Validation of a new closed circuit indirect calorimetry method compared with the open Douglas bag method

1989 ◽  
Vol 15 (4) ◽  
pp. 274-278 ◽  
Author(s):  
J. M. Raurich ◽  
J. Ibañez ◽  
P. Marse
Keyword(s):  
Indirect Calorimetry ◽  
Closed Circuit ◽  
Douglas Bag ◽  
Douglas Bag Method

Measurement of metabolic rate in hyperoxia

1981 ◽  
Vol 51 (3) ◽  
pp. 725-731 ◽  
Author(s):  
H. G. Welch ◽  
P. K. Pedersen
Keyword(s):  
Metabolic Rate ◽  
Submaximal Exercise ◽  
Co2 Production ◽  
O2 Uptake ◽  
Vo2 Max ◽  
Conventional Calculation ◽  
Mixing Chamber ◽  
Douglas Bag ◽  
Douglas Bag Method ◽  
Fick Equation

The conventional Douglas bag calculation for estimating O2 uptake (VO2) during exercise in normoxia and hyperoxia, VO2 = VE . (FIO2 . FEN2/FIN2 - FEO2), was tested against two other valid calculations: the Fick equation, VO2 = VI . FIO2 - VE . FEO2, and the equation VO2 = VI - VE - VCO2 (VE and VI are expired and inspired ventilation, respectively; FEO2 and FIO2 are expired and inspired O2 contents, respectively; FEN2 and FIN2 are expired and inspired N2 contents, respectively; and VCO2 is CO2 production.). These calculations are based on different assumptions, in part, and are affected to a varying degree of errors in volume or gas fraction measurements. With the conventional Douglas bag technique, we found evidence of an overestimate of VO2 during hyperoxia. After the introduction of a mixing chamber for sampling expired air, the means of the three methods were not significantly different. The variability among the methods was least with the conventional calculation but increased with higher O2 fractions. The average VO2 for submaximal exercise in hyperoxia was not significantly different from that of normoxia. VO2 max was significantly higher in hyperoxia. The increased variability of the Douglas bag method in hyperoxia may lead to overestimates of VO2 max unless special precautions are taken.

scholarly journals Validation of a wearable metabolic tracker (Breezing ProTM) for Resting Energy Expenditure (REE) measurement via Douglas bag method

2020 ◽  
Vol 7 (1) ◽  
pp. 001-008
Author(s):  
Mora S Jimena ◽  
Mann Stewart ◽  
Bridgeman Devon ◽  
Quach Ashley ◽  
Balsells Liliana ◽  
...  
Keyword(s):  
Energy Expenditure ◽  
Resting Energy Expenditure ◽  
Douglas Bag ◽  
Douglas Bag Method ◽  
Resting Energy

Gas Exchange During Ventilator Treatment: a Validation of a Computerized Technique and its Comparison With the Douglas Bag Method

1984 ◽  
Vol 28 (4) ◽  
pp. 462-468 ◽  
Author(s):  
S. Bredbagka ◽  
S. Kawachi ◽  
O. Norlander ◽  
B. Kirk
Keyword(s):  
Gas Exchange ◽  
Douglas Bag ◽  
Douglas Bag Method

Evaluation of the Oxycon Mobile metabolic system against the Douglas bag method

2009 ◽  
Vol 109 (2) ◽  
pp. 159-171 ◽  
Author(s):  
Hans Rosdahl ◽  
Lennart Gullstrand ◽  
Jane Salier-Eriksson ◽  
Patrik Johansson ◽  
Peter Schantz
Keyword(s):  
Metabolic System ◽  
Douglas Bag ◽  
Douglas Bag Method

Comparison of two methods, the thermodilution method of Fick and the Douglas bag method, in estimating the resting energy expenditure (REE)

1995 ◽  
Vol 15 (12) ◽  
pp. 1747-1754 ◽  
Author(s):  
M. Bizani ◽  
K. Koletsos ◽  
D. Matamis ◽  
D. Lagonidis ◽  
N. Gerogianni ◽  
...  
Keyword(s):  
Energy Expenditure ◽  
Resting Energy Expenditure ◽  
Thermodilution Method ◽  
Douglas Bag ◽  
Douglas Bag Method ◽  
Resting Energy

Abstract 279: Cardiac Arrest is Associated With a Global Level Alteration in Oxygen Metabolism: A Clinical Pilot Study

