Development of chromatographic method for the determination of degree of polymerisation of polyglycerols and polyglycerol fatty acid esters

2000 ◽  
Vol 51 (1-2) ◽  
pp. 44-52 ◽  
Author(s):  
B. De Meulenaer ◽  
B. Vanhoutte ◽  
A. Huyghebaert
Keyword(s):  
Fatty Acid ◽  
Chromatographic Method ◽  
Fatty Acid Esters ◽  
Degree Of Polymerisation ◽  
Acid Esters

2-Monochloropropanediol (2-MCPD), 3-Monochloropropanediol (3-MCPD), and Glycidol in Infant and Adult/Pediatric Nutritional Formula: Single-Laboratory Validation, First Action 2018.12

2019 ◽  
Vol 102 (4) ◽  
pp. 1205-1220 ◽  
Author(s):  
Jan Kuhlmann
Keyword(s):  
Fatty Acid ◽  
Infant Formula ◽  
Edible Oils ◽  
Accurate Determination ◽  
Fatty Acid Esters ◽  
Method Performance ◽  
Relative Standard ◽  
Single Laboratory ◽  
Acid Esters

Abstract Background: Fatty acid esters of glycidol, 2-Monochloropropanediol (MCPD), and 3-MCPD are heat-induced foodborne processing contaminants with possible adverse health effects. These compounds occur frequently in refined edible oils. Consequently, glycidyl esters and 2- and 3-MCPD esters might also be present in foods that contain refined edible oils. Objective: This manuscript describes the single-laboratory validation of an analytical method for the quantitative determination of glycidol, 2-MCPD, and 3-MCPD present as fatty acid esters or as free 2- or 3-MCPD in infant and adult/pediatric nutritional formula. Methods: Technically, the presented method is based on the combination of a Heat-Ultrasound Pressure-supported Solvent Extraction and a GC–MS determination of glycidol, 2-MCPD, and 3-MCPD. From a chemical perspective, the method includes an alkaline catalyzed transesterification, conversion of the unstable glycidol into monobromopropanediol, and the parallel derivatization of all analytes with phenylboronic acid. Results: Validation results showed that method linearity for all analytes in powdered and liquid infant formula ranged from 0.9981 to 0.9999 (n = 18). Repeatability relative standard deviation values for concentration levels between 1.3 μg/kg and 331 μg/kg were in the range of 1 to 12%. Relative recoveries were found to be between 93 and 107%. The analytes were quantifiable down to 5–10 μg/kg in powdered samples and 1–2 μg/kg in liquid samples. Conclusions: The reported results met actual AOAC Standard Method Performance Requirements. Highlights: In terms of consumer protection, the presented method is a novel approach for the sensitive and accurate determination of glycidol, 2-MCPD, and 3-MCPD in infant formula and related foodstuffs.

scholarly journals Quantitative Determination of Estradiol Fatty Acid Esters in Lipoprotein Fractions in Human Blood

2003 ◽  
Vol 88 (6) ◽  
pp. 2552-2555 ◽  
Author(s):  
Veera Vihma ◽  
Aila Tiitinen ◽  
Olavi Ylikorkala ◽  
Matti J. Tikkanen
Keyword(s):  
Fatty Acid ◽  
Quantitative Determination ◽  
Human Blood ◽  
Fatty Acid Esters ◽  
Acid Esters

Bioanalytical procedures for determination of conjugates or fatty acid esters of ethanol as markers of ethanol consumption: A review

2007 ◽  
Vol 368 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Lucia Politi ◽  
Fabio Leone ◽  
Luca Morini ◽  
Aldo Polettini
Keyword(s):  
Fatty Acid ◽  
Ethanol Consumption ◽  
Fatty Acid Esters ◽  
Acid Esters

scholarly journals Direct Determination of MCPD Fatty Acid Esters and Glycidyl Fatty Acid Esters in Vegetable Oils by LC–TOFMS

2010 ◽  
Vol 88 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Troy D. Haines ◽  
Kevin J. Adlaf ◽  
Robert M. Pierceall ◽  
Inmok Lee ◽  
Padmesh Venkitasubramanian ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Vegetable Oils ◽  
Direct Determination ◽  
Fatty Acid Esters ◽  
Glycidyl Fatty Acid Esters ◽  
Acid Esters

Separation and determination of polyethylene glycol fatty acid esters in cosmetics by a reversed-phase HPLC/ELSD

Talanta ◽  
2008 ◽  
Vol 74 (5) ◽  
pp. 1615-1620 ◽  
Author(s):  
Yong Hwa Lee ◽  
Eun Sook Jeong ◽  
Hwang Eui Cho ◽  
Dong-Cheul Moon
Keyword(s):  
Fatty Acid ◽  
Polyethylene Glycol ◽  
Reversed Phase ◽  
Fatty Acid Esters ◽  
Reversed Phase Hplc ◽  
Acid Esters
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