The correlation between the oral glucose tolerance test 30-minutes plasma glucose and risk factors for diabetes and cardiovascular diseases: A cross-sectional epidemiological study of diabetes in Fujian Province in the South-East of China

2010 ◽  
Vol 34 (5) ◽  
pp. e115-e120
Author(s):  
G. Chen ◽  
X. Zou ◽  
J. Yao ◽  
Q. Jiang ◽  
Y. Zhang ◽  
...  
2012 ◽  
Vol 120 (1) ◽  
pp. 136-143 ◽  
Author(s):  
Erica P. Gunderson ◽  
Yvonne Crites ◽  
Vicky Chiang ◽  
David Walton ◽  
Robert A. Azevedo ◽  
...  

2020 ◽  
Vol 11 (6) ◽  
pp. 1520-1523
Author(s):  
Motonori Sato ◽  
Yoshifumi Tamura ◽  
Yuki Someya ◽  
Kageumi Takeno ◽  
Hideyoshi Kaga ◽  
...  

2013 ◽  
Vol 38 (12) ◽  
pp. 1254-1259 ◽  
Author(s):  
Adèle Coriati ◽  
Belinda Elisha ◽  
Sandrine Virassamynaik ◽  
Maude Phaneuf ◽  
Sophie Ziai ◽  
...  

Adult patients with cystic fibrosis (APCF) are at high risk of developing impaired glucose tolerance (IGT) and CF-related diabetes (CFRD) and thus an annual screening with a 2-h oral glucose tolerance test (OGTT) is recommended. This population would greatly benefit from a simplified and harmless alternative to the standard OGTT. Thus, we aimed to compare the diagnostic values of HbA1c and glycemias at interval time points during the 2-h OGTT for IGT and CFRD detection in APCF. To do so, we conducted a cross-sectional analysis of 194 APCF with normal fasting plasma glucose values (≤7.0 mmol·L−1) who underwent a 2-h OGTT. Receivers operating characteristic area under the curves (ROC-AUC) were analyzed to assess the diagnostic value of HbA1c and intermediate OGTT glycemias using 2-h OGTT glycemia as reference. For both IGT and CFRD diagnoses, ROC-AUC values obtained from glycemia at 90 min were significantly higher than HbA1c and remaining intermediate glycemias (p < 0.001). The best 90-min OGTT cut-off values for these diagnoses were >9.3 mmol·L−1 (IGT) and ≥11.5 mmol·L−1 (CFRD). A 90-min OGTT glycemia might be a simplified alternative to 2-h OGTT glycemia for earlier glucose tolerance abnormalities diagnosis in APCF. This finding should be confirmed in other APCF cohorts and its predictive value should be established prospectively.


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