Neonate With Vein of Galen Malformation and Heart Failure: Serial Changes in Plasma B-Type Natriuretic Peptide Following Endovascular Embolization

2006 ◽  
Vol 27 (2) ◽  
pp. 276-278 ◽  
Author(s):  
L.H. Tan ◽  
B.A. Johnson ◽  
M.E. Mawad ◽  
A.C. Chang
Keyword(s):  
Heart Failure ◽  
Natriuretic Peptide ◽  
Endovascular Embolization ◽  
Vein Of Galen ◽  
Vein Of Galen Malformation

Successful Surgical and Anesthetic Management of Vein of Galen Aneurysm in a Neonate in Congestive Heart Failure

Neurosurgery ◽  
1988 ◽  
Vol 22 (5) ◽  
pp. 908-910 ◽  
Author(s):  
Jane Matjasko ◽  
Walker Robinson ◽  
Daniel Eudaily
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Cardiac Failure ◽  
Growth And Development ◽  
Anesthetic Management ◽  
Vascular Supply ◽  
Vein Of Galen ◽  
Vein Of Galen Malformation ◽  
Vein Of Galen Aneurysm

Abstract A 12-day-old infant in intractable cardiac failure due to a vein of Galen malformation was treated successfully with serial ligation of the majority of the vessels feeding the malformation. Despite some residual vascular supply to the malformation, the congestive heart failure has disappeared and growth and development have been normal over a 3-year follow-up period.

Fistulous-type vein of Galen malformation phantom model for endovascular training and research

2016 ◽  
Vol 9 (9) ◽  
pp. 880-886
Author(s):  
Dan Meila ◽  
Katharina Melber ◽  
Dominik Grieb ◽  
Collin Jacobs ◽  
Heinrich Lanfermann ◽  
...  
Keyword(s):  
Treatment Options ◽  
Endovascular Embolization ◽  
High Flow ◽  
Vein Of Galen ◽  
Vein Of Galen Malformation ◽  
Phantom Model ◽  
Before And After ◽  
And Training

IntroductionVein of Galen malformation (VGM), a high-flow intracranial arteriovenous shunt, is among the most severe neurovascular diseases in childhood. In many cases untreated children die or survive only severely disabled. Endovascular embolization is the preferred treatment.ObjectiveTo develop a simple fistulous-type VGM phantom model for teaching and training of different endovascular treatment methods and to investigate new treatment options and devices.MethodsAn experimental in vitro pulsatile phantom model was developed imitating a high-flow fistulous-type VGM, which is typical, especially in the neonatal phase. Pressure measurements at different arterial sites were performed before and after closure of the VGM. Closure of the VGM was achieved by coiling using a combined microcatheter-based transvenous and transarterial approach called ‘kissing microcatheter technique’.ResultsThe behaviour of the phantom model in vitro under fluoroscopy and under angiographic runs was extremely similar to that in in vivo conditions in children. The results showed that intra-arterial pressures changed and increased statistically significantly at all measurement sites after embolization, as in human arteriovenous malformation. We also demonstrated different and complementary visualizations of hemodynamics and angioarchitecture by antegrade and retrograde microcatheter injections.ConclusionsOur phantom model behaves like a typical fistulous-type VGM and can be used in vitro for teaching and training and for further research. It offers a new and better understanding of hemodynamics and angioarchitecture in the endovascular management of VGM.

scholarly journals Vein of Galen malformation, a rare cause of epilepsy

2016 ◽  
Vol 03 (01) ◽  
pp. 024-025
Author(s):  
Mohammad Sayadnasiri
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Vascular Malformation ◽  
Neonatal Period ◽  
Severe Congestive Heart Failure ◽  
Low Flow ◽  
Vein Of Galen ◽  
Vein Of Galen Malformation ◽  
Venous Structure ◽  
Cerebral Vascular Malformation

AbstractVein of Galen malformation (VOGM) is a rare congenital cerebral vascular malformation characterized by an aneurysmally dilated midline deep venous structure, fed by abnormal arteriovenous communication. Most patients develop severe congestive heart failure at neonatal period that is fatal if left untreated. Rarely, patients with low-flow fistula present with headache, seizure, or focal neurological sign at adulthood. A 28-year-old female with VOGM-related epilepsy was introduced in this brief report.

scholarly journals Vein of Galen malformation

2009 ◽  
Vol 27 (5) ◽  
pp. E8 ◽  
Author(s):  
Stanley Hoang ◽  
Omar Choudhri ◽  
Michael Edwards ◽  
Raphael Guzman
Keyword(s):  
Poor Prognosis ◽  
Pediatric Population ◽  
Vascular Lesion ◽  
Endovascular Embolization ◽  
Vein Of Galen ◽  
Vein Of Galen Malformation ◽  
Developmental Mechanisms

A vein of Galen malformation is a rare intracranial vascular lesion affecting the pediatric population. Its poor prognosis has been significantly improved with the development of endovascular embolization. In this paper the authors review the developmental mechanisms, clinical pathophysiology, and the available data on the management and outcome of the disease.

