The influence of the route of antigen administration on the development of specific antibody-producing cells in the follicles of the popliteal lymph nodes of rabbits

1985 ◽  
Vol 239 (3) ◽  
pp. 657-660 ◽  
Author(s):  
N. van Rooijen ◽  
R. van Nieuwmegen ◽  
N. Kors
Keyword(s):  
Lymph Nodes ◽  
Specific Antibody ◽  
Popliteal Lymph Nodes

scholarly journals LOCALIZATION OF THE ANTIGEN IN POPLITEAL LYMPH NODES OF RABBITS DURING THE FORMATION OF ANTIBODIES TO HORSERADISH PEROXIDASE

1970 ◽  
Vol 18 (2) ◽  
pp. 131-142 ◽  
Author(s):  
WERNER STRAUS
Keyword(s):  
Horseradish Peroxidase ◽  
Lymph Nodes ◽  
Specific Antibody ◽  
Plasma Cells ◽  
Repeated Injection ◽  
Before And After ◽  
Reticular Cells ◽  
Popliteal Lymph Nodes ◽  
Tissue Material

The localization of an antigen (horseradish peroxidase) in popliteal lymph nodes of rabbits was investigated in order to detect the possible interrelationship with the location of the specific antibody in the same tissue material. Staining procedures for peroxidase with benzidine, diaminobenzidine and 3-amino-9-ethyl-carbazole, as well as double staining procedures for the antigen and the antibody and for the antigen (or antibody) and acid phosphatase, were applied before and after adsorption of the antigen to sites of antibody in vitro. The appearance of the antigen in the cells lining the lymph sinuses, in reticular cells of medullary cords, in macrophages and in the "intercellular web" of lymphoid follicles was studied after a single and repeated injection of peroxidase, and the persistence of the antigen at these sites was observed. It was found that the localization of the antigen in the cortex and medulla of the lymph node was different depending on whether or not specific antibodies were present in the blood at the time of injection, and that at certain periods a considerable number of plasma cells and lymphoblasts contained the antigen together with the specific antibody.

scholarly journals LOCATION OF ANTIBODY TO HORSERADISH PEROXIDASE IN POPLITEAL LYMPH NODES OF RABBITS DURING THE PRIMARY AND EARLY SECONDARY RESPONSE

1970 ◽  
Vol 18 (2) ◽  
pp. 120-130 ◽  
Author(s):  
WERNER STRAUS
Keyword(s):  
Horseradish Peroxidase ◽  
Lymph Nodes ◽  
Specific Antibody ◽  
Plasma Cells ◽  
Secondary Response ◽  
Double Staining ◽  
Intercellular Spaces ◽  
Reticular Cells ◽  
Popliteal Lymph Nodes ◽  
Medullary Cords

After a primary injection of horseradish peroxidase into the footpads of rabbits, the specific antibody reaction in popliteal lymph nodes was first seen in plasma cells of medullary cords and, later, in lymphoblasts of germinal centers in the cortex. During the late primary or early secondary response, the reaction also became positive in reticular cells and lymphocytes. Specific antibodies were also present in the intercellular spaces between lymphocytes (reticulum) in the lymphoid follicles and in globules distributed throughout the lymph node. Two weeks following a primary injection of the antigen, many plasma cells containing the specific antibody were located in proximity of macrophages and reticular cells. The phagolysosomes of many macrophages and reticular cells became antibody-positive at about the same time. Double staining procedures were developed by which the antigen and antibody and the antigen or antibody and acid phosphatase (lysosomes) could be visualized in the same tissue section.

scholarly journals The Role of Popliteal Lymph Nodes in Differentiating Rheumatoid Arthritis from Osteoarthritis by Using CE 3D-FSPGR MR Imaging: Relationship of the Inflamed Synovial Volume

2005 ◽  
Vol 6 (2) ◽  
pp. 117 ◽  
Author(s):  
Yong-Min Huh ◽  
Sungjun Kim ◽  
Jin-Suck Suh ◽  
Ho-Taek Song ◽  
Kijun Song ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Mr Imaging ◽  
Lymph Nodes ◽  
Popliteal Lymph Nodes ◽  
Relationship Of

scholarly journals Sex Differences in Mouse Popliteal Lymph Nodes

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Riva Dill-Garlow ◽  
KuanHui Ethan Chen ◽  
Ameae M. Walker
Keyword(s):  
Sex Differences ◽  
Lymph Nodes ◽  
Popliteal Lymph Nodes

Immunoglobulin isotype influences traffic of B lymphocytes through popliteal lymph nodes in sheep

1988 ◽  
Vol 66 (1) ◽  
pp. 79-81
Author(s):  
RL Kerlin ◽  
DL Watson
Keyword(s):  
Lymph Nodes ◽  
B Lymphocytes ◽  
Immunoglobulin Isotype ◽  
Popliteal Lymph Nodes

Popliteal lymph nodes in patients with osteosarcoma: are they metastatic?

