The role of Pseudomonas aeruginosa isolates
among the pathogens of surgical infection in
purulent-septic surgery department for 2018
is determined. Investigated the antibiotic
resistance of Pseudomonas aeruginosa hospital
strains and the most effective antibiotics
were investigated. Poly resistant in wound
material were almost half of the cultures of
Pseudomonas aeruginosa (19 strains, 45,2%).
Carbapenem resistant Pseudomonas aeruginosa
was found to be 47,1%. Of the aminoglycoside
group antibiotics, Tobramycin (82,1%) showed
the best sensitivity, Amikacin was sensitive in
half of the microorganisms tested (55,0%). The
sensitivity of cephalosporins ranged from 23,1%
(Cefoperazone) to 40,5% (Ceftazidime). Even
the use of the Sulbactam protective molecule did
not improve the situation: 37,5% (Cefoperazone/
Sulbactam). For fluoroquinolones (Ciprofloxacin)
sensitive third part of bacteria only. Piperacillin
with Tazobactam, Fosfomycin, and Colistin E
showed a high anti-pseudomonad efficacy. The use
of anti-diarrhea bacteriophage was ineffective.
Keywords: hospital strains, antibiotic
resistance, Pseudomonas aeruginosa.