Morphologic and histologic study of the ligamentum flavum in the thoraco-lumbar region

1998 ◽  
Vol 20 (3) ◽  
pp. 171-176 ◽  
Author(s):  
D. Viejo-Fuertes ◽  
D. Liguoro ◽  
J. Rivel ◽  
D. Midy ◽  
J. Guerin
Keyword(s):  
Ligamentum Flavum ◽  
Lumbar Region ◽  
Histologic Study

scholarly journals The Posterior Epidural Ligaments: A Cadaveric and Histological Investigation in the Lumbar Region

ISRN Anatomy ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
M. J. Connor ◽  
S. Nawaz ◽  
V. Prasad ◽  
S. Mahir ◽  
R. Rattan ◽  
...  
Keyword(s):  
Dura Mater ◽  
Spinal Surgery ◽  
Ligamentum Flavum ◽  
Dorsal Surface ◽  
Lumbar Region ◽  
Intraoperative Awareness ◽  
Cross Sectional ◽  
Poorly Differentiated ◽  
Lumbar Spinal ◽  
Incidental Durotomy

Purpose. Incidental durotomy is a relatively common complication for patients undergoing posterior spinal surgery. Delineating anatomical variants in the posterior lumbar spinal canal is crucial in reducing future rates of incidental durotomy. Materials and Methods. The ligamentous attachments between the dura mater and ligamentum flavum in the lumbar region of 17 soft-fixed cadavers were investigated. The lumbar vertebral columns were removed, and cross-sectional dissection was performed at levels L1-S1. Anterior retraction of the dorsal dura mater identified attachments between the dorsal surface of the dura mater and the ligamentum flavum. Histological staining of the ligamentous attachments was carried out with hematoxylin and eosin (H&E) and elastic van Gieson (EVG). Results. Posterior epidural ligaments were present in 9 (52.9%) cadavers. Nine (9) separate ligaments were identified in these cadavers, with 3 (33.3%) at L3/L4, 5 (55.5%) at L4/L5, and 1 (11.1%) at L5/S1. Histology confirmed the presence of poorly differentiated collagen-based connective tissue, distinct from the normal anatomy. Conclusions. This study confirms the presence of multiple dorsomedial posterior epidural ligaments at the main sites for posterior spinal surgery (L3-S1). An intraoperative awareness of the variability of such connections may be an important step in reducing static rates of incidental durotomy.

scholarly journals Haemorrhagic Lumbar Juxtafacet Cyst with Ligamentum Flavum Involvement

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Finn Ghent ◽  
Trent Davidson ◽  
Ralph Jasper Mobbs
Keyword(s):  
Ligamentum Flavum ◽  
Lumbar Region ◽  
Juxtafacet Cyst ◽  
Acute Radiculopathy

Juxtafacet cysts are an uncommon cause of radiculopathy. They occur most frequently in the lumbar region, and their distribution across the spine correlates with mobility. Haemorrhagic complications are rare and may occur in the absence of any provocation, although there is some association with anticoagulation and trauma. We present a case of acute radiculopathy due to an L5/S1 juxtafacet cyst with unprovoked haemorrhage which was found to extend into ligamentum flavum. The patient underwent uncomplicated microscope assisted decompression with excellent results. The demographics, presentation, aetiology, and management of juxtafacet cysts are discussed.

scholarly journals Ligamentum flavum hematoma: a case report and literature review

2012 ◽  
Vol 11 (1) ◽  
pp. 81-83
Author(s):  
Ericson Sfreddo ◽  
Marcelo Teodoro Ezequiel Guerra
Keyword(s):  
Ligamentum Flavum ◽  
Cauda Equina ◽  
Neurogenic Claudication ◽  
Lumbar Region ◽  
Small Vessels ◽  
Degenerative Lumbar Spondylolisthesis ◽  
Narrow Spinal Canal ◽  
Lumbar Spondylolisthesis ◽  
Expansive Lesion

The aim is to present a rare case of ligamentum flavum hematoma in the lumbar region, discuss its physiopathology and treatment and review the literature. A woman aged 68 presented with neurogenic claudication due to degenerative lumbar spondylolisthesis that evolved into a sudden worsening with cauda equina syndrome. The magnetic resonance imagining (MRI) showed signs of degeneration of the lumbar spine, with a narrow spinal canal from L2 to S1, anterolisthesis L4 L5 and an expansive lesion hyperintense on T1-weighted and hypointense on T2-weighted images considered compatible with hematoma in the topography of the yellow ligament in L1-L2. The patient underwent laminectomy and lumbar fixation. Her evolution was good in the postoperative period and at 18 months of follow-up hse walked alone, despite the pain that is controlled with simple medications. Even though rare, it seems that ligamentum flavum hematoma has a relationship with the degeneration and rupture of small vessels associated with micro trauma to the spine. Its physiopathology is not well defined and treatment is similar to other spine compression processes.

