Ultrastructural morphometric study on the rat heart after chronic ethanol feeding

1980 ◽  
Vol 389 (1) ◽  
pp. 59-77 ◽  
Author(s):  
Gerhard Mall ◽  
Torsten Mattfeldt ◽  
Benedikt Volk
Keyword(s):  
Rat Heart ◽  
Chronic Ethanol ◽  
Morphometric Study ◽  
Ethanol Feeding

Effect of Chronic Ethanol Feeding on Oxysterols in Rat Liver

2002 ◽  
Vol 36 (6) ◽  
pp. 661-666 ◽  
Author(s):  
Koichi Ariyoshi ◽  
Junko Adachi ◽  
Migiwa Asano ◽  
Yasuhiro Ueno ◽  
Rajkumar Rajendram ◽  
...  
Keyword(s):  
Rat Liver ◽  
Chronic Ethanol ◽  
Ethanol Feeding

Rat mitochondrial ATP synthase ATP5G3: cloning and upregulation in pancreas after chronic ethanol feeding

2001 ◽  
Vol 6 (2) ◽  
pp. 91-98 ◽  
Author(s):  
HA-SHENG LI ◽  
JI-YING ZHANG ◽  
BRYAN S. THOMPSON ◽  
XIAO-YING DENG ◽  
MICHAEL E. FORD ◽  
...  
Keyword(s):  
Atp Synthase ◽  
Cellular Response ◽  
Molecular Mechanisms ◽  
Metabolic Stress ◽  
Nuclear Gene ◽  
Chronic Ethanol ◽  
Ethanol Ingestion ◽  
Pancreatic Acinar Cells ◽  
Mitochondrial Atp Synthase ◽  
Ethanol Feeding

Individuals with chronic excessive alcohol ingestion are put at the risk of acute and chronic pancreatitis. Underlying molecular mechanisms are unknown. Differential gene expression in the pancreas was profiled using mRNA differential display by comparison between control and ethanol-consuming rats. Male Wistar rats were fed with diets containing 6.7% (vol/vol) ethanol for 4 wk. A cDNA tag that was overexpressed in the pancreas of rats fed ethanol was isolated. A 723-bp cDNA was cloned from a rat pancreatic cDNA library, which encodes a novel rat mitochondrial ATP synthase subunit 9, isoform 3 (ATP5G3), which is homologous to a human ATP5G3 gene. Real-time PCR demonstrated that all three nuclear gene isoforms (ATP5G1, ATP5G2, and ATP5G3) were consistently upregulated in the pancreas of alcohol-consuming rats, parallel with mitochondrial injury. The cellular response to mitochondrial damage and metabolic stress may reflect an adaptive process for mitochondrial repair in pancreatic acinar cells during chronic ethanol ingestion.

scholarly journals Increased activity of intestinal microsomal enzymes after chronic ethanol feeding

1978 ◽  
Vol 74 (5) ◽  
pp. 1092 ◽  
Author(s):  
Helmut K. Seitz ◽  
Mark A. Korsten ◽  
Charles S. Lieber
Keyword(s):  
Chronic Ethanol ◽  
Microsomal Enzymes ◽  
Ethanol Feeding ◽  
Increased Activity

Effects of chronic ethanol feeding on glutathione turnover in the rat

1985 ◽  
Vol 34 (9) ◽  
pp. 1559-1563 ◽  
Author(s):  
Sebastian Morton ◽  
Mack C. Mitchell
Keyword(s):  
Chronic Ethanol ◽  
Ethanol Feeding
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