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Koichiro Shinozaki ◽  
Kota Saeki ◽  
Qiuping Zhou ◽  
Hugh Cassiere ◽  
Lee Jacobson ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Healthy Volunteers ◽  
Oxygen Metabolism ◽  
Surgical Patients ◽  
Surgical Patient ◽  
Global Level ◽  
Mechanically Ventilated ◽  
Metabolic Alteration ◽  
Douglas Bag ◽  
Douglas Bag Method

Objective: We recently reported that a global-level metabolic alteration occurs after cardiac arrest (CA) in our high fidelity rodent model. The finding was that dissociation of O 2 consumption (VO 2 ) and carbon dioxide generation (VCO 2 ) resulted in a respiratory quotient (RQ: calculated by dividing VCO 2 by VO 2 ) that fell well outside the normally cited range of 0.7-1.0. We hypothesized that a lowered RQ is similarly found in human CA patients. Methods: The study consisted of three subject groups: 1) healthy volunteer, 2) post-surgical patient (control) and 3) post-CA patient. We measured the VO 2 and VCO 2 of mechanically ventilated subjects using the Douglas bag method. Inspiration and expiration gas samples were collected in two separate bags . and RQ was calculated from CO 2 and O 2 gas concentrations in the samples. The patients and healthy volunteers were ventilated using the same model mechanical ventilator. Alert healthy volunteers bit onto a mouthpiece and the samples were collected, while post-surgical and post-CA patients were unconscious during the measurements. We measured the RQ of healthy volunteers at normal and high fractions of inspired oxygen (FIO 2 ) in order to test the validity of our methods at various inspired O 2 levels. Results: The RQs of the three healthy volunteers were 0.83, 0.92 and 0.85 at an FIO 2 of 0.21 and 0.86, 0.88, and 0.83 at an FIO 2 of 0.90 respectively. The RQs of the two post-surgical patients were 0.92 and 0.88 at an FIO 2 of 0.5. None of the post-surgical patients had any complications following the surgery and all were discharged. The RQ of a post-CA patient measured 2.5 hours after the CA was found to be 0.72 at an FIO 2 of 0.9. The CA patient expired within 24 hours of hospital admission. Conclusions: The same trend between the findings of both our rodent study and the CA patient suggest that resuscitation from CA alters cellular metabolism on a global level. This metabolic alteration in turn causes the dissociation of O 2 consumption and CO 2 generation resulting in a lowered RQ. Our findings warrant a larger clinical study to confirm a lowered RQ in post-CA patients and bench work to elucidate the causative mechanism of this relationship.

Examination of the Moxus Modular Metabolic System by the Douglas-bag technique

2012 ◽  
Vol 37 (5) ◽  
pp. 860-871 ◽  
Author(s):  
Jon Ingulf Medbø ◽  
Asgeir Mamen ◽  
Fernando G. Beltrami
Keyword(s):  
Respiratory Exchange Ratio ◽  
Computer Software ◽  
Metabolic System ◽  
Trained Subjects ◽  
Residual Variation ◽  
Douglas Bag ◽  
Douglas Bag Method ◽  
Software And Hardware ◽  
R Value ◽  
Moxus Modular Metabolic System

The purpose of this study was to examine the performance of the Moxus Modular Metabolic System from AEI Technologies, Inc. using the Douglas-bag method as reference. To achieve this, eight moderately trained subjects cycled for 5 min at constant powers from 50 to 300 W in increments of 50 W. The O2 uptake was measured simultaneously by both systems during the last minute of each stage. The O2 uptake reported by the Moxus system was 83 ± 78 mL·min–1 higher (mean ± SD; ≈3%, +62 µmol·s–1, P < 0.001) than that reported by the Douglas-bag method; the bias varied by ≈2% between the subjects. The higher O2 uptake of the Moxus system was a consequence of 1.4% ± 3.0% higher reported ventilation and 2% ± 3% higher reported O2 extraction per volume of air breathed. The respiratory exchange ratio (R value) reported by the Moxus system rose proportionally to that of the Douglas-bag method and was 1% ± 2% higher for the range examined (0.75–1.10). Repeated tests of the maximal O2 uptake showed a variability (coefficient of variation) of 2.5%. The study concluded that measurements by the Moxus system showed some bias and residual variation and, in addition, some systematic differences between the subjects in the O2 uptake. The R value was reported quite accurately with moderate random error. Although there were some computer software and hardware instability problems that need to be solved, the Moxus system worked quite well and provided data more reliable than those of most commercial instruments.

