscle myosin heavy chain genes during Xenopus embryogenesis

1998 ◽  
Vol 78 (1-2) ◽  
pp. 33-36 ◽  
Author(s):  
Naina Bhatia-Dey ◽  
Masanori Taira ◽  
Mary Anne Conti ◽  
Humaira Nooruddin ◽  
Robert S Adelstein
Keyword(s):  
Myosin Heavy Chain ◽  
Differential Expression ◽  
Heavy Chain ◽  
Myosin Heavy Chain Genes ◽  
Muscle Myosin

scholarly journals Recovery of dominant, autosomal flightless mutants of Drosophila melanogaster and identification of a new gene required for normal muscle structure and function.

Genetics ◽  
1994 ◽  
Vol 137 (1) ◽  
pp. 151-164 ◽  
Author(s):  
R M Cripps ◽  
E Ball ◽  
M Stark ◽  
A Lawn ◽  
J C Sparrow
Keyword(s):  
Drosophila Melanogaster ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Chain Gene ◽  
Normal Muscle ◽  
Muscle Structure ◽  
New Gene ◽  
Flight Muscles ◽  
And Function ◽  
Muscle Myosin

Abstract To identify further mutations affecting muscle function and development in Drosophila melanogaster we recovered 22 autosomal dominant flightless mutations. From these we have isolated eight viable and lethal alleles of the muscle myosin heavy chain gene, and seven viable alleles of the indirect flight muscle (IFM)-specific Act88F actin gene. The Mhc mutations display a variety of phenotypic effects, ranging from reductions in myosin heavy chain content in the indirect flight muscles only, to reductions in the levels of this protein in other muscles. The Act88F mutations range from those which produce no stable actin and have severely abnormal myofibrillar structure, to those which accumulate apparently normal levels of actin in the flight muscles but which still have abnormal myofibrils and fly very poorly. We also recovered two recessive flightless mutants on the third chromosome. The remaining five dominant flightless mutations are all lethal alleles of a gene named lethal(3)Laker. The Laker alleles have been characterized and the gene located in polytene bands 62A10,B1-62B2,4. Laker is a previously unidentified locus which is haplo-insufficient for flight. In addition, adult wild-type heterozygotes and the lethal larval trans-heterozygotes show abnormalities of muscle structure indicating that the Laker gene product is an important component of muscle.

scholarly journals Transcriptional regulation of the Drosophila melanogaster muscle myosin heavy-chain gene

2007 ◽  
Vol 7 (4) ◽  
pp. 413-422 ◽  
Author(s):  
Norbert K. Hess ◽  
Phillip A. Singer ◽  
Kien Trinh ◽  
Massoud Nikkhoy ◽  
Sanford I. Bernstein
Keyword(s):  
Drosophila Melanogaster ◽  
Transcriptional Regulation ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Chain Gene ◽  
Heavy Chain Gene ◽  
Myosin Heavy Chain Gene ◽  
Muscle Myosin
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