scholarly journals Carotid artery intima-media thickness measurement in children with normal and increased body mass index: a comparison of three techniques

2018 ◽  
Vol 48 (8) ◽  
pp. 1073-1079 ◽  
Author(s):  
Ramy El Jalbout ◽  
Guy Cloutier ◽  
Marie-Hélène Roy Cardinal ◽  
Mélanie Henderson ◽  
Chantale Lapierre ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Carotid Artery ◽  
Body Mass ◽  
Intima Media Thickness ◽  
Thickness Measurement ◽  
Media Thickness

scholarly journals Correction to: Carotid artery intima-media thickness measurement in children with normal and increased body mass index: a comparison of three techniques

2018 ◽  
Vol 48 (8) ◽  
pp. 1080-1080
Author(s):  
Ramy El Jalbout ◽  
Guy Cloutier ◽  
Marie-Hélène Roy Cardinal ◽  
Mélanie Henderson ◽  
Chantale Lapierre ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Carotid Artery ◽  
Body Mass ◽  
Intima Media Thickness ◽  
Thickness Measurement ◽  
Media Thickness

scholarly journals P1836 Common carotid artery intima-media thickness correlates with the epicardial fat thickness in patients with ischemic stroke

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
D Serova ◽  
V Serov ◽  
A Shutov ◽  
S Serova ◽  
A Kovalenko ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Ischemic Stroke ◽  
Carotid Artery ◽  
Body Mass ◽  
Common Carotid Artery ◽  
Intima Media Thickness ◽  
Epicardial Fat ◽  
Epicardial Fat Thickness ◽  
Media Thickness ◽  
Fat Thickness

Abstract The relationship between epicardial fat thickness and coronary atherosclerosis is well known, but the value of the increased epicardial fat thickness in cerebrovascular diseases is still unclear. Purpose The aim of this study was to determine the relationship between common carotid artery intima–media thickness (CCA-IMT), the resistance index (RI) in the vertebral and carotid arteries and epicardial fat thickness (EFT) in patients with ischemic stroke. Methods 98 patients with ischemic stroke (31 females and 67 males, mean age was 68.2 ± 12.1 years) were studied. All patients had arterial hypertension (AH). Most of them (96.9%) had grade 3 hypertension according to ESH/ESC Guidelines for the management of arterial hypertension, 2018. Forty-two (43.1%) patients had coronary artery disease and 35 (35.4%) - atrial fibrillation (AF). The exclusion criteria was the presence of chronic obstructive pulmonary disease or other diseases associated with pulmonary hypertension. Patients were categorized according to National Institutes of Health Stroke Scale (NIHSS) severity in mild NIHSS (≤8) - 54 (55.1%) patients, moderate NIHSS (9–15) - 23 (23.5%) patients, and severe stroke NIHSS (≥16) - 21 (21.4%) patients. Median NIHSS score was 11.2 ± 1.7. All patients underwent a transthoracic echocardiography and a carotid ultrasound examination. Results The common carotid artery intima–media thickness correlated with EFT (r =0.78, p < 0.001), the body mass index (r = 0.7, p < 0.001) and systolic blood pressure (r = 0.25, p = 0.045). The resistance index in the vertebral and carotid arteries correlated only with EFT (r = 0.7, p < 0.001 and r = 0.78, p < 0.001, respectively) and body mass index (r = 0.58, p < 0.001 and r = 0.68, p < 0.001, respectively). A multiple regression analysis in which the CCA-IMT was a dependent variable and age, body mass index, systolic blood pressure, blood cholesterol level and epicardial fat thickness were independent variables, showed that CCA-IMT was independently correlated with blood cholesterol level (β=0.714, р<0.001) and EFT (β =0.255, р=0.002) in patients with ischemic stroke. Conclusions The common carotid artery intima–media thickness and parameters of the arterial stiffness of the extracranial vessels of the head are associated with the epicardial fat thickness and blood cholesterol level in patients with ischemic stroke. The common carotid artery intima–media thickness does not depend on age, gender, body mass index, systolic and diastolic blood pressure in patients with ischemic stroke.

scholarly journals Sex modifies the association between body mass index and carotid artery intima media thickness in the multi-ethnic Singapore population

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
R Dalan ◽  
T Mina ◽  
N A Nur Azizah ◽  
T Tong ◽  
M Loh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Cardiovascular Risk Factors ◽  
Body Mass ◽  
Intima Media Thickness ◽  
Cvd Risk ◽  
Media Thickness ◽  
Healthy Participants

