This paper reports on the speciation of heavy metals (Cd, Pb, Cr, Cu, Ni, Mn, Fe, and Zn) in the surface water dissolvedfraction of the low basin and plume of the Manzanares River, in the state of Sucre, Venezuela, based on data taken at 22 stationsfrom July 1996 to June 1997. The total metal concentrations in the dissolved phase ranged from below detection levels to 0.01,0.02, 0.02, 0.10, 0.10, 1.03, 2.56, and 5.13 μmol L–1 for Cd, Pb, Cr, Cu, Ni, Mn, Fe, and Zn, respectively. Overall, the metalsstudied revealed a nonconservative behavior with removal at low salinities, likely due to anthropogenic contributions and toflocculation on account of Fe- and Mn-oxyhydroxide formation resulting from the shifts in pH and ion forces that ensue whenthe fresh waters of the river meet the marine water mass of the Gulf of Cariaco. The heavy metals in the dissolved fraction, inboth free and hydrated form, had a composition in which the largest proportions were associated with humic acids, thus beingmore readily available to organisms.