Congestive heart failure caused by silent ischemia and silent myocardial infarction

Herz ◽  
2019 ◽  
Vol 44 (3) ◽  
pp. 210-217 ◽  
Author(s):  
P. Valensi ◽  
C. Meune
2020 ◽  
Vol 9 (8) ◽  
pp. 931-938 ◽  
Author(s):  
Mattias Skielta ◽  
Lars Söderström ◽  
Solbritt Rantapää-Dahlqvist ◽  
Solveig W Jonsson ◽  
Thomas Mooe

Aims: Rheumatoid arthritis may influence the outcome after an acute myocardial infarction. We aimed to compare trends in one-year mortality, co-morbidities and treatments after a first acute myocardial infarction in patients with rheumatoid arthritis versus non-rheumatoid arthritis patients during 1998–2013. Furthermore, we wanted to identify characteristics associated with mortality. Methods and results: Data for 245,377 patients with a first acute myocardial infarction were drawn from the Swedish Register of Information and Knowledge about Swedish Heart Intensive Care Admissions for 1998–2013. In total, 4268 patients were diagnosed with rheumatoid arthritis. Kaplan-Meier analysis was used to study mortality trends over time and multivariable Cox regression analysis was used to identify variables associated with mortality. The one-year mortality in rheumatoid arthritis patients was initially lower compared to non-rheumatoid arthritis patients (14.7% versus 19.7%) but thereafter increased above that in non-rheumatoid arthritis patients (17.1% versus 13.5%). In rheumatoid arthritis patients the mean age at admission and the prevalence of atrial fibrillation increased over time. Congestive heart failure decreased more in non-rheumatoid arthritis than in rheumatoid arthritis patients. Congestive heart failure, atrial fibrillation, kidney failure, rheumatoid arthritis, prior diabetes mellitus and hypertension were associated with significantly higher one-year mortality during the study period 1998–2013. Conclusions: The decrease in one-year mortality after acute myocardial infarction in non-rheumatoid arthritis patients was not applicable to rheumatoid arthritis patients. This could partly be explained by an increased age at acute myocardial infarction onset and unfavourable trends with increased atrial fibrillation and congestive heart failure in rheumatoid arthritis. Rheumatoid arthritis per se was associated with a significantly worse prognosis.


Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Scott Mu ◽  
Caitlin W Hicks ◽  
Natalie R Daya ◽  
Randi E Foraker ◽  
Anna Kucharska-newton ◽  
...  

Introduction: Hospitalization is a complex health exposure and the period immediately following acute-care hospitalization is a high-risk state. Self-rated health is a subjective indicator of health and the long-term trends in self-rated health after hospitalization are not well characterized. Hypotheses: 1. Self-rated health decreases after hospitalization, with only partial recovery in the following years. 2. Poor self-rated health after hospitalization is associated with increased mortality. Methods: We analyzed 13,758 participants in the Atherosclerosis Risk in Communities (ARIC) Study with at least 1 hospitalization. Self-rated health was assessed annually and rated on a 4-point scale as follows: “Over the past year, compared to other people your age, would you say that your health has been excellent(=4), good(=3), fair(=2) or poor(=1)?" Using Cox regression and Kaplan-Meier methods, we evaluated mortality after hospitalization for myocardial infarction, congestive heart failure, cerebrovascular disease, pneumonia or diabetes mellitus with complications. Results: The mean self-rated health the year prior to hospitalization was 2.82 and the nadir of self-rated health was 2.62, occurring 1 year after hospitalization (Fig 1a). As compared to “excellent” self-rated health, “poor” self-rated health after any hospitalization was strongly associated with mortality (HR 4.65, 95% CI 4.27-5.07). Corresponding HRs (95% CI) for mortality post-hospitalization were 3.12 (2.30-4.22) for acute myocardial infarction, 3.08 (2.39-3.96) for congestive heart failure, 2.15 (1.43-3.23) for acute cerebrovascular disease, 4.54 (3.39-6.09) for pneumonia, and 3.32 (2.35-4.69) for diabetes mellitus with complications (Fig 1b). Conclusion: Mean self-rated health decreases significantly after hospitalization and worse self-rated health is associated with higher mortality. Self-rated health is an easily obtained patient centered outcome with valuable prognostic information.


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