Clinical presentations and hemodynamic patterns in subclavian steal S. Cencetti, S. Bacalli, A. Montigiani, A. Caneschi, L. Colzi, A.M. Buccheri, A. Lagi. Stroke Unit, General Medicine Department, S.Maria Nuova Hospital. Firenze, Italy

1997 ◽  
Vol 5 ◽  
pp. 22
Author(s):  
Sadhna Sharma ◽  
Hari Babu Ramineni ◽  
K. Poornima Shahitha ◽  
K. Mounika ◽  
P. Ramyachandra ◽  
...  

Background: Renal impairment is the primary cause of mortality and morbid conditions in patients. Inappropriate drug use in patients who are with risk of renal damage causes harmful and deleterious effects. Adjusting doses based on renal function is necessary for renal risk drugs, primarily to avoid adverse reactions of medications. Aim of the present study was to assess the risk of incidence on ADRs with drugs lowering the renal function.Methods: This is a cross-sectional observational study conducted in General Medicine department. 230 Patients constituted the sample in the study. The study was conducted for a period of one year and prescriptions with renal risk drugs were evaluated. Changes in the renal functional tests were compared to the normal range and adverse drug responses were monitored.Results: A total of 230 patients who fulfilled the inclusion criteria were included in the study. The meanage of the study subjects were 50.9±15.2 respectively. 56.39% patients were men and 43.6% were women. Renal risk drugs included in the study are anti-hypertensive, antibiotics, and analgesics. Paracetamol (24.77%) followed by telmisartan (20.85%) are the predominantly prescribed renal risk drugs with high incidence of adverse drug reactions. Causality assessment by Naranjo ADR probability scale showed out of 211 ADRs, 51.6% were possible, 25.59% were doubtful, 21.8% were probable and 0.94% was definite.Conclusions: The current study signifies that patients under high risk of renal damage require continuous monitoring and optimized therapy for better disease management.


2021 ◽  
Vol 9 (02) ◽  
pp. 136-143
Author(s):  
Gyana Deepa.T ◽  
◽  
Vaishnavi V. ◽  
Sahithi V. Pharm D. ◽  
CH. Sridevi ◽  
...  

Back ground: Cerebro Vascular Accident is a rapidly developing signs of focal disturbances which lasts for more than 24hours and is divided into 3 types- Ischemic stroke, Hemorrhagic stroke, Transient ischemic stroke. Objective: To assess drug treatment pattern of anti-platelets, the involvement of clinical pharmacist to improve the patient outcome, the risk factors of stroke and monitor the risk of anti-platelets. Methods and methodology: A hospital based prospective observational study is conducted in neurology and general medicine department for 6 months meeting the inclusion criteria by obtaining information from the case sheets, laboratory reports and on an interview with the patient. Discussion: Among 80 patients, most of the cases reported were from the age group of 51-60yrs and males were more prone to stroke. Ischemic stroke is seen majorly and strokes are mostly diagnosed with MRI,CT scan, ECG and were treated with Aspirin and Atorvastatin (symptomatic treatment). Conclusion: Stroke (Cerebro Vascular Accident) is the second leading cause of death. Major risk factors of stroke include hypertension and diabetes mellitus. Prevention of these diseases can prevent stroke. People with these diseases are risk factors to stroke.With lifestyle modifications and medication adherence can reduce the risk of stroke. According to the study, majority of patients were males, people who smoke and consume alcohol are also prone to stroke. In this study, we dealt with the risk factors of stroke and its treatment options and lifestyle modifications which can prevent the risk of stroke.


Author(s):  
Shereen Hassan ◽  
U. Ujwal Kumar ◽  
Venessa Mascarenhas ◽  
G. Suresh ◽  
K. C. Bharath Raj ◽  
...  

The present study was carried out to determine the incidence of Adverse Drug Reactions (ADRs) in general medicine department and to assess and analyze the causality, severity, and preventability of ADRs. A prospective observational study was conducted in the general medicine department for six months. All patients receiving drug therapy are considered and are selected based on the inclusion criteria. Patient demographic details like age, gender, diagnosis, past medical history, concomitant medications, etc., are recorded from the patient data gathering form. The causality assessment is accomplished using Naranjo and WHO scales. The severity is carried out using the Modified Hartwig and Siegel scale. The preventability evaluation is accomplished using the Modified Schmock and Thornton scale. The study included 385 patients were between the age group of 18 years and, out of which 34 patients developed adverse drug effects including female and male. Patients between the age group of 40-50 years (18.1%) developed a high incidence of ADRs. The causality was assessed using Naranjo’s causality assessment scale, 44.1% reactions were probable; 29.4% reactions were certain, 23.5% reactions were possible and 2.9 % reactions were conditional. When the reactions were assessed most of them were assessed 55.1% were moderate and 61.8% were probably preventable. Appropriate observation of the drug effect is essential to ensure the safety of the patient. This also will have the advantage of reducing the incidence of the ADRs, thus deplete the complications and helps to improve the quality of life of the patients.


1979 ◽  
Vol 18 (03) ◽  
pp. 138-145 ◽  
Author(s):  
S. Certttti ◽  
E. Longbxni ◽  
F. Pinciholi

The problem of the comprehensive organization of the medical record is discussed in this paper. The basis of the organizational scheme is the integration of both fixed-text and free-text components with constraints imposed upon the original formatting of the free text. To support the diagnostic procedure a component of the record is a »diagnosis sheet«, which embodies a differential diagnosis approach and is discussed in detail.Results of more than two years of practical experience in the general medicine department of a regional hospital in Italy are presented. A trend towards a standardization of the medical terminology used was noted. Physicians' acceptance of a more rational conception of the medical record was high and a considerable flexibility in the language employed was observed. Finally, it is important to note that this new approach to the organization of the medical record was conceived in such a way as to make it processable by a computer located within the department itself. The initial experiences with the computerization of the record are presented and discussed with a view to future implementations and implications for cooperative, multidisciplinary research in medicine and information science.


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