Effect of Zishen Yutai pill on embryo implantation rate in patients undergoing fertilization embryo transfer in vitro

2003 ◽  
Vol 9 (1) ◽  
pp. 15-15 ◽  
Author(s):  
Zhu Wen-jie ◽  
Li Xue-mei ◽  
Chen Xiu-min ◽  
Zhang Li
Keyword(s):  
Embryo Transfer ◽  
Embryo Implantation ◽  
Implantation Rate ◽  
Embryo Implantation Rate

scholarly journals Tumor necrosis factor-308 polymorphism increases the embryo implantation rate in women undergoing in vitro fertilization

2013 ◽  
Vol 28 (10) ◽  
pp. 2774-2783 ◽  
Author(s):  
F. Vialard ◽  
M. El Sirkasi ◽  
V. Tronchon ◽  
R. Boudjenah ◽  
D. Molina-gomes ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Embryo Implantation ◽  
Implantation Rate ◽  
Vitro Fertilization ◽  
Embryo Implantation Rate ◽  
Necrosis Factor

scholarly journals Granulocyte Colony-Stimulating Factor Combined With Transcutaneous Electrical Acupoint Stimulation in Treatment of Unresponsive Thin Endometrium in Frozen Embryo Transfer Cycles

2021 ◽  
Vol 3 ◽  
Author(s):  
Linjiang Song ◽  
Qinxiu Zhang ◽  
Shaomi Zhu ◽  
Xudong Shan
Keyword(s):  
Embryo Transfer ◽  
Endometrial Thickness ◽  
Embryo Implantation ◽  
Implantation Rate ◽  
Granulocyte Colony Stimulating Factor ◽  
Thin Endometrium ◽  
Treatment Groups ◽  
Stimulating Factor ◽  
Embryo Implantation Rate ◽  
Acupoint Stimulation

Objective: This trial was designed to assess the treatment effects of granulocyte colony-stimulating factor (G-CSF) and transcutaneous electrical acupoint stimulation (TEAS) on thin endometrium in frozen-thawed embryo transfer (FET) cycles.Methods: Ninety-nine patients with previous cancellations of embryo transfer were included, 56 of whom were prospectively treated with intrauterine perfusion of G-CSF in subsequent FET cycles. The selected patients were randomized into the G-CSF perfusion only group and the G-CSF perfusion combined with TEAS group. The other 43 patients were retrospectively included as controls.Results: Compared to previous cycles, endometrial thickness was statistically significantly increased in the two treatment groups (5.97 ± 0.60, 7.52 ± 0.56, 6.14 ± 0.52, and 7.66 ± 0.44; P = 0.00 and 0.00, respectively). The increases in endometrial thickness suggested that no statistically significant difference was found between the two treatment groups. The G-CSF with TEAS group suggested a higher embryo implantation rate than the G-CSF perfusion only and control groups (33.33 and 29.1% and 33.33 and 17.39%; P = 0.412 and 0.091, respectively). The G-CSF combined with TEAS group demonstrated nominally higher clinical and ongoing pregnancy rates than the G-CSF perfusion-only group and controls, though, the difference was not statistically significant.Conclusion: G-CSF has a potential role in improving endometrium thickness in patients with thin unresponsive endometrium in FET treatment cycles. In addition, when combined with TEAS, G-CSF perfusion treatment also improves the embryo implantation rate; however, randomized controlled trials are highly demanded to provide high-grade evidence regarding clinical pregnancy rate after G-CSF perfusion treatment.

Surrogacy in Australia: implantation rates have implications for embryo quality and uterine receptivity

2001 ◽  
Vol 13 (1) ◽  
pp. 99 ◽  
Author(s):  
M. A. Stafford-Bell ◽  
C. M. Copeland
Keyword(s):  
Embryo Transfer ◽  
Embryo Implantation ◽  
Implantation Rate ◽  
Live Birth Rate ◽  
Uterine Receptivity ◽  
Comparable Group ◽  
Embryo Implantation Rate ◽  
Gestational Carrier ◽  
Frozen Embryo Transfers ◽  
Frozen Thawed Embryo Transfer

Since the passage, in November 1995, of the ACT Substitute Parents Agreement Act, The Canberra Fertility Centre has added a true gestational carrier pregnancy programme to its established infertility and IVF services. Embryos generated are transferred as frozen–thawed embryos to the carrier in an average of 2.2 embryos per transfer. Between 1 January 1996 and 31 December 1999 the results of 49 frozen embryo transfers to 25 gestational carriers were compared with 849 frozen embryo transfers on a routine IVF programme. In the carrier group, the embryo implantation rate of 13.8% per embryo transferred is double that of an exactly comparable group of patients undergoing routine frozen–thawed embryo transfer on the same IVF programme and considerably higher than those reported in large series of frozen–thawed embryo transfers. Exclusion from the carrier pregnancy programme of patients with incipient ovarian failure results in an implantation rate of 16.7%, a clinical pregnancy rate of 29.0% and a live birth rate of 19.4% per embryo transfer procedure.

