scholarly journals A Primer on a Hepatocellular Carcinoma Bioresource Bank Using the Cancer Genome Atlas Guidelines: Practical Issues and Pitfalls

2011 ◽  
Vol 35 (8) ◽  
pp. 1732-1737 ◽  
Author(s):  
N. Thao T. Nguyen ◽  
Ron T. Cotton ◽  
Theresa R. Harring ◽  
Jacfranz J. Guiteau ◽  
Marie-Claude Gingras ◽  
...  
Bioengineered ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 759-768
Author(s):  
Jun Liu ◽  
Guili Sun ◽  
Shangling Pan ◽  
Mengbin Qin ◽  
Rong Ouyang ◽  
...  

2020 ◽  
Vol 10 (8) ◽  
pp. 1189-1196
Author(s):  
Kaikai Ren ◽  
Jiakang Ma ◽  
Bo Zhou ◽  
Xiaoyan Lin ◽  
Mingyu Hou ◽  
...  

Hepatocellular carcinoma (HCC) is a malignancy originating from hepatocytes with a high rate of distant metastasis and recurrence. HCC prognosis remains poorly understood, although its diagnosis and treatment have improved globally. Therefore, it is necessary to identify reliable predictive and prognostic indicators of HCC. HCC gene expression profiles and corresponding clinical data were downloaded from The Cancer Genome Atlas. Seven lncRNAs (C10orf91, AC011352.3, AC015722.2, AC006372.1, PICSAR, AC110285.3, and AP001972.4) associated with immune and clinicopathological features were identified as biomarker candidates for HCC prognosis based on single-sample gene set enrichment analysis, the ESTIMATE algorithm, and Cox PHR analyses. Altogether, the findings revealed that the seven immune-related lncRNAs may provide a reference for improving HCC prognosis.


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