Hepatocyte growth factor in invasive growth of carcinomas

2007 ◽  
Vol 64 (11) ◽  
pp. 1341-1354 ◽  
Author(s):  
M. A. Desiderio
2014 ◽  
Vol 1033-1034 ◽  
pp. 224-228
Author(s):  
Yan Xia Sun ◽  
Guang Yu Zhou ◽  
Li Li ◽  
Xue Mei Han

To investigate the effect of geldanamycin (GDM) on the invasion ability of glioma cell induced by hepatocyte growth factor (HGF). Malignant glioma cell line U251-MG and U87-MG were cultured’and the capability of cell invasion was detected using a Transwell culture system. HGF significantly promoted the invasion ability of both U251-MG and U87-MG cells as compared with the normal control (NC) (P < 0.05). Forty eight hours after GDM treatment, the invasive growth of glioma cells was significantly decreased as compared with either NC or HGF group (P < 0.05). When cells were exposed to GDM plus HGF for 48 h, the cell invasion capability was greatly reduced as compared with either NC or HGF group (P < 0.05). The number of invaded cells in GDM plus HGF group was similar to that of GDM group.GDM can inhibit the invasion ability of glioma cells induced by HGF.


2006 ◽  
Vol 18 (11) ◽  
pp. 1967-1976 ◽  
Author(s):  
Michela Fassetta ◽  
Lorenza D'Alessandro ◽  
Nadia Coltella ◽  
Maria Flavia Di Renzo ◽  
Andrea Rasola

2005 ◽  
Vol 118 (3) ◽  
pp. 583-592 ◽  
Author(s):  
Shunro Uchinokura ◽  
Shiro Miyata ◽  
Tsuyoshi Fukushima ◽  
Hiroshi Itoh ◽  
Shinichi Nakano ◽  
...  

Pneumologie ◽  
2014 ◽  
Vol 68 (06) ◽  
Author(s):  
S Skwarna ◽  
I Henneke ◽  
W Seeger ◽  
T Geiser ◽  
A Günther ◽  
...  

Diabetes ◽  
1997 ◽  
Vol 46 (1) ◽  
pp. 138-142 ◽  
Author(s):  
R. Morishita ◽  
S. Nakamura ◽  
Y. Nakamura ◽  
M. Aoki ◽  
A. Moriguchi ◽  
...  

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