scholarly journals Presence of Diabetic Complications in Type 1 Diabetic Patients Correlates with Low Expression of Mononuclear Cell AGE-Receptor-1 and Elevated Serum AGE

2001 ◽  
Vol 7 (3) ◽  
pp. 159-168 ◽  
Author(s):  
Ci-jiang He ◽  
Theodore Koschinsky ◽  
Christina Buenting ◽  
Helen Vlassara
Keyword(s):  
Mononuclear Cell ◽  
Diabetic Complications ◽  
Elevated Serum ◽  
Diabetic Patients ◽  
Cell Age ◽  
Type 1 Diabetic Patients ◽  
Low Expression

scholarly journals Risk Factors for Diabetic Complications in Juvenile-Onset Type 1 Diabetic Patients

2002 ◽  
Vol 11 (1) ◽  
pp. 55-65
Author(s):  
Taisuke Okada ◽  
Yasuko Uchigata ◽  
Hiroki Yokoyama ◽  
Takashi Tomoda ◽  
Yasuhiko Iwamoto
Keyword(s):  
Risk Factors ◽  
Diabetic Complications ◽  
Diabetic Patients ◽  
Juvenile Onset ◽  
Onset Type ◽  
Type 1 Diabetic Patients

Is there a relationship between body composition and insulin regimen modality in type 1 diabetic patients?

2014 ◽  
Author(s):  
Merve Yilmaz ◽  
Arzu Gedik ◽  
Simge Yilmaz ◽  
Belgin Bektas ◽  
Dilek Cimrin ◽  
...  
Keyword(s):  
Body Composition ◽  
Diabetic Patients ◽  
Insulin Regimen ◽  
Type 1 Diabetic Patients

Insulin-mimetic effects of short-term Rapamycin in type 1 diabetic patients prior islet transplantation

2017 ◽  
Author(s):  
Federica Ermetici ◽  
Silvia Briganti ◽  
Stefano Benedini ◽  
Roberto Codella ◽  
Paola Maffi ◽  
...  
Keyword(s):  
Islet Transplantation ◽  
Diabetic Patients ◽  
Short Term ◽  
Insulin Mimetic ◽  
Type 1 Diabetic Patients

Are fast insulin analogues fast enough? Switching to faster aspart may reduce glycemic variability and the risk of hypoglycemia in type 1 diabetic patients on sensor-augmented insulin pump therapy

2019 ◽  
Author(s):  
Manuel Esteban Nivelo-Rivadeneira ◽  
Agnieszka Kuzior ◽  
Paula Maria Fernandez-Trujillo-Comenge ◽  
Ana Delia Santana-Suarez ◽  
Carmen Acosta-Calero ◽  
...  
Keyword(s):  
Insulin Pump ◽  
Glycemic Variability ◽  
Insulin Analogues ◽  
Insulin Pump Therapy ◽  
Diabetic Patients ◽  
Pump Therapy ◽  
Type 1 Diabetic Patients ◽  
Fast Insulin

GENETIC ROLE OF HLA-G14 BASE PAIR INDEL POLYMORPHIC GENE WITH TYPE 1 DIABETIC PATIENTS

2019 ◽  
Vol 22 (09) ◽  
pp. 154-160
Author(s):  
Hasanain Khaleel Shareef ◽  
Ahmed Adil Ali ◽  
Rafah F. Al-Jebori
Keyword(s):  
Base Pair ◽  
Diabetic Patients ◽  
Polymorphic Gene ◽  
Type 1 Diabetic Patients

Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients

2001 ◽  
Vol 281 (5) ◽  
pp. E1029-E1036 ◽  
Author(s):  
Raymond R. Russell ◽  
Deborah Chyun ◽  
Steven Song ◽  
Robert S. Sherwin ◽  
William V. Tamborlane ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Radionuclide Angiography ◽  
Left Ventricular ◽  
Cardiac Response ◽  
Left Ventricular Ejection ◽  
Diabetic Patients ◽  
Plasma Catecholamine ◽  
Ventricular Ejection Fraction ◽  
Type 1 Diabetic Patients

Insulin-induced hypoglycemia occurs commonly in intensively treated patients with type 1 diabetes, but the cardiovascular consequences of hypoglycemia in these patients are not known. We studied left ventricular systolic [left ventricular ejection fraction (LVEF)] and diastolic [peak filling rate (PFR)] function by equilibrium radionuclide angiography during insulin infusion (12 pmol · kg−1 · min−1) under either hypoglycemic (∼2.8 mmol/l) or euglycemic (∼5 mmol/l) conditions in intensively treated patients with type 1 diabetes and healthy nondiabetic subjects ( n = 9 for each). During hypoglycemic hyperinsulinemia, there were significant increases in LVEF (ΔLVEF = 11 ± 2%) and PFR [ΔPFR = 0.88 ± 0.18 end diastolic volume (EDV)/s] in diabetic subjects as well as in the nondiabetic group (ΔLVEF = 13 ± 2%; ΔPFR = 0.79 ± 0.17 EDV/s). The increases in LVEF and PFR were comparable overall but occurred earlier in the nondiabetic group. A blunted increase in plasma catecholamine, cortisol, and glucagon concentrations occurred in response to hypoglycemia in the diabetic subjects. During euglycemic hyperinsulinemia, LVEF also increased in both the diabetic (ΔLVEF = 7 ± 1%) and nondiabetic (ΔLVEF = 4 ± 2%) groups, but PFR increased only in the diabetic group. In the comparison of the responses to hypoglycemic and euglycemic hyperinsulinemia, only the nondiabetic group had greater augmentation of LVEF, PFR, and cardiac output in the hypoglycemic study ( P < 0.05 for each). Thus intensively treated type 1 diabetic patients demonstrate delayed augmentation of ventricular function during moderate insulin-induced hypoglycemia. Although diabetic subjects have a more pronounced cardiac response to hyperinsulinemia per se than nondiabetic subjects, their response to hypoglycemia is blunted.

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