COLLAGEN AND ELASTIN CROSSLINKS IN HUMAN INTERVERTEBRAL DISCS AND LIGAMENTUM FLAVUM: AGE, GENDER AND SPINAL LEVEL INFLUENCES

2002 ◽  
Vol 06 (02) ◽  
pp. 73-88
Author(s):  
C. I. Tan ◽  
G. N. Kent ◽  
A. G. Randall ◽  
S. J. Edmondston ◽  
K. P. Singer
Keyword(s):  
Ligamentum Flavum ◽  
Intervertebral Discs ◽  
Lumbar Region ◽  
Spinal Level ◽  
Reverse Phase Hplc ◽  
Collagen Crosslinks ◽  
Tissue Samples ◽  
Spinal Region ◽  
The Mean ◽  
Formalin Fixed

The collagen and elastin content and extent of collagen crosslinks were determined in human formalin-fixed and unfixed intervertebral discs and ligamentum flava. Tissue samples from cadaveric spinal discs (n = 77) and ligamentum flava (n = 364) were obtained from 24 formalin-fixed and 2 fresh spines. The mean age of all cases was 57±26 years. Spinal ligament and disc samples were harvested and analyzed for collagen, and crosslinks of pyridinoline, deoxypyridinoline, and elastin crosslinks isodesmosine and desmosine. Collagen and elastin crosslinks were extracted from hydrolyzed samples by cellulose partition chromatography, and analyzed by reverse-phase HPLC. Elastin crosslinks were only detected in 4 lumbar discs (mean 0.04±0.01 nmol/mg dry wt) but yielded results for all ligamentum flavum samples (mean 20.2±6.4 nmol/mg dry wt). For ligamentum flavum, the collagen and collagen crosslinks increased significantly with age (p < 0.05), whereas elastin content decreased significantly with age but only for the lumbar region (p < 0.05). Collagen and elastin content were significantly higher in females (p < 0.01) and collagen, pyridinoline and isodesmosine were significantly higher in the lumbar region (p < 0.01). Elastin detected in lumbar discs was significantly less than that found in ligamentum flavum. The collagen and elastin content and extent of collagen crosslinks in ligamentum matrix varied significantly depending on the age, gender and spinal region.

scholarly journals Hypertrophy of the ligamentum flavum and expression of transforming growth factor beta

2017 ◽  
Vol 45 (6) ◽  
pp. 2036-2041 ◽  
Author(s):  
Aierken Amudong ◽  
Aikeremujiang Muheremu ◽  
Tuerhongjiang Abudourexiti
Keyword(s):  
Growth Factor ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Ligamentum Flavum ◽  
Inflammatory Cells ◽  
Lumbar Region ◽  
Cellular Apoptosis ◽  
Growth Factor Beta ◽  
Immunohistochemical Studies ◽  
Lumbar Spinal

Objective To explore the relationship between cellular apoptosis and hypertrophy of the ligamentum flavum in the lumbar region. Methods Thirty patients with lumbar spinal stenosis were evaluated. Hypertrophy of the ligamentum flavum was present in 15 patients and absent in 15. Hematoxylin–eosin staining and transforming growth factor beta (TGF-β) immunohistochemical testing were applied to compare these two groups. Results Derangement of fibrous alignment, fibrocartilage changes, and infiltration of inflammatory cells were observed in the patients with hypertrophy of the ligamentum flavum, while fibrous alignment was normal and few inflammatory cells were observed in patients without hypertrophy. Immunohistochemical studies showed positive expression of TGF-β in patients with hypertrophy, while expression was negative in patients without hypertrophy. The integrated optical density was 2.6556708 in the hypertrophy group and 23104671 in the normal controls. Conclusions Expression of TGF-β was closely related to hypertrophy of the ligamentum flavum. Appropriate application of the TGF-β expression level can be used to predict progression of hypertrophy of the ligamentum flavum.

514: A Histologic Study of Urethral Plate with Light and Transmission Electron Microscopy

2006 ◽  
Vol 175 (4S) ◽  
pp. 167-167
Author(s):  
Hyuk Sao Chang ◽  
Choal Hee Park ◽  
Chun I.I. Kim ◽  
Kwang Sae Kim
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Histologic Study ◽  
Urethral Plate ◽  
Transmission Electron

The examination of biophysical parameters of skin (transepidermal water loss, skin hydration and pH value) in different body regions of ponies

2012 ◽  
Vol 15 (3) ◽  
pp. 553-559 ◽  
Author(s):  
M.P. Szczepanik ◽  
P.M. Wilkołek ◽  
M. Pluta ◽  
Ł.R. Adamek ◽  
Z.J.H. Pomorski
Keyword(s):  
Water Loss ◽  
Ph Value ◽  
Neck Region ◽  
Transepidermal Water Loss ◽  
Skin Hydration ◽  
Lumbar Region ◽  
Biophysical Parameters ◽  
Body Regions ◽  
Skin Ph

Abstract The purpose of this study was to evaluate transepidermal water loss, skin hydration and skin pH in normal ponies. Sixteen ponies of both sexes were examined in the study. Measurements were taken from seven different sites: the neck region, the shoulder, thorax, lumbar, inguinal, lip region and the auricle. In each of the regions transepidermal water loss (TEWL), skin hydration and skin pH were measured. For transepidermal water loss, the lowest values were observed in the lumbar region (9.71g/hm2), while the highest values were observed in the lip region (22.35 g/hm2). In the case of skin hydration the lowest values were observed for the thorax region (2.13 CU), and the highest for the lip region (41.81 CU). For skin pH, the lowest results were obtained in the lumbar region (6.93), and the highest in the lip region (7.96).

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