Age-dependent decrease in embryo implantation rate after in vitro fertilization

1996 ◽  
Vol 66 (5) ◽  
pp. 769-775 ◽  
Author(s):  
Roelof J. van Kooij ◽  
Caspar W.N. Looman ◽  
Johannes D.F. Habbema ◽  
Marinus Dorland ◽  
Egbert R. te Velde
Keyword(s):  
In Vitro Fertilization ◽  
Embryo Implantation ◽  
Implantation Rate ◽  
Vitro Fertilization ◽  
Age Dependent ◽  
Embryo Implantation Rate

scholarly journals Should rescue ICSI be re-evaluated considering the deferred transfer of cryopreserved embryos in in-vitro fertilization cycles? A systematic review and meta-analysis

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Alessio Paffoni ◽  
Marco Reschini ◽  
Valerio Pisaturo ◽  
Cristina Guarneri ◽  
Simone Palini ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Pregnancy Rate ◽  
Embryo Transfer ◽  
Implantation Rate ◽  
Clinical Pregnancy ◽  
Frozen Embryo Transfer ◽  
Fertilization Failure ◽  
Vitro Fertilization ◽  
Rescue Icsi

Abstract Background Total fertilization failure represents a particularly frustrating condition for couples undergoing in vitro fertilization. With the aim of reducing the occurrence of total fertilization failure, intracytoplasmic sperm injection (ICSI) has become the first choice over conventional in vitro fertilization (IVF) procedures although evidence of improved results is still debated and its use in couples without male factor infertility is not recommended. Among the strategies potentially useful to promote the use of conventional IVF, we herein call attention to the late rescue ICSI, which consists in performing ICSI after 18–24 h from conventional insemination on oocytes that show no signs of fertilization. This treatment has however been reported to be associated with a low success rate until recent observations that embryos derived from late rescue ICSI may be transferred after cryopreservation in a frozen-thawed cycle with improved results. The aim of the present study was to assess whether frozen embryos deriving from rescue ICSI performed about 24 h after conventional IVF may represent a valuable option for couples experiencing fertilization failure. Methods A systematic review on the efficacy of late rescue ICSI was performed consulting PUBMED and EMBASE. Results Including twenty-two original studies, we showed that clinical pregnancy rate per embryo transfer and implantation rate obtainable with fresh embryo transfers after rescue ICSI are not satisfactory being equal to 10 and 5%, respectively. The transfer of cryopreserved rescue ICSI embryos seems to offer a substantial improvement of success rates, with pregnancy rate per embryo transfer and implantation rate equal to 36 and 18%, respectively. Coupling rescue ICSI with frozen embryo transfer may ameliorate the clinical pregnancy rate for embryo transfer with an Odds Ratio = 4.7 (95% CI:2.6–8.6). Conclusion Results of the present review support the idea that r-ICSI coupled with frozen embryo transfer may overcome most of the technical and biological issues associated with fresh transfer after late r-ICSI, thus possibly representing an efficient procedure for couples experiencing fertilization failure following conventional IVF cycles. Trial registration Prospero registration ID: CRD42021239026.

scholarly journals Efficiency Comparison Between Dry And Humid Cultures For Clinical Outcome of The In Vitro Fertilization-Embryo Transfer

2021 ◽  
Author(s):  
Weihai Xu ◽  
Lin Zhang ◽  
Ling Zhang ◽  
Shishi Li ◽  
Jing Shu
Keyword(s):  
In Vitro Fertilization ◽  
Embryo Transfer ◽  
Implantation Rate ◽  
Fertilization Rate ◽  
Cleavage Rate ◽  
High Quality ◽  
Vitro Fertilization ◽  
Efficiency Comparison ◽  
Ivf Et

