Electrophoretic deposition of PEEK/bioactive glass composite coatings on stainless steel for orthopedic applications: an optimization for in vitro bioactivity and adhesion strength

Three different glasses were synthesized by doping 45S5 bioactive glass with B2O3. The bioactivity of the glasses was evaluated by immersion in simulated body fluid (SBF) up to 3 days; all glasses showed the precipitation of hydroxyapatite (HAp) after one day of soaking in SBF. Electrophoretic deposition (EPD) was used to prepare PEEK/B2O3-doped 45S5 glass composite coatings on stainless steel substrates. The coatings were characterized by means of tape test (ASTM D3359-B), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), contact angle measurements, thermogravimetric analysis and in vitro bioactivity test. All composite coatings exhibited a porous and homogenous structure with a hydrophobic surface, according to the wettability test. The in vitro test in SBF demonstrated that the coatings were highly bioactive.

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Synthesis and Characterization of Silver–Strontium (Ag-Sr)-Doped Mesoporous Bioactive Glass Nanoparticles

Gels ◽

10.3390/gels7020034 ◽

2021 ◽

Vol 7 (2) ◽

pp. 34

Author(s):

Shaher Bano ◽

Memoona Akhtar ◽

Muhammad Yasir ◽

Muhammad Salman Maqbool ◽

Akbar Niaz ◽

...

Keyword(s):

Bioactive Glass ◽

Composite Coatings ◽

Antibacterial Properties ◽

Bone Diseases ◽

Osteogenic Potential ◽

Diffusion Method ◽

Charge Composition ◽

In Vitro Bioactivity ◽

Mesoporous Bioactive Glass

Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc., are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag)- and strontium (Sr)-doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ and Sr2+ were co-substituted in pure MBGNs to harvest the antibacterial properties of Ag ions, as well as pro-osteogenic potential of Sr2 ions. The effect of the two-ion concentration on morphology, surface charge, composition, antibacterial ability, and in-vitro bioactivity was studied. Scanning electron microscopy (SEM), X-Ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) confirmed the doping of Sr and Ag in MBGNs. SEM and EDX analysis confirmed the spherical morphology and typical composition of MBGNs, respectively. The Ag-Sr MBGNs showed a strong antibacterial effect against Staphylococcus carnosus and Escherichia coli bacteria determined via turbidity and disc diffusion method. Moreover, the synthesized Ag-Sr MBGNs develop apatite-like crystals upon immersion in simulated body fluid (SBF), which suggested that the addition of Sr improved in vitro bioactivity. The Ag-Sr MBGNs synthesized in this study can be used for the preparation of scaffolds or as a filler material in the composite coatings for bone tissue engineering.

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Electrophoretic deposition of nanostructured TiO2/alginate and TiO2-bioactive glass/alginate composite coatings on stainless steel

Advances in Applied Ceramics ◽

10.1179/1743676113y.0000000096 ◽

2013 ◽

Vol 113 (1) ◽

pp. 42-49 ◽

Cited By ~ 27

Author(s):

L. Cordero-Arias ◽

S. Cabanas-Polo ◽

J. Gilabert ◽

O. M. Goudouri ◽

E. Sanchez ◽

...

Keyword(s):

Stainless Steel ◽

Bioactive Glass ◽

Electrophoretic Deposition ◽

Composite Coatings ◽

Nanostructured Tio2

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Electrophoretic deposition of chondroitin sulfate-chitosan/bioactive glass composite coatings with multilayer design

Surface and Coatings Technology ◽

10.1016/j.surfcoat.2017.02.037 ◽

2017 ◽

Vol 315 ◽

pp. 417-425 ◽

Cited By ~ 9

Author(s):

L. Cordero-Arias ◽

A.R. Boccaccini

Keyword(s):

Bioactive Glass ◽

Chondroitin Sulfate ◽

Electrophoretic Deposition ◽

Composite Coatings ◽

Glass Composite ◽

Multilayer Design

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Electrophoretic Deposition and Characterization of Chitosan/45S5 Bioactive Glass Composite Coatings on Porous Titanium for Biomedical Applications

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.654.189 ◽

2015 ◽

Vol 654 ◽

pp. 189-194 ◽

Cited By ~ 8

Author(s):

S. Borjas ◽

E.J. Gil ◽

L. Cordero ◽

J.J. Pavón ◽

J.A. Rodriguez-Ortiz ◽

...

Keyword(s):

Bioactive Glass ◽

Electrophoretic Deposition ◽

Composite Coatings ◽

High Vacuum ◽

Processing Parameters ◽

Porous Titanium ◽

Glass Composite ◽

Set Up ◽

Titanium Structure

Porous titanium samples of cp Ti grade IV were obtained by space-holder technique (50%vol of NH4HCO3, 800 MPa, 1250 oC during 2h in high vacuum), producing a good balance between stiffness and mechanical strength. The samples were coated with chitosan/45S5 bioactive glass composite by electrophoretic deposition. Homogeneity, infiltration efficiency, and coatings integrity (cracking and adhesion) were evaluated in order to establish correlations with processing parameters. SEM, FTIR, and contact profilometry were performed for detailed characterization of the coatings; and micro-mechanical properties (P-h curves and scratch testing) were set-up as well. Optimum EPD parameters were 25V, 7 min and suspension containing 0.5 g/L chitosan and 1.5 g/L BG a titanium structure with pore sizes greater than 200 μm are required.

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Synthesis and Characterization of Silver–Strontium (Ag-Sr) Doped Mesoporous Bioactive Glass Nanoparticles

10.20944/preprints202102.0245.v1 ◽

2021 ◽

Author(s):

Shaher Bano ◽

Memoona Akhtar ◽

Muhammad Yasir ◽

Muhammad Salman Maqbool ◽

Akbar Niaz ◽

...

Keyword(s):

Bioactive Glass ◽

Composite Coatings ◽

Antibacterial Properties ◽

Bone Diseases ◽

Osteogenic Potential ◽

Diffusion Method ◽

Charge Composition ◽

In Vitro Bioactivity ◽

Mesoporous Bioactive Glass

Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc. are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag) and strontium (Sr) doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ & Sr2+ were co-substituted in pure MBGNs to harvest the antibacterial properties of Ag ions, as well as pro-osteogenic potential of Sr2 ions. The effect of the two ion concentration on morphology, surface charge, composition, antibacterial ability, and in-vitro bioactivity was studied. Scanning electron microscopy (SEM), X-Ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) confirmed the doping of Sr and Ag in MBGNs. SEM and EDX analysis confirmed the spherical morphology and typical composition of MBGNs, respectively. The Ag-Sr MBGNs showed a strong antibacterial effect against Staphylococcus carnosus and Escherichia coli bacteria determined via turbidity and disc diffusion method. Moreover, the synthesized Ag-Sr MBGNs develop apatite-like crystals upon immersion in simulated body fluid (SBF), which suggested that the addition of Sr improved in-vitro bioactivity. The Ag-Sr MBGNs synthesize in this study can be used for the preparation of scaffolds or as a filler material in the composite coatings for bone tissue engineering.

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