Molecular cloning, characterization, and quantification of squirrel monkey ( Saimiri sciureus ) Th1 and Th2 cytokines

2002 ◽  
Vol 54 (1) ◽  
pp. 20-29 ◽  
Author(s):  
Jean-Michel Heraud, Anne Lavergne, Mirdad Kazan
2011 ◽  
Vol 39 (2) ◽  
pp. 170-182
Author(s):  
S. Suzuki ◽  
S. Konnai ◽  
T. Okagawa ◽  
N. W. Githaka ◽  
E. Kariuki ◽  
...  

Author(s):  
Myungwon Choi ◽  
Indal Park ◽  
Jaehyun Ju ◽  
Kun-Young Park ◽  
Kwang Hyuk Kim

1995 ◽  
Vol 54 (7) ◽  
pp. 560-565 ◽  
Author(s):  
J F Schlaak ◽  
A Schwarting ◽  
P Knolle ◽  
K H Meyer zum Buschenfelde ◽  
W Mayet

Author(s):  
Damián Kovalovsky ◽  
Marcelo Páez Pereda ◽  
Joachim Sauer ◽  
Carolina Perez Castro ◽  
Victor E. Nahmod ◽  
...  

2002 ◽  
Vol 81 (5) ◽  
pp. 303-307 ◽  
Author(s):  
E. Gemmell ◽  
C.L. Carter ◽  
D.A. Grieco ◽  
P.B. Sugerman ◽  
G.J. Seymour

Animals ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 245 ◽  
Author(s):  
Leying Zhang ◽  
Zimo Zhao ◽  
Hao Mi ◽  
Baoliang Liu ◽  
Bin Wang ◽  
...  

There is an immune tolerance in maternal immune system during pregnancy, and thymus is a main organ of the immune system. Helper T (Th)1 and Th2 cytokines are involved in the regulation of immune system, but the modulation of Th cytokines in the thymus during early pregnancy is unclear in ewes. Thymuses were collected on day 16 of the estrous cycle, and on days 13, 16, and 25 of pregnancy in ewes. qRT-PCR, Western blot, and immunohistochemistry were used to analyze the expression of Th1 and Th2 cytokines in the thymuses. There was a peak in the expression of interferon-gamma (IFN-γ) on day 16 of pregnancy, an upregulation of tumor necrosis factor beta (TNF-β), and a sustained expression of interleukin-2 (IL-2) and IL-4. Furthermore, there was a peak in the expression of IL-6 on day 13 of pregnancy, no expression of IL-6 on day 16 of the estrous cycle and day 25 of pregnancy, and an upregulation of IL-5 and IL-10 in the thymuses during early pregnancy. The immunohistochemistry results revealed that the IFN-γ and IL-6 proteins were limited to the stromal cells, capillaries, and thymic corpuscles. In conclusion, early pregnancy influenced the production of Th1 and Th2 cytokines of maternal thymus in sheep.


2009 ◽  
Vol 123 (2) ◽  
pp. S255-S255
Author(s):  
D. Asaka ◽  
T. Nakajima ◽  
T. Ohno ◽  
Y. Matsuwaki ◽  
H. Moriyama ◽  
...  

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