Study of the mechanism of isomerization of 2-bromopropyl benzoate using an18O isotopic label

1988 ◽  
Vol 37 (9) ◽  
pp. 1925-1926
Author(s):  
E. D. Gopius ◽  
M. L. Karpyuk ◽  
T. A. Smolina ◽  
O. A. Reutov
Keyword(s):  
Isotopic Label

scholarly journals Stable Deuterium Labeling of Histidine-Rich Lysine-Based Dendrimers

Molecules ◽  
2019 ◽  
Vol 24 (13) ◽  
pp. 2481 ◽  
Author(s):  
Nadezhda N. Sheveleva ◽  
Denis A. Markelov ◽  
Mikhail A. Vovk ◽  
Irina I. Tarasenko ◽  
Mariya E. Mikhailova ◽  
...  
Keyword(s):  
Delivery System ◽  
Hydrogen Isotope ◽  
Isotope Labeling ◽  
Biological Pathways ◽  
Deuterium Labeling ◽  
Isotopic Label ◽  
Peptide Dendrimers ◽  
Reliable Monitoring ◽  
Tremendous Importance ◽  
Low Toxicity

Peptide dendrimers, due to their biocompatibility and low toxicity, are highly promising candidates as nanocarriers for drugs and genes. The development of this kind of delivery system requires reliable monitoring of their metabolic and biological pathways. In this respect, hydrogen isotope labeling has tremendous importance, being a safe tool for detection of the labeled nanocarriers. In this work, we have synthesized new histidine-rich lysine-based dendrimers (Lys-2His dendrimer) with two linear histidine (His) residues in every inner segment. The presence of His residues has enabled us to perform controlled deuteration of Lys-2His dendrimers. The high deuteration degree (around 70%) does not practically change after redissolving the samples in H2O and heating them at 40 °C, which indicates the isotopic label stability.

Rearrangement studies with 14C. XLIII. The acetolysis of trianisyl[2-14C]vinyl bromide

1979 ◽  
Vol 57 (11) ◽  
pp. 1384-1387 ◽  
Author(s):  
Choi Chuck Lee ◽  
Ursula Weber ◽  
Craig A. Obafemi
Keyword(s):  
Starting Material ◽  
Vinyl Bromide ◽  
Isotopic Label ◽  
Relative Contribution

Acetolyses of trianisyl[2-14C]vinyl bromide (1-Br-2-14C) were carried out in the presence of various amounts of added NaOAc or NaOAc and LiBr. Scramblings of the isotopic label from C-2 to C-1 arising from 1,2-anisyl shifts in the trianisylvinyl cation were observed in both the reaction product and the recovered, unconsumed reactant. The results indicate that the relative contribution of the 1,2-shift process is decreased with an increase in the amount of NaOAc or LiBr, in support of a mechanism involving formation of the dissociated trianisylvinyl cation which will competitively undergo 1,2-anisyl shift to give scrambling, be captured by Br− ion and return to scrambled starting material, and be captured by OAc− ion to give scrambled product. The results are also compared with previous data from solvolyses of triphenyl[2-14C]vinyl bromide and the differences are discussed.

Isotopic-label-directed observation of the nuclear Overhauser effect in poorly resolved proton NMR spectra

1985 ◽  
Vol 107 (3) ◽  
pp. 711-712 ◽  
Author(s):  
R. H. Griffey ◽  
M. A. Jarema ◽  
S. Kunz ◽  
P. R. Rosevear ◽  
A. G. Redfield
Keyword(s):  
Nmr Spectra ◽  
Nuclear Overhauser Effect ◽  
Proton Nmr ◽  
Isotopic Label ◽  
Overhauser Effect ◽  
Nuclear Overhauser

scholarly journals Unraveling the Photocatalytic Mechanisms on TiO2 Surfaces Using the Oxygen-18 Isotopic Label Technique

Molecules ◽  
2014 ◽  
Vol 19 (10) ◽  
pp. 16291-16311 ◽  
Author(s):  
Xibin Pang ◽  
Chuncheng Chen ◽  
Hongwei Ji ◽  
Yanke Che ◽  
Wanhong Ma ◽  
...  
Keyword(s):  
Label Technique ◽  
Isotopic Label

Operando spectroscopic and isotopic-label-directed observation of LaN-promoted Ru/ZrH2 catalyst for ammonia synthesis via associative and chemical looping route

2020 ◽  
Vol 389 ◽  
pp. 218-228 ◽  
Author(s):  
Lingling Li ◽  
Tianhua Zhang ◽  
Jihui Cai ◽  
Hongfang Cai ◽  
Jun Ni ◽  
...  
Keyword(s):  
Ammonia Synthesis ◽  
Chemical Looping ◽  
Isotopic Label
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