Abstract Background and aims Globally cardiovascular disease (CVD) risk is higher in men than in women in the younger age group but the risk is attenuated in later life with an unexpected higher risk in women in some populations. A better understanding of sex differences in CVD is needed. Carotid artery intima-media thickness (CIMT) has been proposed for CVD risk assessment in individuals at intermediate risk. We study the gender interactions in the associations of the traditional cardiovascular risk factors with CIMT. Methods We performed carotid ultrasonography in the large population health study-HELIOS conducted in Singapore. Measurements were performed as per Mannheim consensus, at the far wall of bilateral common carotid artery at 8 sites in each participant. We report the average of all measurements (avgCIMT) and maximum value (maxCIMT). We analysed 2061 healthy participants recruited between 2018–2020. Inclusion criteria for this analysis: non-smokers, not known to have diabetes, hypertension, hyperlipidemia or ischemic heart disease. Individuals with systolic blood pressure >160 mm Hg or fasting glucose >7.0 mmol/L on recruitment were excluded. Multivariable linear regression analysis was performed to examine the association between CIMT and cardiovascular risk factors in the healthy population adjusting for age, sex and ethnicity. All analysis was performed using Stata version 16.0. Results After exclusion, 1407 healthy participants were included in the analysis. Median (IQR) avgCIMT: 0.56 (0.50, 0.65) in men; 0.54 (0.50, 0.58) in women. Median (IQR) maxCIMT: 0.64 (0.57, 0.76) in men; 0.61 (0.54, 0.70) in women. The avgCIMT and the maxCIMT were higher in males when compared to women and all traditional cardiovascular risk factors associated with CIMT after adjustment for age, sex and ethnicity (P<0.05) (Table 1). Interaction tests in multivariable model adjusted for age, ethnicity, pulse pressure, non HDL-C and HbA1c showed a significant interaction between sex and body mass index (BMI) with predicted effects on avgCIMT and maxCIMT being relatively higher in males at the same BMI when compared to females (P-interaction <0.01) (Figure 1). Conclusion Sex modifies the relationship between BMI and CIMT in Singapore's multi-ethnic population. Understanding the intermediary mechanisms involved will help in developing personalized preventive strategies. FUNDunding Acknowledgement Type of funding sources: None. Figure 1

scholarly journals Vascular diameter and intima-media thickness to diameter ratio values of the carotid artery in 642 healthy children

2020 ◽  
Author(s):  
Luisa Semmler ◽  
Heidi Weberruß ◽  
Lisa Baumgartner ◽  
Raphael Pirzer ◽  
Renate Oberhoffer-Fritz
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Cardiovascular Risk ◽  
Carotid Artery ◽  
Tensile Stress ◽  
Body Mass ◽  
Intima Media Thickness ◽  
Diameter Ratio ◽  
Healthy Children ◽  
Media Thickness

Abstract In children, arterial alterations occur with increased intima-media thickness as well as vascular diameter enlargement. Both conditions correlate with higher cardiovascular risk in adults, and both the array and proportion of these alterations are important hemodynamic parameters. In terms of functional adaptation processes, they influence several arterial wall properties as for example the shear and tensile stress of the vessel. There are no reference values for the vascular diameter and intima-media thickness/diameter ratio of the carotid artery in children. Therefore, this study aimed to assess vascular diameter, intima-media thickness/diameter ratio and related tensile stress values in children and to further investigate the influence of sex, age, body mass index, and blood pressure. The parameters were measured with high-resolution semi-automated ultrasound. Sex- and age-dependent values were calculated with the LMS method for a cross-sectional sample of 642 healthy, non-obese children aged 8–17 years. The mean vascular diameter was 5.45 ± 0.46 mm; the median intima-media thickness/diameter ratio was 0.085 (0.079–0.092); the median tensile stress was 105.4 (95.2–116.4) kPa. The vascular diameter and the tensile stress were higher, and the intima-media thickness/diameter ratio was lower in boys than in girls. In comparison to the normal weight study population the excludedobese children had a significantly higher diameter, a lower intima-media thickness/diameter ratio, and a higher tensile stress. In multiple regression analyses of diameter, intima-media thickness/diameter ratio, and tensile stress, all parameters were influenced by sex and body mass index. Furthermore, systolic and diastolic blood pressure significantly influenced the vascular diameter, and systolic blood pressure significantly influenced the intima-media thickness/diameter ratio. Conclusion: This study is the first to report values for the diameter, the intima-media thickness/diameter ratio of the carotid artery, and the related tensile stress allowing a more differentiated view of cardiovascular adaptations as it combines structural and functional vascular parameters. What is known:• Intima-media thickness and vascular diameter are related to a higher cardiovascular risk in adults• The intima-media thickness/diameter ratio gives information about hemodynamic and functional vessel adaptationWhat is new:• Values for vascular diameter, intima-media thickness/diameter ratio, and tensile stress of the carotid artery in children are presented in this study• Intima-media thickness as a surrogate marker for arterial health in children should be complemented by intima-media thickness/diameter ratio measurement

