Effect of activation of protein kinase C on excitation-contraction coupling in frog twitch muscle fibres

1994 ◽  
Vol 428 (3-4) ◽  
pp. 224-231 ◽  
Author(s):  
X. F. Wang ◽  
P. H. Zhu
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Muscle Fibres ◽  
Excitation Contraction Coupling ◽  
Contraction Coupling ◽  
Kinase C

Physiological and pharmacological properties of muscle cells isolated from the flatworm Bdelloura candida (Tricladia)

Parasitology ◽  
1994 ◽  
Vol 109 (3) ◽  
pp. 325-335 ◽  
Author(s):  
K. L. Blair ◽  
P. A. V. Anderson
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Voltage Clamp ◽  
Muscle Cells ◽  
Muscle Fibres ◽  
Pharmacological Properties ◽  
Single Muscle ◽  
Kinase C

SummaryA protocol for dissociating single muscle fibres from intact flatworms was developed. Muscle fragments of various sizes were obtained, many with their cell bodies, or myocytons, intact. Many of the fibres were spontaneously contractile, and they and others contracted in response to applications of transmitter candidates, activators of protein kinase C and the anthelmintic praziquantel. The responses were all similar to those evoked in strips of tissue. Voltage clamp recordings from the isolated muscle fibres revealed that they possess an inward Ca2+ current and 3 separate K+ currents. These results indicate that muscle fibres in Bdelloura bear receptors for neurotransmitters and that preparations of dispersed muscle fibres can be used for studying the basic physiological and pharmacological properties of platyhelminth muscle.

Role Of Protein Kinase C In Myogenic Calcium- Contraction Coupling Of Rat Cannulated Mesenteric Small Arteries

2001 ◽  
Vol 28 (10) ◽  
pp. 848-855 ◽  
Author(s):  
Jos Pm Wesselman ◽  
Jos AE Spaan ◽  
Esther T van der Meulen ◽  
Ed VanBavel
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Small Arteries ◽  
Contraction Coupling ◽  
Kinase C
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