Vein of Galen malformation presenting as congestive heart failure

2015 ◽  
Vol 08 (04) ◽  
pp. 437-439
Author(s):  
Vinod Maller ◽  
Veena Chowdhury ◽  
Vivek Kottiyath ◽  
Girish Khandelwal ◽  
Rajat Jain ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Vein Of Galen ◽  
Vein Of Galen Malformation

scholarly journals Targeted Neonatal Echocardiography-Guided Therapy in Vein of Galen Aneurysmal Malformation: A Report of Two Cases with a Review of Physiology and Approach to Management

2019 ◽  
Vol 09 (02) ◽  
pp. e172-e176 ◽  
Author(s):  
R. E. Giesinger ◽  
Y. N. Elsayed ◽  
M. P. Castaldo ◽  
P. J. McNamara
Keyword(s):  
Ductus Arteriosus ◽  
Endovascular Embolization ◽  
Vein Of Galen ◽  
Vein Of Galen Malformation ◽  
Systemic Blood ◽  
Systemic Blood Flow ◽  
Ventricular Performance ◽  
Right Ventricular Performance ◽  
Neonatal Echocardiography ◽  
Guided Therapy

AbstractVein of Galen malformation results in predictable changes in physiology which exist on a continuum. Severe pulmonary hypertension may present as hypoxemia; however, excessive reduction in pulmonary vascular resistance may precipitate progressive pulmonary overcirculation and impaired systemic blood flow. Right ventricular performance and the patency and direction of the ductus arteriosus may play a crucial role in postductal organ perfusion. Physiological stabilization may be complex and variable over time. The utilization of targeted neonatal echocardiography to guide treatment decisions may improve the ability to provide therapy tailored to the specific disease pathophysiology and monitor serially as conditions change. An enhanced approach to physiological stabilization may reduce the risk of unexpected decompensation and allow for thoughtful, controlled endovascular embolization in appropriate candidates.

scholarly journals Neurocognitive improvements following endovascular repair of vein of Galen malformation in a child

2015 ◽  
Vol 15 (2) ◽  
pp. 197-202 ◽  
Author(s):  
Robyn A. Howarth ◽  
Andrew Reisner ◽  
Joshua J. Chern ◽  
Laura L. Hayes ◽  
Thomas G. Burns ◽  
...  
Keyword(s):  
Successful Treatment ◽  
Endovascular Repair ◽  
Endovascular Embolization ◽  
Initial Presentation ◽  
Cognitive Deterioration ◽  
Vein Of Galen ◽  
Neurocognitive Deficits ◽  
Vein Of Galen Malformation ◽  
Neurocognitive Profile

Cognitive regression is a well-described presentation of vein of Galen aneurysmal malformations (VGAMs) in childhood. However, it remains unclear whether successful treatment of the malformation can reverse cognitive regression. Here, the authors present the case of a 5-year-old girl with a VGAM that was treated with staged endovascular embolization procedures. Comprehensive neurocognitive assessments were completed before intervention and approximately 6 years after initial presentation. There were significant age-matched improvements in this child's neurocognitive profile over this period. The authors believe that timely and successful treatment of VGAM in children may not only stabilize the associated cognitive deterioration but, in some cases, may ameliorate these deficits. Details of this case and a discussion of neurocognitive deficits related to VGAM are presented.

Rare basal vein fistula with dilated vein of Galen

2012 ◽  
Vol 9 (3) ◽  
pp. 331-334 ◽  
Author(s):  
Srinivasan Paramasivam ◽  
Johanna T. Fifi ◽  
Rafael A. Ortiz ◽  
Yasunari Niimi ◽  
Alejandro Berenstein
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Male Infant ◽  
Normal Pregnancy ◽  
Endovascular Embolization ◽  
Vein Of Galen ◽  
Management Options ◽  
Excellent Outcome ◽  
Pregnancy And Delivery ◽  
Basal Vein Of Rosenthal

The authors present a rare case of arteriovenous fistula (AVF) of the basal vein of Rosenthal draining into a dilated vein of Galen managed by transarterial endovascular embolization. A male infant born at full term following a normal pregnancy and delivery with congestive heart failure, on investigation with MR imaging and MR angiography was found to have a basal vein of Rosenthal fistula with a dilated vein of Galen. His congestive heart failure was treated medically, and the AVF was managed electively at 10 months of age with successful transarterial endovascular embolization. The authors discuss the embryological aspects related to the pathological entity and the various clinical presentations, investigations, and management options. Management is primarily endovascular embolization; microsurgery is performed for a few selected cases, and radiosurgery has a limited role in older patients. Endovascular embolization is a safe and effective way to manage this malformation, with an excellent outcome if the AVF is eliminated by proper embolization at the fistulous point.

Vein of Galen Malformation

2018 ◽  
Author(s):  
Elizabeth C. Eastburn ◽  
Mary Landrigan-Ossar
Keyword(s):  
Vascular Lesion ◽  
Endovascular Embolization ◽  
Neurological Dysfunction ◽  
Vein Of Galen ◽  
Vein Of Galen Malformation ◽  
Initial Symptoms ◽  
History Of ◽  
Flow Through ◽  
Intracranial Vascular Malformation ◽  
Selection Of

Vein of Galen malformation (VGM) is a high-flow intracranial vascular malformation, presenting in utero or after birth with a range of initial symptoms. The natural history of untreated VGM is grave, with progressive permanent neurological dysfunction, developmental delay, seizures, intracranial hemorrhage, and death. Presentation varies with age, with more severe manifestations resulting in earlier presentation and poorer outcome. The mainstay of treatment is medical stabilization followed by endovascular embolization. The goal is to reduce flow through the malformation such that normal development can proceed without neurological deficit. The past 20 years have seen great advances both in the technical treatment of the vascular lesion and in the overall prognosis of patients treated for this condition. Key to a good outcome is appropriate selection of patients and treatment by physicians familiar with this pathophysiology.

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