Intima-media thickness measurement of the carotid artery in patients with primary hyperparathyroidism

2015 ◽  
Author(s):  
Dilek Tuzun ◽  
Ayten Oguz ◽  
Murat Sahin ◽  
Safa Ersen Ganidagli ◽  
Didem Atay ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Primary Hyperparathyroidism ◽  
Intima Media Thickness ◽  
Thickness Measurement ◽  
Media Thickness

Abstract P301: Association of Toenail Cadmium Levels with Measures of Sub-Clinical Atherosclerosis: The Coronary Artery Risk Development in Young Adults (CARDIA) Trace Element Study

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Pengcheng Xun ◽  
Kiang Liu ◽  
Steve Morris ◽  
Martha Daviglus ◽  
Catherine Loria ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Coronary Artery ◽  
Body Mass ◽  
Smoking Status ◽  
Experimental Studies ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Omega 3 ◽  
Media Thickness ◽  
Cd Exposure

Background: Experimental studies have suggested that cadmium (Cd) exposure is a potential risk factor for early atherosclerosis and cardiovascular diseases as it can disrupt integrity of the endothelial cell layer. However, longitudinal data in humans relating Cd levels to sub-clinical atherosclerosis are lacking. Methods: 2589 participants from the CARDIA Study, aged 20-32 years in 1987 (baseline) with up to 18 years of follow-up were included in the analyses to examine prospectively the associations of toenail Cd concentrations with carotid intima-media thickness (CIMT) and coronary artery calcium score (CAC score). Toenail clippings were collected in 1987 and Cd was assessed by instrumental neutron-activation analysis. Common (c), bulb (b), and internal (i) CIMTs were measured in 2005 and CAC score in 2000 and 2005. CAC presence (score, >0 Agatston units) and CAC progression (incident CAC in 2005 or increase in CAC score by ≥10 Agatston units) were defined based on CAC score. General linear regression or logistic regression was used as appropriate. Results: Median Cd levels were 0.003, 0.006, 0.012 and 0.039 μ g/g from 1 st - 4 th quartile. We observed a positive linear relation of Cd levels with cCIMT, but not bCIMT and iCIMT ( Table 1 ). Null associations between Cd levels and CAC progression [Q 4 vs . Q 1 : OR=1.11 (95% CI: 0.73, 1.68); P trend =0.14] or presence of CAC [Q 4 vs . Q 1 : OR=1.05 (0.73, 1.53); P trend =0.56] were documented. Conclusions: In this young adult cohort, toenail Cd levels were positively associated with cCIMT, but not bCIMT, iCIMT and CAC score. Further studies are needed to determine whether there is an atherosclerotic mechanism linking Cd exposure to the risk of cardiovascular disease. Table 1 Multivariable-adjusted carotid intima-media thickness (mm) by toenail cadmium levels No. of participants Quartile of toenail cadmium levels P trend Q1 Q2 Q3 Q4 cCIMT 2587 0.781 (0.773-0.790) 0.784 (0.776-0.793) 0.789 (0.781-0.798) 0.791 (0.781-0.798) 0.03 bCIMT 2527 1.010 (0.990-0.1.031) 1.002 (0.982-1.022) 0.981 (0.962-1.001) 1.001 (0.980-1.022) 0.17 iCIMT 2436 0.787 (0.772-0.802) 0.790 (0.776-0.804) 0.784 (0.770-0.798) 0.778 (0.763-0.793) 0.86 Data are geometric means (95%CIs) adjusted for age, gender, race, study center, body mass index, physical activity, education, smoking status, alcohol consumption, systolic blood pressure, LDL/HDL, HOMA, body mass index, long-chain omega-3 polyunsaturated fatty acids intake with toenail zinc, chromium, lead and mass weight. cCIMT : common carotid intima-media thickness; bCIMT : bulb carotid intima-media thickness; iCIMT : internal carotid intima-media thickness.

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