Separation and estimation of anionic surfactants by thin layer chromatography: i. Mixtures of sodium dodecyl benzenesulfonate, sodium dodecyl sulfate and sodium dodecanesulfonate

1982 ◽  
Vol 59 (2) ◽  
pp. 112-116 ◽  
Author(s):  
Chizuo Yonese ◽  
Takeshi Shishido ◽  
Takahide Kaneko ◽  
Kazushige Maruyama
Keyword(s):  
Sodium Dodecyl Sulfate ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Anionic Surfactants ◽  
Sodium Dodecyl ◽  
Sodium Dodecyl Benzenesulfonate ◽  
Dodecyl Sulfate ◽  
Layer Chromatography

Determination of Sodium Dodecyl Sulfate in Hydrophilic Ointments by Thin-Layer Chromatography With Flame Ionization Detection

1986 ◽  
Vol 75 (6) ◽  
pp. 606-607 ◽  
Author(s):  
Keiko Yamaoka ◽  
Kimiko Nakajima ◽  
Hiroyoshi Moriyama ◽  
Yoshihiro Saito ◽  
Takatoshi Sato
Keyword(s):  
Sodium Dodecyl Sulfate ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Sodium Dodecyl ◽  
Flame Ionization Detection ◽  
Ionization Detection ◽  
Flame Ionization ◽  
Dodecyl Sulfate ◽  
Layer Chromatography

scholarly journals Micelle Enhanced Fluorimetric and Thin Layer Chromatography Densitometric Methods for the Determination of (±) Citalopram and its S - Enantiomer Escitalopram

2009 ◽  
Vol 4 ◽  
pp. ACI.S2274 ◽  
Author(s):  
Elham A. Taha ◽  
Nahla N. Salama ◽  
Shudong Wang
Keyword(s):  
Sodium Dodecyl Sulfate ◽  
Thin Layer ◽  
Sodium Dodecyl ◽  
Enantiomeric Purity ◽  
Racemic Mixture ◽  
Drug Products ◽  
Racemic Form ◽  
Layer Chromatography ◽  
Pure Isomer

Two sensitive and validated methods were developed for determination of a racemic mixture citalopram and its enantiomer s-(+)escitalopram. The first method was based on direct measurement of the intrinsic fluorescence of escitalopram using sodium dodecyl sulfate as micelle enhancer. This was further applied to determine escitalopram in spiked human plasma, as well as in the presence of common and co-administerated drugs. The second method was TLC densitometric based on various chiral selectors was investigated. The optimum TLC conditions were found to be sensitive and selective for identification and quantitative determination of enantiomeric purity of escitalopram in drug substance and drug products. The method can be useful to investigate adulteration of pure isomer with the cheap racemic form.

scholarly journals Thin-layer chromatography of L-carnitine in micellar and cyclodextrin mobile phases

2019 ◽  
Vol 58 (5) ◽  
pp. 62-69
Author(s):  
Anna O. Ustyugova ◽  
◽  
Elena G. Sumina ◽  
Varsenia Z. Uglanova ◽  
Olga N. Novozhilova ◽  
...  
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Separation Efficiency ◽  
Sodium Dodecyl ◽  
Theoretical Plate ◽  
Process Efficiency ◽  
Chromatographic Behavior ◽  
Mobile Phases ◽  
Wide Range ◽  
Layer Chromatography

L-carnitine (lat. Levocarnitinum, eng. Levocarnitine) is a natural substance akin to B vitamins. Normalizing metabolic processes in the human body and having a wide range of therapeutic actions, L-carnitine is widely used in cardiology, neurology, gastroenterology, and sports medicine. Currently, modern analytical techniques, such as mass spectrometry, high performance liquid chromatography, radiation methods, etc., are used to analyze L-carnitine. Most of them are rather expensive and time consuming. Thin-layer chromatography (TLC), which is notable for its simplicity, feasibility of analysis, separation efficiency and low cost, has received much less use. In this regard, the purpose of this work was to reveal the analytical capabilities of water-organic, micellar and cyclodextrin mobile phases for the analysis of L-carnitine by means of TLC. Initial L-carnitine solutions with a concentration of 20 mg/ml were prepared by diluting solutions for injections. Their chromatography was carried out by ascending thin-layer chromatography on plates of various polarities (Sorbfil, Plasmachrom, and RP-18) with a fixed sorbent layer. Aqueous solutions of surfactants (cetyltrimethylammonium bromide, cetylpyridinium chloride, sodium dodecyl sulfate, Triton X-100), of cyclodextrins (-cyclodextrin, 2-hydroxypropyl--cyclodextrin), hydroxypropyl--cyclodextrin) were used as mobile phases. The zone of the main substance (L-carnitine) was identified by treating the plate with a mixture of freshly prepared 0.1N solution of potassium permanganate and 2.0 N acetic acid (the zone was colored in a light yellow color). Main features of the chromatographic behavior of L-carnitine were revealed. Based on the calculation of the number of theoretical plates and the height equivalent to one theoretical plate, it was shown that aqueous micellar and cyclodextrin mobile phases allow one to improve the chromatographic process efficiency and the shape of the chromatographic zones of L-carnitine as compared to water-organic eluents; cheaper Sorbfil plates (Russia) can be used for practical purposes. Optimal chromatographic systems and conditions for their use in the thin-layer chromatography of pharmaceuticals and food products have been selected and substantiated.

