scholarly journals Comparison of the hemodynamic effects of sevoflurane anesthesia induction and maintenancevs TIVA in CABG surgery

1999 ◽  
Vol 46 (3) ◽  
pp. 240-246 ◽  
Author(s):  
Normand R. Gravel ◽  
Norman R. Searle ◽  
Jean Taillefer ◽  
Michel Carrier ◽  
Micheline Roy ◽  
...  



2021 ◽  
Vol 10 (4) ◽  
pp. 662
Author(s):  
Eun-Hee Kim ◽  
Young-Eun Jang ◽  
Sang-Hwan Ji ◽  
Ji-Hyun Lee ◽  
Sung-Ae Cho ◽  
...  

We investigated changes in plasma glial fibrillary acidic protein concentration during sevoflurane anesthesia induction in children < 3 years old and determined the effect of co-administering dexmedetomidine. This preliminary randomized trial included 60 pediatric patients who received sevoflurane anesthesia for >3 h. Patients were assigned to dexmedetomidine or control groups at a 1:1 ratio. The primary outcome was changes in plasma glial fibrillary acidic protein concentration of dexmedetomidine and control groups over time. Fifty-five patients were included in the final analysis. The median (interquartile range (IQR)) of the plasma glial fibrillary acidic protein level was 387.7 (298.9–510.8) pg·mL−1 immediately after anesthetic induction, 302.6 (250.9–412.5) pg·mL−1 at 30 min, and 321.9 (233.8–576.2) pg·mL−1 at 180 min after the first sample. These values did not change over time (p = 0.759). However, plasma glial fibrillary acidic protein increased after 180 min of infusion of dexmedetomidine compared with values at 30 min infusion (p = 0.04, mean difference and 95% confidence interval of 221.6 and 2.2 to 441.0 pg·mL−1). In conclusion, three hours of sevoflurane anesthesia in pediatric patients < 3 years old did not provoke neuronal injury assessed by the plasma biomarker. Further studies regarding the effect of prolonged dexmedetomidine infusion on anesthetic neuronal injury are required.



2017 ◽  
Vol 32 (1) ◽  
pp. 36
Author(s):  
Ju Deok Kim ◽  
Joo Won Kim ◽  
His Chiang Kung ◽  
Jun Hong Kang ◽  
Hye Young Shin ◽  
...  


1997 ◽  
Vol 33 (1) ◽  
pp. 63
Author(s):  
Ho Yeong Kil ◽  
Kwon Jae Lee ◽  
Seung Joon Lee ◽  
Young Joon Yoon


2014 ◽  
Vol 44 ◽  
pp. 317-322 ◽  
Author(s):  
Hasan Kutluk PAMPAL ◽  
Yusuf ÜNAL ◽  
Berrin IŞIK ◽  
Hatice Zerrin ÖZKÖSE ◽  
Recep Şahin YARDIM




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