Neutrophil-to-lymphocyte ratio (NLR) distribution shows a better kinetic pattern than C-reactive protein distribution for the follow-up of early inflammation after total knee arthroplasty

2015 ◽  
Vol 24 (10) ◽  
pp. 3287-3292 ◽  
Author(s):  
J. C. Yombi ◽  
P. E. Schwab ◽  
E. Thienpont
2016 ◽  
Vol 18 (3) ◽  
pp. 283-287 ◽  
Author(s):  
Tyler Barker ◽  
Victoria E. Rogers ◽  
Kimberly B. Brown ◽  
Vanessa T. Henriksen ◽  
G. Lynn Rasmussen

2016 ◽  
Vol 24 (10) ◽  
pp. 3163-3167 ◽  
Author(s):  
Christoph Windisch ◽  
Steffen Brodt ◽  
Eric Roehner ◽  
Georg Matziolis

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Jun Ho Nam ◽  
Myung Rae Cho ◽  
Seo Ho Lee ◽  
Suk-Kyoon Song ◽  
Won-Kee Choi

Abstract Purpose The purpose is to estimate the degree of normalization of C-reactive protein (CRP) at 2 weeks and 4 weeks after uncomplicated total knee arthroplasty (TKA) using computer navigation. We also wish to determine whether the degree of normalization of CRP at 2 and 4 weeks differs after TKA performed in one knee and after TKA performed sequentially in both knees. We also want to analyze the patient factors that may influence the normalization of CRP. Material and methods We studied 400 knees who underwent primary computer-navigated TKA for treatment of advanced osteoarthritis: the TKAs were all performed by the same surgeon. We retrospectively analyzed CRP levels during the preoperative period, the early postoperative period (5–7 days), the 2-week postoperative period (12–14 days), and the 4-week postoperative period (25–30 days). We have assumed gender, age, body mass index (BMI), staged bilateral TKA, and preoperative CRP as the potential patient factors associated with CRP normalization. Results In unilateral TKA, CRP was normalized in 94 cases (34.3%) and in 219 cases (81.4%) within 2 weeks and 4 weeks after surgery, respectively. In second-knee, staged bilateral TKA, CRP was normalized in 46 cases (35.1%) and in 104 cases (79.4%) within 2 weeks and 4 weeks after surgery, respectively. There were no statistical differences between unilateral TKA and second-knee, staged bilateral TKA during the 2-week postoperative and the 4-week postoperative period. Compared to women, men were 1.99 times less likely to have normalized CRP at 2 weeks after surgery (P = 0.02). Conclusion CRP was less likely to normalize during the 2-week postoperative period in men than it is in women, while there was no difference between men and women in the normalization of CRP during the 4-week postoperative period. There were no statistical differences in the course of CRP levels after unilateral TKA and staged bilateral TKA during the 2-week postoperative and the 4-week postoperative period.


2017 ◽  
Vol 52 (2) ◽  
pp. 176-181
Author(s):  
João Maurício Barretto ◽  
Fabrício Bolpato Loures ◽  
Rodrigo Sattamini Pires e Albuquerque ◽  
Filipe das Neves Bezerra ◽  
Rafael Vinagre Faro ◽  
...  

2020 ◽  
Vol 26 (2) ◽  
pp. 87-91
Author(s):  
Shalin Shah ◽  
Christopher Brown ◽  
John Owen ◽  
Bernard Fisher ◽  
Ramesh Natarajan ◽  
...  

Background: Vitamin C levels are decreased in arthritis patients and reduced levels following surgery may impair adequate healing. Aim: This study measured changes in vitamin C and inflammatory markers in patients undergoing total knee arthroplasty (TKA). Methods: Venous blood samples were collected from 10 patients during the preoperative to postoperative period. Vitamin C, interleukin-1 β, interleukin-6 (IL-6), and C-reactive protein (CRP) levels were measured using various assays. Results: No significant changes in vitamin C levels were measured. However, all participants had suboptimal preoperative vitamin C levels and 90% had suboptimal levels postoperatively. IL-6 and CRP levels significantly increased during the immediate postoerative period. Conclusion: There was a rise in inflammation following TKA while vitamin C levels did not significantly change during this short study period. Of note, every patient had suboptimal vitamin C levels prior to surgery and 90% continued with suboptimal levels two days postoperatively.


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