Age-Related Three-Dimensional Microarchitectural Adaptations of Subchondral Bone Tissues in Guinea Pig Primary Osteoarthrosis

Burgos and Wislocki described changes in the mucosa of the guinea pig uterus, cervix and vagina during the estrous cycle investigated by transmission electron microscopy. More recently, Moghissi and Reame reported the effects of progestational agents on the human female reproductive tract. They found drooping and shortening of cilia in norgestrel and norethindrone- treated endometria. To the best of our knowledge, no studies concerning the effects of mestranol and norethindrone given concurrently on the three-dimensional surface features on the uterine mucosa of the guinea pig have been reported. The purpose of this study was to determine the effect of mestranol and norethindrone on surface ultrastructure of guinea pig uterus by SEM.Seventy eight animals were used in this study. They were allocated into two groups. Group 1 (20 animals) was injected intramuscularly 0.1 ml vegetable oil and served as controls.

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Relationship between potency of L-isoprenaline and β-adrenoceptor density estimated in single cells from tracheal smooth muscles of guinea pigs of different ages

Canadian Journal of Physiology and Pharmacology ◽

10.1139/y92-059 ◽

1992 ◽

Vol 70 (4) ◽

pp. 458-461 ◽

Cited By ~ 2

Author(s):

Issei Takayanagi ◽

Mitsutoshi Satoh ◽

Noriko Kokubu ◽

Teruko Kato

Keyword(s):

Guinea Pig ◽

Guinea Pigs ◽

Dissociation Constants ◽

Specific Binding ◽

Single Cells ◽

Regression Line ◽

Smooth Muscles ◽

Receptor Density ◽

Age Related ◽

Β Receptor

An age-related change in potency of L-isoprenaline in the presence of ascorbic acid, desmethylimipramine, corticosterone, pargyline, and phentolamine was obtained in tracheal strips from guinea pigs of differing ages between 6 and 40 weeks. The potency in the strips from 100-week-old guinea pigs did not significantly differ from that in strips from 40-week-old animals. Single cells were prepared from the tracheal muscles of 6-, 10-, 40-, and 100-week-old guinea pigs. The specific binding of [3H]dihydroalprenolol to the single cells was saturable. The dissociation constants of [3H]dihydroalprenolol were in good agreement with those of the membrane fractions from the guinea-pig tracheal muscles, and did not change with age. An excellent relationship between the potency of L-isoprenaline and the maximum binding of [3H]dihydroalprenolol estimated in the preparations from 6- to 40-week-old guinea pigs was found, suggesting that the increase in the potency of L-isoprenaline is due to the increase in the maximum binding or receptor density. The value in the preparations from 100-week-old guinea pigs deviated significantly from the regression line. This suggests the possibility that the decrease in potency in the strips from 100-week-old animals is due to a change in post β-receptor processes in responsiveness.Key words: guinea-pig trachea, single cells, β-receptor density, ageing, dissociation constant.

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Computer-aided Three-dimensional Reconstruction of Guinea Pig Cochlear Aqueduct

Acta Oto-Laryngologica ◽

10.3109/00016489109138430 ◽

1991 ◽

Vol 111 (5) ◽

pp. 917-920 ◽

Cited By ~ 5

Author(s):

Ryuzo Toriya ◽

Toshio Arima ◽

Akio Kuraoka ◽

Takuya Uemura

Keyword(s):

Guinea Pig ◽

Three Dimensional ◽

Three Dimensional Reconstruction ◽

Cochlear Aqueduct ◽

Computer Aided ◽

Dimensional Reconstruction

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Age-Related Differences in Throwing Techniques Used by the Catcher in Baseball

Pediatric Exercise Science ◽

10.1123/pes.6.3.225 ◽

1994 ◽

Vol 6 (3) ◽

pp. 225-235 ◽

Cited By ~ 3

Author(s):

Shinji Sakurai ◽

Bruce Elliott ◽

J. Robert Grove

Keyword(s):

High Speed ◽

High Performance ◽

Age Groups ◽

Three Dimensional ◽

Transformation Method ◽

High Speed Photography ◽

Two Phase ◽

Ball Speed ◽

Age Related ◽

Release Speed

Three-dimensional (3-D) high speed photography was used to record the overarm throwing actions of five open-age, four 18-year-old, six 16-year- old, and six 14-year-old high-performance baseball catchers. The direct linear transformation method was used for 3-D space reconstruction from 2-D images of the catchers throwing from home plate to second base recorded using two phase-locked cameras operating at a nominal rate of 200 Hz. Selected physical capacity measures were also recorded and correlated with ball release speed. In general, anthropometric and strength measures significantly increased through the 14-year-old to open-age classifications, while a range of correlation coefficients from .50 to .84 was recorded between these physical capacities and ball speed at release. While many aspects of the kinematic data at release were similar, the key factors of release angle and release speed varied for the different age groups.

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