The Ventilation-Corrected ParvoMedics TrueOne 2400 Provides a Valid and Reliable Assessment of Resting Metabolic Rate (RMR) in Athletes Compared With the Douglas Bag Method

2016 ◽  
Vol 26 (5) ◽  
pp. 454-463 ◽  
Author(s):  
Amy L. Woods ◽  
Laura A. Garvican-Lewis ◽  
Anthony J. Rice ◽  
Kevin G. Thompson
Keyword(s):  
Metabolic Rate ◽  
Resting Metabolic Rate ◽  
Regression Equation ◽  
Reliable Measurement ◽  
Metabolic Cart ◽  
Typical Error ◽  
Reliable Assessment ◽  
Douglas Bag ◽  
Douglas Bag Method ◽  
The Difference

The aim of the current study was to determine if a single ParvoMedics TrueOne 2400 metabolic cart provides valid and reliable measurement of RMR in comparison with the criterion Douglas Bag method (DB). Ten endurance-trained participants completed duplicate RMR measurements on 2 consecutive days using the ParvoMedics system in exercise mode, with the same expirate analyzed using DB. Typical error (TE) in mean RMR between the systems was 578.9 kJ or 7.5% (p = .01). In comparison with DB, the ParvoMedics system over-estimated RMR by 946.7 ± 818.6 kJ. The bias between systems resulted from ParvoMedics VE(STPD) values. A regression equation was developed to correct the bias, which reduced the difference to -83.3 ± 631.9 kJ. TE for the corrected ParvoMedics data were 446.8 kJ or 7.2% (p = .70). On Day 1, intraday reliability in mean RMR for DB was 286.8 kJ or 4.3%, (p = .54) and for ParvoMedicsuncorrected, 359.3 kJ or 4.4%, (p = .35), with closer agreement observed on Day 2. Interday reliability for DB was 455.3 kJ or 6.6% (p = .61) and for ParvoMedicsuncorrected, 390.2 kJ or 6.3% (p = .54). Similar intraday and interday TE was observed between ParvoMedicsuncorrected and ParvoMedicscorrected data. The ParvoMedics TrueOne 2400 provided valid and reliable RMR values compared with DB when the VE(STPD) error was corrected. This will enable widespread monitoring of RMR using the ParvoMedics system in a range of field-based settings when DB is not available.

Nitrogen narcosis attenuates shivering thermogenesis

1995 ◽  
Vol 78 (6) ◽  
pp. 2241-2244 ◽  
Author(s):  
I. B. Mekjavic ◽  
S. A. Savic ◽  
O. Eiken
Keyword(s):  
Oxygen Uptake ◽  
Healthy Subjects ◽  
Thermal Perception ◽  
Hyperbaric Chamber ◽  
Nitrogen Narcosis ◽  
Douglas Bag ◽  
Douglas Bag Method ◽  
Core Cooling ◽  
Oxygen Uptake Response ◽  
Shivering Thermogenesis

Thermoregulatory responses of eight healthy subjects (six men and two women) were compared when they were head-out immersed in 15 degrees C water at both 1 and 6 ATA. Both trials were conducted in a hyperbaric chamber. During the immersions, esophageal temperature (T(es)) and skin temperature at two sites (chest and calf) were recorded at minute intervals. Oxygen uptake was determined at 5-min intervals with the Douglas bag method. The order of the two trials was alternated. The rate of T(es) cooling was greater during the 6-ATA trial [2.1 +/- 0.5 degrees C/h (SE)] than during the 1-ATA trial (1.3 +/- 0.5 degrees C/h; P < 0.01). Despite the greater rate of core cooling, and presumably a greater thermal drive for shivering, the oxygen uptake response for a similar decrement in T(es) was lower during exposure to 6 than to 1 ATA (P < 0.05). Also, for similar displacement in T(es), the subjects perceived the immersions at 6 ATA to be less cold than those at 1 ATA (P < 0.05). It is concluded that the development of hypothermia in compressed-air divers may be due, in large part, to the attenuation of heat production and cold perception. Most likely, the observed effects on the autonomic responses and thermal perception are due to an inhibitory action of hyperbaric nitrogen on central neural structures involved in temperature regulation.

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