T2 star relaxation times for assessment of articular cartilage at 3 T: a feasibility study

2011 ◽  
Vol 41 (3) ◽  
pp. 287-292 ◽  
Author(s):  
Tallal Charles Mamisch ◽  
Timothy Hughes ◽  
Timothy J. Mosher ◽  
Christoph Mueller ◽  
Siegfried Trattnig ◽  
...  
2014 ◽  
Vol 905 ◽  
pp. 498-501
Author(s):  
Bo Li Su ◽  
Wei Zhi Qi ◽  
Xue Liang Xu ◽  
L. Huang ◽  
X.C. Zhong ◽  
...  

We present a pilot study for the first time that microwave-induced thermoacoustic tomography (TAT) has the potential to detect osteoarthritis (OA) in the finger jointsin vitro. In this study, we use rabbit hind feet to imitate humans finger joints, one rabbits hind feet was examined carefully by a TAT scanner, and the two-dimensional (2D) thermoacoustic images were reconstructed by the delay-and-sum algorithm. The difference of absorption coefficient of bone and articular cartilage has been displayed clearly in the reconstruction images.


2016 ◽  
Vol 89 (1064) ◽  
pp. 20151075 ◽  
Author(s):  
Cyrus Behzadi ◽  
Goetz H Welsch ◽  
Azien Laqmani ◽  
Frank O Henes ◽  
Michael G Kaul ◽  
...  

2012 ◽  
Vol 134 (2) ◽  
Author(s):  
M. Kazemi ◽  
L. P. Li ◽  
M. D. Buschmann ◽  
P. Savard

Partial meniscectomy is believed to change the biomechanics of the knee joint through alterations in the contact of articular cartilages and menisci. Although fluid pressure plays an important role in the load support mechanism of the knee, the fluid pressurization in the cartilages and menisci has been ignored in the finite element studies of the mechanics of meniscectomy. In the present study, a 3D fibril-reinforced poromechanical model of the knee joint was used to explore the fluid flow dependent changes in articular cartilage following partial medial and lateral meniscectomies. Six partial longitudinal meniscectomies were considered under relaxation, simple creep, and combined creep loading conditions. In comparison to the intact knee, partial meniscectomy not only caused a substantial increase in the maximum fluid pressure but also shifted the location of this pressure in the femoral cartilage. Furthermore, these changes were positively correlated to the size of meniscal resection. While in the intact joint, the location of the maximum fluid pressure was dependent on the loading conditions, in the meniscectomized joint the location was predominantly determined by the site of meniscal resection. The partial meniscectomy also reduced the rate of the pressure dissipation, resulting in even larger difference between creep and relaxation times as compared to the case of the intact knee. The knee joint became stiffer after meniscectomy because of higher fluid pressure at knee compression followed by slower pressure dissipation. The present study indicated the role of fluid pressurization in the altered mechanics of meniscectomized knees.


2012 ◽  
Vol 27 (4) ◽  
pp. 403-408 ◽  
Author(s):  
Richard B. Souza ◽  
Charles Fang ◽  
Anthony Luke ◽  
Samuel Wu ◽  
Xiaojuan Li ◽  
...  

2011 ◽  
Vol 133 (10) ◽  
Author(s):  
J. W. Ruberti ◽  
J. B. Sokoloff

Articular cartilage is comprised of macromolecules, proteoglycans, with (charged) chondroitin sulfate side-chains attached to them. The proteoglycans are attached to longer hyaluronic acid chains, trapped within a network of type II collagen fibrils. As a consequence of their relatively long persistence lengths, the number of persistence lengths along the chondroitin sulfate and proteoglycan chains is relatively small, and consequently, the retraction times for these side chains are also quite short. We argue that, as a consequence of this, they will not significantly inhibit the reptation of the hyaluronic acid chains. Scaling arguments applied to this model allow us to show that the shortest of the mechanical relaxation times of cartilage, that have been determined by Fyhrie and Barone to be due to reptation of the hyaluronic acid polymers, should have a dependence on the load, i.e., force per unit interface area P, carried by the cartilage, proportional to P3/2.


2012 ◽  
Vol 40 (9) ◽  
pp. 2134-2141 ◽  
Author(s):  
Karupppasamy Subburaj ◽  
Deepak Kumar ◽  
Richard B. Souza ◽  
Hamza Alizai ◽  
Xiaojuan Li ◽  
...  

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