Lactate dehydrogenase and alkaline phosphatase isoenzymes and protein-bound sialic acid in regenerating rat liver

1986 ◽  
Vol 186 (2) ◽  
pp. 103-107 ◽  
Author(s):  
D. Allalouf ◽  
S. Schwarzman ◽  
H. Levinsky ◽  
N. Feller ◽  
J. Hart ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Sialic Acid ◽  
Lactate Dehydrogenase ◽  
Rat Liver ◽  
Regenerating Rat Liver ◽  
Alkaline Phosphatase Isoenzymes

scholarly journals Metabolism of sialic acid in regenerating rat liver

1981 ◽  
Vol 194 (3) ◽  
pp. 1031-1031
Keyword(s):  
Sialic Acid ◽  
Rat Liver ◽  
Regenerating Rat Liver

Sialic acid metabolism in regenerating rat liver

1981 ◽  
Vol 13 (4) ◽  
pp. 281-289 ◽  
Author(s):  
Gollamudi S. Kishore ◽  
Raoul Carubelli
Keyword(s):  
Sialic Acid ◽  
Rat Liver ◽  
Acid Metabolism ◽  
Regenerating Rat Liver

scholarly journals Metabolism of sialic acid in regenerating rat liver

1980 ◽  
Vol 188 (3) ◽  
pp. 905-911 ◽  
Author(s):  
Y Okamoto ◽  
N Akamatsu
Keyword(s):  
Sialic Acid ◽  
Partial Hepatectomy ◽  
Rat Liver ◽  
Similar Pattern ◽  
Early Stage ◽  
Acetylneuraminic Acid ◽  
Control Value ◽  
Liver Slices ◽  
Regenerating Rat Liver ◽  
Free Sialic Acid

In regenerating rat liver slices 24 h after partial hepatectomy, the incorporation of [1-14C]glucosamine into ‘free sialic acid’ (N-acetylneuraminic acid + CMP-N-acetylneuraminic acid) decreased to below 50% of the control values and the incorporation into protein-bound sialic acid decreased to the same extent. The incorporation of [14C]glucosamine into ‘free sialic acid’ decreased during the period from 6 to 47 h after hepatectomy, showing a minimum at 12 h, and recovered to the control value by 96 h. At 12 h, the activities of UDP-N-acetylglucosamine 2-epimerase (UDP-2-acetoamido-2-deoxy-D-glucose 2-epimerase, EC 5.1.3.14) and N-acyl-D-mannosamine kinase (ATP: 2-acylamino-2-deoxy-D-mannose 6-phosphotransferase, EC 2.7.1.60) in the liver were significantly decreased. The amount of protein-bound sialic acid in the liver was not changed after partial hepatectomy, but the amount in plasma was changed, with a similar pattern to that of the incorporation of [14C]glucosamine into slice ‘free sialic acid’. These results indicate that the synthesis of sialic acid in the liver much decreases in the early stage of regeneration and that this may be correlated with the decreased synthesis of plasma sialoglycoproteins.

scholarly journals Electrophoretic Study of Lactate Dehydrogenase and Alkaline Phosphatase Isoenzymes of the Mongolian Gerbil(Meriones unguiculatus).

1996 ◽  
Vol 58 (5) ◽  
pp. 401-406
Author(s):  
Masumi SHIMIZU ◽  
Kazumi IIDA ◽  
Haruhiro YOSHIDA ◽  
Kazuhiro SHICHINOHE
Keyword(s):  
Alkaline Phosphatase ◽  
Lactate Dehydrogenase ◽  
Mongolian Gerbil ◽  
Meriones Unguiculatus ◽  
Electrophoretic Study ◽  
Alkaline Phosphatase Isoenzymes

Isoenzymes of pyruvate kinase, lactate dehydrogenase and alkaline phosphatase in epithelial cell lines of rat liver

1991 ◽  
Vol 43 (1-2) ◽  
pp. 51-56 ◽  
Author(s):  
G. Kässner ◽  
G. Neupert ◽  
R. Scheibe ◽  
K.-W. Wenzel
Keyword(s):  
Alkaline Phosphatase ◽  
Lactate Dehydrogenase ◽  
Epithelial Cell ◽  
Pyruvate Kinase ◽  
Cell Lines ◽  
Rat Liver ◽  
Epithelial Cell Lines

Cytophotometric analysis of alkaline phosphatase and 5′-nucleotidase activity in regenerating rat liver after partial hepatectomy

1988 ◽  
Vol 6 (1) ◽  
pp. 53-60 ◽  
Author(s):  
Cornelis J. F. Van Noorden ◽  
Ilse M. C. Vogels ◽  
Joop M. Houtkooper
Keyword(s):  
Alkaline Phosphatase ◽  
Partial Hepatectomy ◽  
Rat Liver ◽  
Nucleotidase Activity ◽  
Regenerating Rat Liver ◽  
Cytophotometric Analysis

scholarly journals Serum Profile of Lactate Dehydrogenase (LDH) and Alkaline Phosphatase (ALP) in Alcoholic Liver Diseases

2020 ◽  
Author(s):  
Agnieszka Grytczuk ◽  
Ewa Gruszewska ◽  
Anatol Panasiuk ◽  
Bogdan Cylwik ◽  
Lech Chrostek
Keyword(s):  
Alkaline Phosphatase ◽  
Lactate Dehydrogenase ◽  
Liver Diseases ◽  
Alcoholic Hepatitis ◽  
Relative Concentration ◽  
Alcoholic Cirrhosis ◽  
Total Activity ◽  
Relative Level ◽  
Alkaline Phosphatase Isoenzymes ◽  
Alcoholic Liver Diseases

Abstract Background: Alcohol‐related liver diseases affect the capability of the liver for the synthesis of proteins including enzymes. Among enzymes two expose the liver specific isoenzymes. There are lactate dehydrogenase and alkaline phosphatase. The purpose of this study was to explore the profile of lactate dehydrogenase and alkaline phosphatase isoenzymes in alcoholic liver diseases.Methods: The serum profile of lactate dehydrogenase and alkaline phosphatase isoenzymes was studied in alcoholic cirrhosis and alcoholic hepatitis by electrophoresis method on agarose gel.Results: The relative concentration of LDH 1 isoenzyme is decreased in alcoholic hepatitis, but LDH 4 and LDH 5 isoenzymes are increased. In addition, the relative level of LDH 5 isoenzyme is increased in alcoholic cirrhosis. The concentrations of intermediate isoenzymes (LDH 2 and LDH 3) are reduced in alcoholic cirrhosis. There were also an increase of liver ALP isoenzyme and parallel decrease in its bone isoenzyme in alcoholic hepatitis and cirrhosis. The severity of liver cirrhosis, expressed as a Child-Pugh score, didn’t affect total activity of both enzymes but effects the relative concentration of LDH 2, LDH 3 and LDH 4 isoenzymes.Conclusions: The serum profile of lactate dehydrogenase and alkaline phosphatase isoenzymes alters in alcoholic liver diseases and differs between them. The differences can be explained by the tissue prevalence and metabolic preferences of isoenzymes.

Expression of lactate dehydrogenase A-gene in regenerating rat liver

1988 ◽  
Vol 11 (4) ◽  
pp. 278-284 ◽  
Author(s):  
Seung-Kook Yhu ◽  
Hyun-Sung Park ◽  
Hai-Young Kim ◽  
Ae-Kyung Kim ◽  
Seung Ki Lee
Keyword(s):  
Lactate Dehydrogenase ◽  
Rat Liver ◽  
Regenerating Rat Liver
Sign in / Sign up

Export Citation Format

Share Document