R3-Survey of traumatic brain injury management in European Brain IT centres year 2001

2004 ◽  
Vol 30 (6) ◽  
pp. 1058-1065 ◽  
Author(s):  
P. Enblad ◽  
P. Nilsson ◽  
I. Chambers ◽  
G. Citerio ◽  
H. Fiddes ◽  
...  
2014 ◽  
Vol 5 (4) ◽  
pp. 245 ◽  
Author(s):  
Kou Kou ◽  
Xiang-yu Hou ◽  
Jian-dong Sun ◽  
Kevin Chu

2018 ◽  
pp. 83-96
Author(s):  
Jeremy G. Stone ◽  
David M. Panczykowski ◽  
David O. Okonkwo

The management of traumatic brain injury necessitates a multidisciplinary approach with medical and surgical therapies employed based on rapid clinical assessment of injury severity and imaging characteristics. Therapy aims to prevent secondary brain injury through multifactorial interventions primarily focusing on prevention of cerebral hypoxemia and aggressive control of intracranial pressure (ICP). This chapter covers epidemiology, pathophysiology, clinical assessment, and both medical and surgical management of traumatic brain injury. Management topics include appropriate monitoring, first- and second-line therapy for ICP and cerebral perfusion pressure, hypoxia, seizure prophylaxis, hyperpyrexia, glycemic control, fluids and electrolytes, nutrition, and prophylaxis for venous thromboembolism and the gastrointestinal system.


2017 ◽  
Vol 31 (3) ◽  
pp. 319-334
Author(s):  
Hector Rolando Romero-Rivera ◽  
Marticela Cabeza-Morales ◽  
Enrique Soto-Zarate ◽  
Guru Dutta Satyarthee ◽  
Huber Padilla-Zambrano ◽  
...  

Abstract Oxidative stress constitute one of the commonest mechanism of the secondary injury contributing to neuronal death in traumatic brain injury cases. The oxidative stress induced secondary injury blockade may be considered as to be a good alternative to improve the outcome of traumatic brain injury (TBI) treatment. Due to absence of definitive therapy of traumatic brain injury has forced researcher to utilize unconventional therapies and its roles investigated in the improvement of management and outcome in recent year. Antioxidant therapies are proven effective in many preclinical studies and encouraging results and the role of antioxidant mediaction may act as further advancement in the traumatic brain injury management it may represent aonr of newer moadlaity in neurosurgical aramamentorium, this kind of therapy could be a good alternative or adjuct to the previously established neuroprotection agents in TBI.


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