scholarly journals Volumetric bone mineral density using peripheral quantitative computed tomography in Japanese women

1997 ◽  
Vol 7 (3) ◽  
pp. 195-199 ◽  
Author(s):  
Y. Hasegawa ◽  
K. Kushida ◽  
K. Yamazaki ◽  
T. Inoue
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Peripheral Quantitative Computed Tomography ◽  
Japanese Women ◽  
Volumetric Bone Mineral Density ◽  
Mineral Density

Effect of Rheumatoid Arthritis on Volumetric Bone Mineral Density and Bone Geometry, Assessed by Peripheral Quantitative Computed Tomography in Postmenopausal Women Treated with Bisphosphonates

2012 ◽  
Vol 39 (6) ◽  
pp. 1215-1220 ◽  
Author(s):  
SYMEON TOURNIS ◽  
VASILIOS SAMDANIS ◽  
SAVAS PSARELIS ◽  
CHRYSA LIAKOU ◽  
JULIA ANTONIOU ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Computed Tomography ◽  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Bone Geometry ◽  
Peripheral Quantitative Computed Tomography ◽  
Volumetric Bone Mineral Density ◽  
Mineral Density

Objective.To investigate the effect of rheumatoid arthritis (RA) on volumetric bone mineral density (vBMD) and bone geometry in postmenopausal women treated with bisphosphonates.Methods.Fifty-three postmenopausal women with RA and 87 control subjects, comparable in terms of age, body mass index, and years since menopause, underwent peripheral quantitative computed tomography (pQCT) of the nondominant tibia.Results.At 4% (trabecular site), trabecular bone mineral content (BMC) and vBMD (p < 0.001) were lower in the RA group, while trabecular area was comparable. At 38% (cortical site), cortical BMC (p < 0.01), area (p < 0.05), and thickness (p < 0.001) were lower in the RA group, whereas vBMD was comparable. Endosteal circumference was higher (p < 0.05), whereas periosteal circumference was comparable, indicating cancellization of cortical bone. In the RA group, muscle area was lower (p < 0.001), while at 14% polar stress strength index was significantly lower (p < 0.01) in patients with RA, indicating impairment of bone mechanical properties.Conclusion.RA is associated with negative effects on both cortical and cancellous bone in postmenopausal women treated with bisphosphonates. Cortical geometric properties are also adversely affected mainly by increased endosteal circumference, whereas trabecular geometric properties are generally preserved.

scholarly journals Effect of Primary Hyperparathyroidism on Volumetric Bone Mineral Density and Bone Geometry Assessed by Peripheral Quantitative Computed Tomography in Postmenopausal Women

2006 ◽  
Vol 91 (5) ◽  
pp. 1748-1753 ◽  
Author(s):  
Ioannis Charopoulos ◽  
Symeon Tournis ◽  
George Trovas ◽  
Panagiota Raptou ◽  
Philippos Kaldrymides ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Peripheral Quantitative Computed Tomography ◽  
Volumetric Bone Mineral Density ◽  
Healthy Controls ◽  
Strength Index ◽  
Mineral Density

Context: Primary hyperparathyroidism (PH) is characterized by inappropriate PTH elevation with or without hypercalcemia. Bone disease involves catabolic action at cortical sites, whereas cancellous sites and geometry might be relatively preserved. Objective: Our objective was to examine the effect of PH on quantitative and qualitative bone characteristics using peripheral quantitative computed tomography at the tibia in postmenopausal women with PH and healthy controls. Design and Setting: We conducted a cross-sectional study at a tertiary referral center. Patients: Fifty-two postmenopausal women with PH and 56 healthy controls, comparable for age and anthropometric measures, participated. Intervention: There was no intervention. Main Outcome Measure: We assessed volumetric bone mineral density (vBMD), bone mineral content (BMC), cortical thickness, cortical and trabecular area, peri- and endosteal circumference, and polar stress strength index assessed by peripheral quantitative computed tomography of the left tibia at 4% (cancellous), 14% (transition zone), and 38% (cortical) from the distal end. Results: At 4%, there was a significant decrease of trabecular BMC and vBMD (P &lt; 0.001), effect particularly evident in hypercalcemic patients, whereas trabecular area was comparable. At 38%, cortical BMC (P &lt; 0.01), vBMD (P &lt; 0.01), area (P &lt; 0.05), and thickness (P &lt; 0.001) were reduced in the PH group, particularly in hypercalcemic patients. Endosteal circumference increased (P &lt; 0.001), whereas periosteal circumference was comparable, indicating cancellization of cortical bone. At 14%, polar stress strength index was significantly decreased (P &lt; 0.01) in hypercalcemic patients, indicating impairment of bone mechanical properties. Conclusions: Normocalcemic PH is characterized by catabolic actions at both cortical and cancellous sites (38 and 4%, respectively), an effect accentuated in hypercalcemic patients. Cortical geometric properties are adversely affected even in normocalcemic patients, whereas trabecular properties are generally preserved.

scholarly journals Comparison of the Proximal Phalanx Parameters in Warmblood and Coldblood Horses with the Use of Peripheral Quantitative Computed Tomography

2012 ◽  
Vol 56 (4) ◽  
pp. 637-642 ◽  
Author(s):  
Małgorzata Dzierzęcka ◽  
Anna Charuta
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Proximal Phalanx ◽  
Quantitative Computed Tomography ◽  
Peripheral Quantitative Computed Tomography ◽  
Volumetric Bone Mineral Density ◽  
Bone Area ◽  
Mineral Density ◽  
Bone Length

Abstract The aim of the study was to compare densitometric and geometric parameters of the proximal phalanges in forelimbs of Warmblood and Coldblood horses, at 15%, 50%, and 85% of the bone proximal length. Peripheral quantitative computed tomography was used to analyse the structure of phalanges. The following parameters were determined: bone mineral content, volumetric bone mineral density, total bone area, trabecular area, cortical area, cortical thickness, periosteal circumference, endocortical circumference, and strength strain index. The most significant differences between pastern bones in thoracic limbs of the horses were visible in the proximal and distal metaphyseal parts, for instance. at 15% and 85% of the bone length, respectively. Statistical analysis showed that at 15% of the bone length, total bone area, trabecular area, periosteal circumference, and endocortical circumference were significantly higher in Warmblood horses. At the mid-shaft, volumetric bone mineral density and endocortical circumference were significantly higher in Coldblood horses. At 85% of the bone length, volumetric bone mineral density, total bone area, trabecular area, periosteal circumference, and endocortical circumference were significantly higher in Coldblood horses.

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