A method for the simultaneous quantification of eight metabolites of synthetic pyrethroids in urine of the general population using gas chromatography-tandem mass spectrometry

2016 ◽  
Vol 408 (20) ◽  
pp. 5467-5478 ◽  
Author(s):  
Thomas Schettgen ◽  
Petra Dewes ◽  
Thomas Kraus
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
General Population ◽  
Tandem Mass Spectrometry ◽  
Synthetic Pyrethroids ◽  
Tandem Mass ◽  
Simultaneous Quantification ◽  
Chromatography Tandem Mass Spectrometry

Analysis of Numerous Androgen Disruptors in Fish by Gas Chromatography Tandem Mass Spectrometry

2017 ◽  
Vol 100 (3) ◽  
pp. 647-652 ◽  
Author(s):  
Shaoying Liu ◽  
Tianbin Bian ◽  
Huali He ◽  
Huang Huang ◽  
Quan Jin ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Tandem Mass Spectrometry ◽  
Analytical Method ◽  
Tandem Ms ◽  
Tandem Mass ◽  
Simultaneous Quantification ◽  
Chromatography Tandem Mass Spectrometry ◽  
Target Analytes ◽  
Fish Samples

Abstract An improved analytical method was developed for the simultaneous quantification of numerous androgen disruptors—vinclozolin, dichlorodiphenyltrichloroethanes (DDTs), hexachlorocyclohexanes, chlordane, heptachlor, dieldrin, endrin, and aldrin—in fish, followed by GC with tandem MS (MS/MS). Extraction, cleanup, and MS/MS parameters of analytes were optimized. The LOQs of the analytes ranged from 0.3 to 3.7 μg/kg. Reasonable recoveries (73.7–119.2%) were demonstrated at different spike levels with RSDs lower than 12.2%. This method was applied for the analysis of the target analytes in fish samples sold in Hangzhou, China, and DDTs were found to be the predominant contaminants in fish samples.

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