Mechanism and kinetics of the hydroxyl and hydroperoxyl radical scavenging activity of N-acetylcysteine amide

2011 ◽  
Vol 130 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Annia Galano
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Hydroperoxyl Radical ◽  
Mechanism And Kinetics ◽  
Kinetics Of

Insights into the mechanisms and kinetics of the hydroperoxyl radical scavenging activity of Artepillin C

2021 ◽  
Author(s):  
Houssem Boulebd ◽  
Adam Mechler ◽  
Nguyen Thi Hoa ◽  
Pham Cam Nam ◽  
Duong Tuan Quang ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Single Electron ◽  
Scavenging Activity ◽  
Single Electron Transfer ◽  
Hydroperoxyl Radical ◽  
Electron Transfer Mechanism ◽  
Artepillin C ◽  
Kinetics Of

Through the single electron transfer mechanism, Artepillin C scavenges the hydroperoxyl radical in water approximately 572 times faster than Trolox.

Degradation kinetics of some phenolic compounds in subcritical water and radical scavenging activity of their degradation products

2013 ◽  
Vol 92 (5) ◽  
pp. 810-815 ◽  
Author(s):  
Pramote Khuwijitjaru ◽  
Jiraporn Plernjit ◽  
Boonyanuch Suaylam ◽  
Suched Samuhaseneetoo ◽  
Rungnaphar Pongsawatmanit ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Subcritical Water ◽  
Degradation Products ◽  
Degradation Kinetics ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Kinetics Of

scholarly journals Theoretical insights into the antiradical activity and copper-catalysed oxidative damage of mexidol in the physiological environment

2022 ◽  
Vol 9 (1) ◽  
Author(s):  
Nguyen Thi Hoa ◽  
Mai Van Bay ◽  
Adam Mechler ◽  
Quan V. Vo
Keyword(s):  
Oxidative Damage ◽  
Chemical Structure ◽  
Hydrogen Transfer ◽  
Therapeutic Agent ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reduction Reaction ◽  
Scavenging Activity ◽  
Hydroperoxyl Radical ◽  
Transfer Mechanisms

Mexidol ( MD , 2-ethyl-6-methyl-3-hydroxypyridine) is a registered therapeutic agent for the treatment of anxiety disorders. The chemical structure suggests that MD may also act as an antioxidant. In this study, the hydroperoxyl radical scavenging activity of MD was studied to establish baseline antioxidant activity, followed by an investigation of the effect of MD on the copper-catalysed oxidative damage in biological systems, using computational methods. It was found that MD exhibits moderate radical scavenging activity against HOO • in water and pentyl ethanoate solvents following the single electron transfer and formal hydrogen transfer mechanisms, respectively. MD can chelate Cu(II), forming complexes that are much harder to reduce than free Cu(II): MD chelation completely quenches the Cu(II) reduction by ascorbic acid and suppresses the rate of reduction reaction by O 2 ⋅ − that are the main reductants of Cu(II) in biological environments. Therefore, MD exerts its anti-HO • activity primarily as an OIL-1 inhibitor.

Kinetics of the lipoperoxyl radical-scavenging activity of indicaxanthin in solution and unilamellar liposomes

2007 ◽  
Vol 41 (2) ◽  
pp. 226-233 ◽  
Author(s):  
L. Tesoriere ◽  
M. Allegra ◽  
D. Butera ◽  
C. Gentile ◽  
M. A. Livrea
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Kinetics Of
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