Abstract Background: In this study, we compared the in vitro embryo development, embryo transfer outcome and the offspring outcome in the in vitro fertilization-embryo transfer (IVF-ET) between dry culture (DC) and humid culture (HC). Methods: Our study was divided into two parts. Firstly, we determined the fertilization rate, cleavage rate and high-quality embryo rate from 21 cycles in the DC group (N=262 oocytes) and HC group (N=263 oocytes). Secondly, we determined the embryo transfer outcome and the offspring outcome in DC group (N=184 cycles) and HC group (N=136 cycles). Results: Compared with the HC group, significant increase was observed in the high-quality embryo rate (66.1.2% vs. 55.3%, p=0.037) and implantation rate (49.8% vs. 40.6%, p=0.027) in the DC group. No statistical differences were observed in the pregnant outcome and birth defect of the offspring (p>0.05). Compared with HC, DC was associated with a higher high-quality embryo rate and a higher implantation rate after embryo transfer. Conclusions: No statistical differences were noticed in the offspring conditions between the two culture modes. Taken together, DC may serve as a promising method for IVF-ET.

370 BILATERAL DIFFERENTIAL TESTICULAR BIOPSIES IMPROVE TESE AND ICSI OUTCOMES IN NON-OBSTRUCTIVE AND OBSTRUCTIVE AZOOSPERMIC INFERTILE PATIENTS

2007 ◽  
Vol 19 (1) ◽  
pp. 300
Author(s):  
S. M. Al-Ansari ◽  
M. T. Ridha-Albarzanchi ◽  
Z. A. Kanan ◽  
A. A. Al-Badri ◽  
S. K. Al-Atraqchi
Keyword(s):  
Embryo Transfer ◽  
Embryo Implantation ◽  
Implantation Rate ◽  
Seminiferous Tubules ◽  
Testicular Sperm Extraction ◽  
Sperm Retrieval ◽  
Cleavage Rate ◽  
Male Patients ◽  
Testicular Size ◽  
Icsi Outcomes

The goal of the present study was to evaluate the clinical significance of bilateral differential testicular biopsies (BDTB) to improve testicular sperm extraction (TESE) and ICSI outcomes in non-obstructive azoospermic (NOA) men. The male patients were divided into an obstructive azoospermic group (OAG, n = 40) and an NOA group (n = 50). The women in both groups had normal ovulatory cycles and reproductive hormone concentrations. BDTB were taken from upper, middle, and lower zones of the testes. At least 50 transverse histologic sections of seminiferous tubules were examined in each biopsy. The FSH, LH, and prolactin concentrations were significantly higher in the NOA group compared to the OAG (18.3 vs. 6.2 mIU mL-1, 8.5 vs. 4.1 mIU mL-1, and 9.6 vs. 6.4 ng mL-1, respectively; P < 0.01), whereas the testosterone level and testicular size were significantly lower in the NOA group vs. the OAG (3.7 vs. 5.3 ng mL-1 and 3.3 vs. 4.4 cm, respectively; P < 0.01). A new method (BDTB) for scoring testicular biopsies was used. This method is different from Johnson's method as SCO or TF or complete MA. Following positive BDTB results, TESE and ICSI were performed. The oocyte recovery rate/patient was 3.8% (154/40) and 3.6% (178/50) in the OAG and the NOA group, respectively (P > 0.05). The TESE-ICSI rates were 75.9% (117/154) in the OAG and 59.5% (106/178) in the NOA group (P < 0.005). The embryo cleavage rate was significantly higher in the OAG compared to the NOA group (98/117 = 83.8% vs. 66/106 = 62.3%, respectively; P < 0.005). The number of embryos transferred/patient in the OAG was significantly higher compared to that in the NOA group (2.5 vs. 1.3, respectively; P < 0.01). The embryo implantation rate per embryo transfer in the OAG was 52% (51/98) vs. 45.5% (30/66); P > 0.05. The clinical pregnancy rate per embryo transfer was 52.5% in the OAG and 40% in the NOA group (P > 0.05). It was concluded from the results of this study that both the BDTB and TESE were useful diagnostic and prognostic predictors of successful sperm retrieval for ICSI treatment in the non-obstructive and obstructive azoospermic male patients. The clinical embryo implantation rates were not significantly different between both groups (NOA group and OAG) which may indicate that the embryos of both groups have similar implantation potentials. Bilateral differential testicular biopsies were found to be positively correlated with the TESE and ICSI outcomes.

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