Endoscopic evaluation of the depth of invasion of the depressed type early gastric cancer and apparently early advanced cancer in cases of a peptic ulcer within the cancer lesion

1993 ◽  
Vol 28 (2) ◽  
pp. 201-208 ◽  
Author(s):  
Hiroshi Isozaki ◽  
Kunio Okajima ◽  
Shinichi Yamada ◽  
Eiji Nakata ◽  
Yoshi Takeda
Keyword(s):  
Gastric Cancer ◽  
Peptic Ulcer ◽  
Early Gastric Cancer ◽  
Advanced Cancer ◽  
Depth Of Invasion ◽  
Depressed Type ◽  
Endoscopic Evaluation ◽  
Cancer Lesion

Laparoscopic Surgery for Early Gastric Cancer: Lesion-Lifting Method and Intragastric Mucosal Resection

2000 ◽  
pp. 97-111
Author(s):  
M. Ohgami ◽  
Y. Otani ◽  
T. Furukawa ◽  
K. Kumai ◽  
T. Kubota ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Laparoscopic Surgery ◽  
Early Gastric Cancer ◽  
Mucosal Resection ◽  
Cancer Lesion

scholarly journals Factors Affecting the Accuracy of Endoscopic Ultrasonography in the Diagnosis of Early Gastric Cancer Invasion Depth: A Meta-analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-11
Author(s):  
Ding Shi ◽  
Xiao-xia Xi
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Likelihood Ratio ◽  
Endoscopic Ultrasonography ◽  
Positive Likelihood Ratio ◽  
Negative Likelihood Ratio ◽  
Diagnostic Value ◽  
Depth Of Invasion ◽  
Invasion Depth ◽  
Sensitivity Specificity

Background. Endoscopic ultrasonography (EUS) is the first imaging modality for investigating the depth of invasion in early gastric cancer (EGC). However, there is presently no consensus on the accuracy of EUS in diagnosing the invasion depth of EGC. Aim. This study is aimed at systematically evaluating the accuracy of EUS in diagnosing the invasion depth of EGC and its affecting factors. Methods. The literatures were identified by searching PubMed, SpringerLink, Cochrane Library, Web of Science, Nature, and Karger knowledge databases. Two researchers extracted the data from the literature and reconstructed these in 2×2 tables. The Meta-DiSc software was used to evaluate the overall sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic advantage ratio, and 95% confidence interval (CI). The SROC was drawn, and the area under the curve (AUC) was calculated to evaluate the diagnostic value. Results. A total of 17 articles were selected, which included 4525 cases of lesions. The sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic dominance ratio, and 95% CI of EUS for diagnosing EGC was 0.87 (95% CI: 0.86-0.88), 0.67 (95% CI: 0.65-0.70), 2.90 (95% CI: 2.25-3.75), 0.17 (95% CI: 0.13-0.23), and 18.25 (95% CI: 12.61-26.39), respectively. The overall overstaging rate of mucosa/submucosa 1 (M/SM1) and SM by EUS was 13.31% and 32.8%, respectively, while the overall understaging rate of SM was 29.7%. The total misdiagnosis rates for EUS were as follows: 30.4% for lesions≥2 cm and 20.9% for lesions<2 cm, 27.7% for ulcerative lesions and 21.4% for nonulcerative lesions, and 22% for differentiated lesions and 26.9% for undifferentiated lesions. Conclusion. EUS has a moderate diagnostic value for the depth of invasion of EGC. The shape, size, and differentiation of lesions might be the main factors that affect the accuracy of EUS in diagnosing EGC.