2020 ◽  
Vol 49 (11) ◽  
pp. 1807-1817 ◽  
Author(s):  
Mark X. Cleary ◽  
Laura M. Fayad ◽  
Shivani Ahlawat
Keyword(s):  
Lymph Nodes ◽  
Popliteal Lymph Nodes

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on liver, thymus and cell proliferation in popliteal lymph nodes after foot pad injection of streptozotocin in rats

Chemosphere ◽  
1992 ◽  
Vol 25 (7-10) ◽  
pp. 1221-1226 ◽  
Author(s):  
Hans-Jürgen Stroh ◽  
Andrej Schmidt ◽  
Maria Korte ◽  
Ralf Stahlmann
Keyword(s):  
Cell Proliferation ◽  
Lymph Nodes ◽  
Popliteal Lymph Nodes ◽  
Tetrachlorodibenzo P Dioxin ◽  
Foot Pad

scholarly journals A STUDY OF THE RELATION OF TREPONEMA PALLIDUM TO LYMPHOID TISSUES IN EXPERIMENTAL SYPHILIS

1922 ◽  
Vol 35 (1) ◽  
pp. 39-62 ◽  
Author(s):  
Louise Pearce ◽  
Wade H. Brown
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Lymphoid Tissue ◽  
Practical Importance ◽  
Treponema Pallidum ◽  
Serial Passage ◽  
Point Of View ◽  
Lymphoid Tissues ◽  
Skin Nodule ◽  
Popliteal Lymph Nodes

A widespread dissemination of Treponema pallidum from a local focus of inoculation in the rabbit constantly occurs by way of the lymphatics. Spirochetes were regularly recovered from the satellite lymph nodes by animal inoculation after scrotal inoculation; they were present as early as 2 days, when no specific primary reaction was detected, and at later periods of from 5 to 61 days after inoculation. Other superficial nodes at remote sites such as the popliteals and with no syphilitic lesions in the drainage area have also been shown to harbor active organisms. Although spirochetes were found in relatively few of the lymph node emulsions, the orchitis resulting from their injection was of a rapidly progressive type with an incubation period but slightly longer than that produced by a testicular or skin nodule emulsion rich in spirochetes. It has further been shown that a syphilitic infection is sufficiently established in the rabbit body within 48 hours after scrotal inoculation so that the primary lesion is no longer essential for its maintenance. Active treponemata survive in the popliteal lymph nodes for long periods of time and have been regularly recovered from them in cases of true latency. The lymph nodes, therefore, function as reservoirs of the organisms. The ability to recover the spirochetes from lymphoid tissue through successive generations is seen in the serial passage of lymph node emulsion to testicle during an 18 months period. The persistence of spirochetes in lymphoid tissue irrespective of the presence or absence of syphilitic lesions is a characteristic and fundamental feature of syphilis of the rabbit. The existence of infection, therefore, may be demonstrated at any time by the recovery of spirochetes from the popliteal lymph nodes by animal inoculation. This fact is of great practical importance in the therapy of the infection and may be profitably utilized in determining the ultimate effect of a therapeutic agent. These experiments demonstrate that the disease is not confined to the site of local inoculation but that lymphogenous dissemination of treponemata regularly takes place, and that during the course of this process organisms become localized in the lymph nodes and exist there indefinitely irrespective of the occurrence of manifestations of disease. The intimate relation of Treponema pallidum to lymphoid tissue is an essential concept of syphilis of the rabbit, and from this point of view, the infection is primarily one of lymphoid tissue.

Detection of the Maedi Visna Virus in the popliteal lymph nodes of sheep infected by the respiratory route

2009 ◽  
Vol 33 (S1) ◽  
pp. 153-155 ◽  
Author(s):  
S. Preziuso ◽  
G. E. Magi ◽  
C. Valente ◽  
V. Cuteri
Keyword(s):  
Lymph Nodes ◽  
Visna Virus ◽  
Maedi Visna Virus ◽  
Popliteal Lymph Nodes

Translocation Kinetics of Plutonium Oxide from the Popliteal Lymph Nodes of Beagles

1975 ◽  
Vol 28 (4) ◽  
pp. 395-398 ◽  
Author(s):  
Gerald E. Dagle ◽  
Jacques L. Lebel ◽  
Robert D. Phemister ◽  
Robert L. Watters ◽  
Leo S. Gomez
Keyword(s):  
Lymph Nodes ◽  
Popliteal Lymph Nodes ◽  
Kinetics Of
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