Serum clara cell protein (CC16): A new valid marker of the distal airway damages caused by air pollutants in rats

1996 ◽  
Vol 16 (4) ◽  
pp. 223-228 ◽  
Author(s):  
Hong Zhiyong
Keyword(s):  
Air Pollutants ◽  
Clara Cell ◽  
Cell Protein ◽  
Clara Cell Protein ◽  
Distal Airway

scholarly journals Clara cell protein 16 release from the nasal mucosa in allergic rhinitis, chronic rhinosinusitis, and exposure to air pollutants

2018 ◽  
Vol 69 (3) ◽  
pp. 215-219 ◽  
Author(s):  
Aleksandar Perić ◽  
Cveta Špadijer Mirković ◽  
Danilo Vojvodić
Keyword(s):  
Allergic Rhinitis ◽  
Chronic Rhinosinusitis ◽  
Nasal Mucosa ◽  
Air Pollutants ◽  
Clara Cell ◽  
Cell Protein ◽  
Lower Airway ◽  
Clara Cells ◽  
Corticosteroid Administration ◽  
Clara Cell Protein

AbstractClara cell protein 16 (CC16) is a small protein mainly produced by non-ciliated Clara cells in the respiratory epithelium. It has an anti-inflammatory role in chronic upper and lower airway eosinophilic inflammations. Decreased levels of CC16 are found in the nasal secretions and plasma of patients with chronic eosinophilic inflammatory disorders, such as asthma, allergic rhinitis, and chronic rhinosinusitis with or without nasal polyps, as well as in people exposed to high levels of air pollutants. Intranasal corticosteroid administration suppresses chronic inflammation of the nasal mucosa driven by eosinophils and stimulates local CC16 production. CC16 can be a reliable biomarker of the beneficial effects of perennial allergic rhinitis and chronic rhinosinusitis therapy and of the functional recovery of the nasal mucosa after treatment with topical glucocorticoids.

Infant frequent wheezing correlated to Clara cell protein 10 (CC10) polymorphism and concentration, but not allergy sensitization, in a perinatal cohort study

2007 ◽  
Vol 120 (4) ◽  
pp. 842-848 ◽  
Author(s):  
Kuender D. Yang ◽  
Chia-Yu Ou ◽  
Jen-Chieh Chang ◽  
Rong-Fu Chen ◽  
Chieh-An Liu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Clara Cell ◽  
Cell Protein ◽  
Clara Cell Protein

Clara Cell Protein–positive Epithelial Cells Are Reduced in Small Airways of Asthmatics

1999 ◽  
Vol 160 (3) ◽  
pp. 930-933 ◽  
Author(s):  
NORIHARU SHIJUBO ◽  
YOSHIHISA ITOH ◽  
TETSUJI YAMAGUCHI ◽  
AKIHIRO IMADA ◽  
MICHIO HIRASAWA ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Clara Cell ◽  
Cell Protein ◽  
Small Airways ◽  
Clara Cell Protein

The molecular mass and concentrations of protein 1 or Clara cell protein in biological fluids: A reappraisal

1993 ◽  
Vol 223 (1-2) ◽  
pp. 189-191 ◽  
Author(s):  
A. Bernard ◽  
X. Dumont ◽  
H. Roels ◽  
R. Lauwerys ◽  
I. Dierynck ◽  
...  
Keyword(s):  
Molecular Mass ◽  
Biological Fluids ◽  
Clara Cell ◽  
Cell Protein ◽  
Clara Cell Protein
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