Histology as a Prognostic Factor in Early Gastric Cancer

1992 ◽  
Vol 78 (3) ◽  
pp. 181-184
Author(s):  
Massimo Ferrari ◽  
Enrico Ghislandi ◽  
Giuseppe Landonio ◽  
Margherita Majno ◽  
Tiziano Porretta ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Lymph Node ◽  
Prognostic Factor ◽  
Early Gastric Cancer ◽  
Lymph Node Involvement ◽  
Depth Of Invasion ◽  
Undifferentiated Histology ◽  
Node Involvement

Of 431 patients with gastric cancer observed in our Istitution, 23 (5.3 %) had early gastric cancer (EGC). Macroscopic presentation, histology, depth of invasion, and lymph node involvement were evaluated in all the cases. All patients underwent surgery and an intensive follow-up was performed. Five of the 23 patients progressed, and the risk factors were examined. Histology seemed to be the main prognostic factor in our study, since intestinal type of EGC was associated to a significantly better prognosis. Total gastrectomy is indicated in the proximal localization of EGC, and should perhaps be performed also in cases presenting undifferentiated histology.

Endoscopic ultrasonography and endoscopy for staging depth of invasion in early gastric cancer: a pilot study

1997 ◽  
Vol 46 (3) ◽  
pp. 212-216 ◽  
Author(s):  
Hideo Yanai ◽  
Yasuke Matsumoto ◽  
Toshiya Harada ◽  
Makoto Nishiaki ◽  
Hiroshi Tokiyama ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Pilot Study ◽  
Early Gastric Cancer ◽  
Endoscopic Ultrasonography ◽  
Depth Of Invasion

scholarly journals Comparison of Diagnostic Potency between Fiberscopic Images and Electronic Endoscopic Ones for Depressed Type of Early Gastric Cancer

1993 ◽  
Vol 43 (0) ◽  
pp. 96-99
Author(s):  
Hisao Nakai ◽  
Masahito Ohida ◽  
Sayuri Yamagata ◽  
Tomoya Kan ◽  
Satoshi Tanabe ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Depressed Type

Endoscopic features of submucosal invasion in undifferentiated type early gastric cancer sized less than 2 cm without ulceration.

2019 ◽  
Vol 37 (4_suppl) ◽  
pp. 76-76
Author(s):  
Su Jin Kim ◽  
Cheol Woong Choi ◽  
Dae Hwan Kang
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Early Gastric Cancer ◽  
Treatment Modality ◽  
Multivariable Analysis ◽  
Submucosal Invasion ◽  
Depth Of Invasion ◽  
Invasion Depth ◽  
Submucosal Cancer ◽  
Undifferentiated Type

76 Background: The prediction of invasion depth is important to decide the treatment modality for the undifferentiated type early gastric cancer (EGC) when size is less than 2 cm and had no ulceration. We aimed to identify the endoscopic features associated with submucosal invasion in the undifferentiated type EGC that meet the criteria of size and status of ulcer in the endoscopic submucosal dissection (ESD). Methods: A total of 120 patients with undifferentiated type EGC who received ESD or operation from August 2008 to December 2017 were enrolled in this study. All lesions met the ESD criteria except the invasion depth. We retrospectively reviewed endoscopic features of tumor before the resection and depth of invasion after resection. Results: In 120 undifferentiated EGCs, the mucosal and submucosal cancer were 97 and 23 lesions, respectively, In univariable analysis, discolor change, upper third location, the presence of deep/wide erosion were associated with submucosal invasion. Multivariable analysis revealed that upper/middle third location (odds ratio [OR] 8.0, 95% confidence interval [CI] 1.2-55.0; OR 7.9, 95% CI 1.8-35.1), erosion or polypoid (OR 41.8, 95% CI 4.1-427.9), and elevated type (OR 20.9, 95% CI 2.5-173.8) were significant risk factors. In 112 patients received gastrectomy with lymph nodes dissection, lymph node metastases were found in four cases (three mucosal cancer and one submucosal cancer). However, there was no lymph node metastasis in the lesions meeting the expanded ESD indication. Conclusions: The careful decision of treatment modality is needed for undifferentiated type EGC with erosion or elevated gross type located on the upper/middle third, although the tumor size and ulcer status meet the ESD indication.

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