Predictive value of nailfold capillaroscopy in the diagnosis of connective tissue diseases

1996 ◽  
Vol 15 (2) ◽  
pp. 148-153 ◽  
Author(s):  
D. Blockmans ◽  
G. Beyens ◽  
R. Verhaeghe
Keyword(s):  
Connective Tissue ◽  
Predictive Value ◽  
Connective Tissue Diseases ◽  
Nailfold Capillaroscopy

scholarly journals Nailfold capillaroscopy and autoimmune connective tissue diseases in patients from a Portuguese nailfold capillaroscopy clinic

2019 ◽  
Vol 40 (2) ◽  
pp. 295-301 ◽  
Author(s):  
Vera Bernardino ◽  
Ana Rodrigues ◽  
Ana Lladó ◽  
António Panarra
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Diseases ◽  
Nailfold Capillaroscopy

scholarly journals Nailfold Capillaroscopy in Rheumatic Diseases

2020 ◽  
Author(s):  
Abhishek Patil ◽  
Isha Sood
Keyword(s):  
Systemic Sclerosis ◽  
Connective Tissue ◽  
Early Diagnosis ◽  
Rheumatic Diseases ◽  
Connective Tissue Diseases ◽  
Nailfold Capillaroscopy ◽  
Indispensable Tool

Nailfold capillaroscopy (NFC) has developed into an indispensable tool for rheumatologists in the evaluation of rheumatic diseases. It offers various advantages in being rapid, noninvasive, and inexpensive. With NFC we are able to visualize the microcirculatory changes in the nail beds. These changes are key to the pathogenesis of connective tissue diseases such as systemic sclerosis. Hence NFC helps in early diagnosis of various connective tissue diseases. There is a lack of standardization in the techniques used and various capillary parameters studied, which could lead to variation in the reporting of the parameters studied. In this chapter we shall try to highlight the most common parameters studied in capillaroscopy and its utility in various connective tissue diseases.

scholarly journals Lung Ultrasound in the Screening of Pulmonary Interstitial Involvement Secondary to Systemic Connective Tissue Disease: A Prospective Pilot Study Involving 180 Patients

2021 ◽  
Vol 10 (18) ◽  
pp. 4114
Author(s):  
Natalia Buda ◽  
Anna Wojteczek ◽  
Anna Masiak ◽  
Maciej Piskunowicz ◽  
Wojciech Batko ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Sensitivity And Specificity ◽  
Predictive Value ◽  
Lung Ultrasound ◽  
Imaging Modality ◽  
Connective Tissue Diseases ◽  
High Sensitivity ◽  
Study Group ◽  
A Prospective Study

Objectives: The aim of the study was the assessment of lung ultrasound (LUS) as a screening of pulmonary interstitial involvement secondary to systemic connective tissue diseases. Methods: A prospective study was conducted on the study group comprising 180 patients diagnosed with different systemic connective tissue diseases. Each patient underwent lung ultrasound (LUS), high-resolution chest computed tomography (HRCT), and echocardiography (ECHO). Each imaging examination was blinded and performed by an independent operator. LUS was conducted with convex and linear transducers. Results: The sensitivity and specificity of LUS as compared to HRCT in detecting pulmonary interstitial involvement in the study group were 99.3% and 96.4%, respectively; positive predictive value (PPV) 0.7, negative predictive value (NPV) 3.6. Abnormalities indicating interstitial lung disease (ILD) with fibrosis were most frequently localized bilaterally in the lower fields of the lungs, assessed in the dorsal view. Conclusions: LUS is an efficient imaging modality that can detect pulmonary interstitial involvement in patients with systemic connective tissue disease with a high sensitivity and specificity. Further prospective studies conducted on a larger population are deemed necessary.

AB0618 Nailfold Capillaroscopy Changes during Pregnancy in Connective Tissue Diseases

2016 ◽  
Vol 75 (Suppl 2) ◽  
pp. 1115.2-1115
Author(s):  
M. Meroni ◽  
V.L. Ramoni ◽  
A.L. Brucato ◽  
M. Limonta ◽  
C. Pizzorni ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Diseases ◽  
Nailfold Capillaroscopy

Nailfold capillaroscopy microscopy - an interdisciplinary appraisal

VASA ◽  
2016 ◽  
Vol 45 (5) ◽  
pp. 353-364 ◽  
Author(s):  
Peter Franz Klein-Weigel ◽  
Cord Sunderkötter ◽  
Oliver Sander
Keyword(s):  
Differential Diagnosis ◽  
Systemic Sclerosis ◽  
Connective Tissue ◽  
Critical Appraisal ◽  
Connective Tissue Diseases ◽  
Diagnostic Value ◽  
Nailfold Capillaroscopy ◽  
Technical Aspects ◽  
Technical Performance ◽  
Disease Specific

Abstract. Nailfold capillaroscopy is a method of great diagnostic value in the differential diagnosis of primary versus secondary Raynaud´s phenomenon, of systemic sclerosis versus other so called connective tissue diseases and of additional diagnostic value in other entities. Rheumatologists, dermatologists, and angiologists in Germany have convened in an interdisciplinary working group in which they synergistically combined their expertise to develop a common nomenclature and standards for the technical performance of nailfold capillary microscopy. The article gives an overview of historical and technical aspects of capillaroscopy, morphologic findings, and disease-specific patterns. It also provides a critical appraisal of its significance in the diagnosis and sequelae of these interdisciplinarily-managed diseases including its performance in children and gives an excursion in the potential perspectives of capillaroscopy in less common indications.

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