scholarly journals Structural-rheological properties of systems based on polymeric hydrogels and anionic surfactants

2020 ◽  
Vol 64 (5) ◽  
pp. 551-557
Author(s):  
S. V. Bucha ◽  
Yu. V. Lipai ◽  
P. D. Vorobiev ◽  
D. V. Cherednichenko ◽  
A. D. Vorobiov ◽  
...  
Keyword(s):  
Sodium Dodecyl Sulfate ◽  
Rheological Properties ◽  
Sodium Oleate ◽  
Polyacrylic Acid ◽  
Anionic Surfactants ◽  
Sodium Dodecyl ◽  
Dodecyl Sulfate ◽  
Polymeric Hydrogels ◽  
The Individual ◽  
Increasing Temperature

The effect of sodium dodecyl sulfate and sodium oleate on the structural-rheological properties of a dispersed hydrogel based on polyacrylic acid was studied. It was shown that the viscosity of hydrogel compositions with surfactants is higher than the viscosity of the individual components and increases with increasing temperature from 20 to 40 °C. Compositions with sodium oleate are non-Newton liquids and exhibit thixotropic properties.

Microextraction-colorimetric determination of anionic surfactants in natural and waste waters

2020 ◽  
Vol 86 (12) ◽  
pp. 5-14
Author(s):  
V. G. Amelin ◽  
Zen Alabden C. Shogah ◽  
D. S. Bolshakov
Keyword(s):  
Methylene Blue ◽  
Sodium Dodecyl Sulfate ◽  
Anionic Surfactants ◽  
Sodium Dodecyl ◽  
Colorimetric Method ◽  
Analytical Signal ◽  
Colorimetric Determination ◽  
Waste Waters ◽  
Relative Standard ◽  
Dodecyl Sulfate

An eco-friendly, simple, rapid and cheap method for determining anionic surfactants in natural and waste waters by microextraction-colorimetric method has been developed. The essence of the proposed approach consisted in extraction and concentration of analytes in an acidic medium in the form of associates with organic reagents (methylene blue and acridine yellow) by dispersion liquid-liquid microextraction using a mixture of chloroform-acetonitrile as an extracting and dispersing solvent, followed by aggregation of extractant microparticles by centrifugation and subsequent measurements of color characteristics using a smartphone. The values of the basic components of the RGB colorimetric system were used as an analytical signal to calculate the final color: The selection of optimal conditions for microextraction concentration of anionic surfactants from natural waters (the nature of the extracting and dispergating solvents, the volume of the dispergating solvent) was performed for the sodium dodecyl sulfate — methylene blue system. To study the colorimetric characteristics of the prepared extracts, a smartphone «iPhone X» was used as a color-registering device equipped with a specialized software product «RGBer». To minimize the measurement error by fixing the distance to the object under study and lighting conditions, we propose an installation that increases the accuracy and sensitivity of the determination and makes the method more mobile. The total content of the most common components of detergents was determined: sodium dodecyl sulfate, sulfonol, laureth sulfate and disodium laureth-3-sulfosuccinate. The detection limits ranged within 0.01 – 0.02 and 0.05 mg/liter. The range of detectable contents for all analytes was 0.05 – 1.0 mg/liter. For the determined surfactants, the equations of the relationship between the analytical signal and the concentration were obtained. The calibration graphs are linear with coefficients of the approximation reliability ≤0.98. The correctness of the method was tested on samples of natural water using the spike test procedure. The relative standard deviation of the analysis results does not exceed 0.13. The analysis duration is 20 – 30 min.

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