Blood cultures and antibiotic use in a neonatal intensive care unit

1992 ◽  
Vol 161 (1) ◽  
pp. 3-4 ◽  
Author(s):  
Marie McDonald ◽  
Anne Moloney ◽  
T. A. Clarke ◽  
T. G. Matthews
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Antibiotic Use ◽  
Blood Cultures

Staphylococcus epidermidis Bacteremia in Neonates: Further Observations and the Occurrence of Focal Infection

PEDIATRICS ◽  
1984 ◽  
Vol 74 (5) ◽  
pp. 832-837 ◽  
Author(s):  
Gary J. Noel ◽  
Paul J. Edelson
Keyword(s):  
Intensive Care Unit ◽  
New York ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Staphylococcus Epidermidis ◽  
Neonatal Intensive Care ◽  
Blood Cultures ◽  
Focal Infection ◽  
Clinically Significant ◽  
Vascular Catheters

The frequency and clinical significance of Staphylococcus epidermidis isolates from blood cultures of neonates collected during a 17-month period in The New York Hospital neonatal intensive care unit (NICU) were reviewed. Twenty-three episodes of clinically significant S epidermidis bacteremia were detected using the criteria of isolation from 3/3 blood culture bottles from a single culture, or isolation from two or more blood cultures taken at different times, or simultaneous isolation from blood and fluid, pus or vascular catheter. Of these 23 episodes of S epidermidis bacteremia, ten were associated with colonized vascular catheters, and four episodes occurred in infants with necrotizing enterocolitis. Focal S epidermidis infection occurred in ten episodes, and persistent bacteremia occurred frequently in this setting. S epidermidis was the most frequent cause of bacteremia in the Neonatal Intensive Care Unit during the period reviewed. Of the isolates determined to be clinically significant, 74% were resistant to methicillin and cephalothin and 91% were resistant to gentamicin. All isolates were sensitive to vancomycin. In addition to removing vascular catheters suspected of being colonized and searching for potential sites of focal infection, an antibiotic regimen that includes vancomycin should be initiated once significant S epidermidis bacteremia has been recognized in the neonate.

scholarly journals Antibiotic Use and Misuse in the Neonatal Intensive Care Unit

2012 ◽  
Vol 39 (1) ◽  
pp. 61-68 ◽  
Author(s):  
Nidhi Tripathi ◽  
C. Michael Cotten ◽  
P. Brian Smith
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Antibiotic Use

scholarly journals Pattern of antibiotic use in neonatal intensive care unit in tertiary care hospital in Southern India

2016 ◽  
pp. 1563-1568
Author(s):  
Anjali Shinde ◽  
Jaydeep Bairagi ◽  
Chitra Khanwelkar ◽  
Ravindra Shinde ◽  
Rajsinh Mohite
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Antibiotic Use ◽  
Southern India ◽  
Care Hospital

scholarly journals Molecular Epidemiology of an Outbreak of Enterobacter cloacae in the Neonatal Intensive Care Unit of a Provincial Hospital in Gauteng, South Africa

1998 ◽  
Vol 36 (10) ◽  
pp. 3085-3087 ◽  
Author(s):  
W. H. van Nierop ◽  
A. G. Duse ◽  
R. G. Stewart ◽  
Y. R. Bilgeri ◽  
H. J. Koornhof
Keyword(s):  
South Africa ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Enterobacter Cloacae ◽  
Blood Cultures ◽  
Pulsed Field Gel Electrophoresis ◽  
Provincial Hospital ◽  
Genotypic Cluster

An outbreak of Enterobacter cloacae in the neonatal intensive care unit of a provincial hospital in Gauteng, South Africa, resulting in nine deaths was investigated. Macrorestriction analysis using pulsed-field gel electrophoresis revealed that three isolates ofE. cloacae from blood cultures of patients, six from environmental sources, and one from the hands of a staff member belonged to the same genotypic cluster.

scholarly journals 198Evaluation of Antibiotic Use in the Neonatal Intensive Care Unit (NICU): from an Antimicrobial Stewardship (AMS) perspective

2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S89-S89
Author(s):  
Joseph Ting ◽  
Karen Ng ◽  
Simon Dobson ◽  
Peter Tilley ◽  
Horacio Osiovich ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Antimicrobial Stewardship ◽  
Neonatal Intensive Care ◽  
Antibiotic Use

Prospective Surveillance of Antibiotic Use in the Neonatal Intensive Care Unit

2015 ◽  
Vol 34 (3) ◽  
pp. 267-272 ◽  
Author(s):  
Joseph B. Cantey ◽  
Phillip S. Wozniak ◽  
Pablo J. Sánchez
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Antibiotic Use ◽  
Prospective Surveillance

scholarly journals Health vigilance concerning bacteremia in neonatology - neonatal intensive care unit at the Mohammed VI University Hospital of Oujda (Morocco): epidemiological profile and antibiotic resistance

2021 ◽  
Vol 319 ◽  
pp. 01011
Author(s):  
Loubna Yacoubi ◽  
Soumia Farih ◽  
Abderazzak Seddari ◽  
Noussaiba Benhamza ◽  
Adnane Aarab ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Antibiotic Resistance ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Blood Cultures ◽  
University Hospital ◽  
Coagulase Negative Staphylococci ◽  
Hygiene Measures ◽  
Epidemiological Profile

The objective of our study was to describe the epidemiological profile of blood culture isolates in the neonatology - neonatal intensive care unit of the Mohammed VI University Hospital of Oujda (Morocco) and to specify the resistance profile of the main germs isolated to antibiotics .This is a retrospective and descriptive study of 21 months from December 14, 2016 to September 14, 2018 and covering all positive blood cultures processed in the microbiology laboratory in accordance with REMIC (reference in medical microbiology) and EUCAST (European Committee on Antimicrobial Susceptibility Testing).contaminated blood cultures were excluded. As results, we collected 275 positive blood cultures. They occurred in the context of intravascular device (IVD) use in 59% (n=162) of cases. The most isolated bacterial groups were coagulase-negative staphylococci (CNS) 41.45 %( n=114), followed by Enterobacteriaceae 32.36 %( n=89).CNS were resistant to all beta-lactams in 57.89 %( n=66), and to glycopeptides in 5.26 %( n=6). Enterobacteriaceae were producers of extended-spectrum betalactamases in 79.77% (n=71) and producers of carbapenemases in 13.48% (n=12) of cases. The alarming increase of enterobacteriaceae isolates and their antibiotic resistance rates should encourage the reinforcement of hygiene measures in our University Hospital.

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