Clinical presentations of the Tourette syndrome diathesis

Jeffrey Sverd

doi:10.1007/bf01098172

The Clinical Neurology of Tourette Syndrome

CNS Spectrums ◽

10.1017/s1092852900011366 ◽

1999 ◽

Vol 4 (2) ◽

pp. 36-37,49-53 ◽

Cited By ~ 3

Author(s):

Gerald Erenberg

Keyword(s):

Quality Of Life ◽

Differential Diagnosis ◽

Adverse Effects ◽

Tourette Syndrome ◽

Short Duration ◽

Tic Disorders ◽

Pharmacologic Therapy ◽

Clinical Neurology ◽

Clinical Presentations

AbstractTic disorders may manifest in a wide variety of clinical presentations, ranging from single tics of relatively short duration to a series of complex tics that may last for years. An understanding of the etiology of various tic disorders is essential to establish a differential diagnosis of Tourette syndrome (TS). Because TS is incurable, improvement in quality of life is the primary goal of pharmacologic therapy. Although neuroleptics have been the most effective medications to date in managing the symptoms of TS, they may have significant adverse effects that limit their use. Several alternative pharmacologic options are either available or under investigation.

Download Full-text

Impairment Tutorial: Functionally Limiting Upper Extremity Pain: Controversies in Impairment Rating

Guides Newsletter ◽

10.1001/amaguidesnewsletters.2003.sepoct02 ◽

2003 ◽

Vol 8 (5) ◽

pp. 4-12

Author(s):

Lorne Direnfeld ◽

James Talmage ◽

Christopher Brigham

Keyword(s):

Upper Extremity ◽

Radicular Pain ◽

Illness Behavior ◽

Orthopedic Surgeon ◽

First Case ◽

Clinical Presentations ◽

Whole Person ◽

Physical Examinations ◽

Upper Extremity Impairment ◽

The Individual

Abstract This article was prompted by the submission of two challenging cases that exemplify the decision processes involved in using the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides). In both cases, the physical examinations were normal with no evidence of illness behavior, but, based on their histories and clinical presentations, the patients reported credible symptoms attributable to specific significant injuries. The dilemma for evaluators was whether to adhere to the AMA Guides, as written, or to attempt to rate impairment in these rare cases. In the first case, the evaluating neurologist used alternative approaches to define impairment based on the presence of thoracic outlet syndrome and upper extremity pain, as if there were a nerve injury. An orthopedic surgeon who evaluated the case did not base impairment on pain and used the upper extremity chapters in the AMA Guides. The impairment ratings determined using either the nervous system or upper extremity chapters of the AMA Guides resulted in almost the same rating (9% vs 8% upper extremity impairment), and either value converted to 5% whole person permanent impairment. In the second case, the neurologist evaluated the individual for neuropathic pain (9% WPI), and the orthopedic surgeon rated the patient as Diagnosis-related estimates Cervical Category II for nonverifiable radicular pain (5% to 8% WPI).

Download Full-text

Clinical presentations and hemodynamic patterns in subclavian steal S. Cencetti, S. Bacalli, A. Montigiani, A. Caneschi, L. Colzi, A.M. Buccheri, A. Lagi. Stroke Unit, General Medicine Department, S.Maria Nuova Hospital. Firenze, Italy

European Journal of Ultrasound ◽

10.1016/s0929-8266(97)90054-9 ◽

1997 ◽

Vol 5 ◽

pp. 22

Keyword(s):

Stroke Unit ◽

General Medicine ◽

Medicine Department ◽

Subclavian Steal ◽

Clinical Presentations

Download Full-text

Social Cognition in Gilles de la Tourette Syndrome

Zeitschrift für Neuropsychologie ◽

10.1024/1016-264x/a000272 ◽

2019 ◽

Vol 30 (4) ◽

pp. 243-249

Author(s):

Ronja Weiblen ◽

Melanie Jonas ◽

Sören Krach ◽

Ulrike M. Krämer

Keyword(s):

Tourette Syndrome ◽

Social Cognitive ◽

Mirror Neuron System ◽

Mirror Neuron ◽

Theoretical Work ◽

Neural Processes ◽

The Social ◽

Decision Making System ◽

Social Decision Making ◽

Work Done

Abstract. Research on the neural mechanisms underlying Gilles de la Tourette syndrome (GTS) has mostly concentrated on abnormalities in basal ganglia circuits. Recent alternative accounts, however, focused more on social and affective aspects. Individuals with GTS show peculiarities in their social and affective domain, including echophenomena, coprolalia, and nonobscene socially inappropriate behavior. This article reviews the experimental and theoretical work done on the social symptoms of GTS. We discuss the role of different social cognitive and affective functions and associated brain networks, namely, the social-decision-making system, theory-of-mind functions, and the so-called “mirror-neuron” system. Although GTS affects social interactions in many ways, and although the syndrome includes aberrant social behavior, the underlying cognitive, affective, and neural processes remain to be investigated.

Download Full-text