New prognostic factors associated with long-term survival in node-negative breast cancer patients

Breast Cancer ◽  
1999 ◽  
Vol 6 (4) ◽  
pp. 370-377 ◽  
Author(s):  
Takao Kato ◽  
Tsunehito Kimura ◽  
Nobue Takami ◽  
Ryuhei Miyakawa ◽  
Schinichi Tanaka ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Term Survival ◽  
Node Negative ◽  
Long Term Survival ◽  
Factors Associated ◽  
Node Negative Breast Cancer

Clinicopathologic features associated with long-term survival in node-negative breast cancer patients

Surgery Today ◽  
1996 ◽  
Vol 26 (2) ◽  
pp. 105-114 ◽  
Author(s):  
Takao Kato ◽  
Tsunehito Kimura ◽  
Ryuhei Miyakawa ◽  
Shinichi Tanaka ◽  
Takako Kamio ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Clinicopathologic Features ◽  
Breast Cancer Patients ◽  
Term Survival ◽  
Node Negative ◽  
Long Term Survival ◽  
Node Negative Breast Cancer

Long-term survival of women with breast cancer with ≥10 lymph nodes at diagnosis.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e11575-e11575
Author(s):  
Ludimila Cavalcante ◽  
Simon B. Zeichner ◽  
Gabriel P Suciu ◽  
Ana L. Ruiz ◽  
Alicia Hirzel ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Lymph Nodes ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Term Survival ◽  
Long Term Survival ◽  
Metastatic Lymph Nodes ◽  
Metastatic Lymph

e11575 Background: Axillary lymph node status is one of the most important prognostic factors in patients with breast cancer, and those with more than ten metastatic lymph nodes at diagnosis have a decreased overall survival. The purpose of this study is to better characterize the clinical course of this high-risk, poorly described patient population and determine the factors associated with long-term survival. Methods: A retrospective cohort analysis of all breast cancer patients with greater than ten metastatic lymph nodes diagnosed at Mt. Sinai Medical Center from January 1990 to December 2007 (n= 175). Descriptive frequencies, overall median survival (OMS), 5- and 10-year survival were calculated for standard prognostic factors and treatment variables. Univariate statistical analysis was performed, followed by a multivariate prognostic analysis for time-to-event data, using the Cox and extended Cox regression model. Results: The majority of patients were non-Hispanic white females between the ages of 56-70, diagnosed between 1990-1999, with tumors between 2-5 cm and 10-15 metastatic lymph nodes. Most were ER/PR positive, HER2 negative, and treated with surgery, chemotherapy, radiation and hormonal therapy. The OMS was 94 months (CI = 69-114) with 5- and 10-year survival rates of 64.3 and 41.6%, respectively. Ages between 21-45 years (OMS of 187 months, p = 0.03), tumors less than 2 cm (146 months (95% CI = 85-198), p = 0.02), ER positivity (131 months (95% CI = 94-157) vs. 39 months (95% CI = 27-59), p = 0.0003) and treatment received between 2000-2003 (98 months (95% CI = 55-133), p = 0.02) were all associated with significantly improved survival. Conclusions: Over the past decade there were significant gains in the long-term survival of breast cancer patients with greater than ten positive nodes at diagnosis, possibly due to improvements in multimodality therapy, such as the introduction of taxanes, although stage migration may be another contributing factor. Our study further showed an encouraging survival for ER positive patients and a dismal one for ER negative patients, highlighting the need for new targeted therapies directed towards ER negative tumors.

scholarly journals A Novel Promoter CpG-Based Signature for Long-Term Survival Prediction of Breast Cancer Patients

2020 ◽  
Vol 10 ◽  
Author(s):  
Yang Guo ◽  
Xiaoyun Mao ◽  
Zhen Qiao ◽  
Bo Chen ◽  
Feng Jin
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Survival Prediction ◽  
Breast Cancer Patients ◽  
Term Survival ◽  
Long Term Survival

scholarly journals Post-surgical depressive symptoms and long-term survival in non-metastatic breast cancer patients at 11-year follow-up

2017 ◽  
Vol 44 ◽  
pp. 16-21 ◽  
Author(s):  
Michael H. Antoni ◽  
Jamie M. Jacobs ◽  
Laura C. Bouchard ◽  
Suzanne C. Lechner ◽  
Devika R. Jutagir ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Depressive Symptoms ◽  
Cancer Patients ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Term Survival ◽  
Long Term Survival

scholarly journals Carcinomatous Pericarditis in 3 Breast Cancer Patients with Long-Term Survival

2012 ◽  
Vol 5 (1) ◽  
pp. 195-201 ◽  
Author(s):  
Takanori Konishi ◽  
Rikiya Nakamura ◽  
Naohito Yamamoto ◽  
Yasuhide Onai ◽  
Toshi Okada ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Term Survival ◽  
Long Term Survival

scholarly journals Recent Improvement in the Long-term Survival of Breast Cancer Patients by Age and Stage in Japan

2018 ◽  
Vol 28 (10) ◽  
pp. 420-427 ◽  
Author(s):  
Akiyo Yoshimura ◽  
Hidemi Ito ◽  
Yoshikazu Nishino ◽  
Masakazu Hattori ◽  
Tomohiro Matsuda ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Recent Improvement ◽  
Term Survival ◽  
Long Term Survival

scholarly journals Nipple sparing mastectomy in breast cancer patients and long-term survival outcomes: An analysis of the SEER database

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0183448 ◽  
Author(s):  
Mingzhu Li ◽  
Kai Chen ◽  
Fengtao Liu ◽  
Fengxi Su ◽  
Shunrong Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Survival Outcomes ◽  
Seer Database ◽  
Breast Cancer Patients ◽  
Term Survival ◽  
Long Term Survival ◽  
Nipple Sparing Mastectomy ◽  
Nipple Sparing
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