Transmission dynamics for vector-borne diseases in a patchy environment

2013 ◽  
Vol 69 (1) ◽  
pp. 113-146 ◽  
Author(s):  
Yanyu Xiao ◽  
Xingfu Zou
Keyword(s):  
Transmission Dynamics ◽  
Patchy Environment ◽  
Vector Borne Diseases ◽  
Vector Borne

scholarly journals Modeling the propagation of the Dengue, Zika and Chikungunya virus in the city of Bello using Agent-Based Modeling and Simulation

2021 ◽  
Author(s):  
Rafael Mateus Carrion ◽  
Susana Alvarez Zuluaga ◽  
Mariajose Franco Orozco ◽  
Paula Alejandra Escudero Marín
Keyword(s):  
Computational Cost ◽  
Simulation Models ◽  
Transmission Dynamics ◽  
Agent Based ◽  
Vector Borne Diseases ◽  
Ode Models ◽  
Vector Borne ◽  
Future Work ◽  
The City ◽  
High Computational Cost

Agent-Based Models (ABM) have become a very useful tool to simulate the propagation of infectious diseases. To enhance the scope of these simulation models, some authors have combined ABMs with ODE models which are called Hybrid ABMs, and allows the simulation of models that demand a very high computational cost. In the present project, the main approach is to develop hybrid ABMs to understand the transmission dynamics of vector-borne diseases such as Dengue, Zika, and Chikungunya considering some geospatial characteristics of the city of Bello, Colombia. Some assumptions were considered to develop the computational model to understand and verify if the transmission dynamics were happening according to their theoretical behavior. The results obtained were satisfactory, and for future work, the idea is to integrate more components and make the model more realistic.

scholarly journals Scoping review on vector-borne diseases in urban areas: transmission dynamics, vectorial capacity and co-infection

2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Marcus Eder ◽  
Fanny Cortes ◽  
Noêmia Teixeira de Siqueira Filha ◽  
Giovanny Vinícius Araújo de França ◽  
Stéphanie Degroote ◽  
...  
Keyword(s):  
Scoping Review ◽  
Urban Areas ◽  
Vectorial Capacity ◽  
Transmission Dynamics ◽  
Vector Borne Diseases ◽  
Vector Borne

scholarly journals Analyzing the Effects of Temperature and Human Movement on Malaria Disease Transmission Dynamics

2020 ◽  
Author(s):  
Ganga Ram Phaijoo
Keyword(s):  
Disease Transmission ◽  
Human Movement ◽  
Transmission Dynamics ◽  
Vector Borne Diseases ◽  
Movement Rates ◽  
Anopheles Mosquitoes ◽  
Vector Borne ◽  
Temperature Levels ◽  
Global And Local ◽  
The Impact

Abstract Background: Malaria disease is transmitted by the bite of Anopheles mosquitoes. Plasmodium parasites are responsible for the disease. Due to human movement from one place to the other, vector borne diseases like malaria are spreading rapidly throughout the world. They have become major causes of morbidity and mortality worldwide. Changing temperature levels has significant impact on the life cycle, biting behavior and death rates of the mosquitoes which can transmit the disease.Methods: A multi patch SEIRS - SEI deterministic compartmental model for malaria disease is developed to study the disease transmission dynamics. The impact of temperature and human movement in transmission dynamics is investigated. Both global and local basic reproduction numbers are computed for two patches in two patch setting.Results: Disease free equilibrium is locally stable when the basic reproduction number is less than unity and unstable when the number is greater than unity. Numerical results show that the prevalence of the disease changes with the change in human movement rates between the patches; temperature affects the transmission dynamics of malaria disease.Conclusion: The burden of malaria disease can be reduced by managing the host movement between low and high disease prevalent patches. The optimal temperature for malaria disease transmission is 25 °C.

The Spread of Mosquito Borne Disease – Is Climate Change Beginning to Bite?

2019 ◽  
Vol 30 (5) ◽  
pp. 192-194
Author(s):  
John (Luke) Lucas
Keyword(s):  
Climate Change ◽  
Vector Borne Diseases ◽  
Vector Borne

The author considers the threat to vector-borne diseases in the light of climate change.

The Scientific Basis for the Prevention of Zooanthroponoze Vector-Borne Diseases Spread by Parasitic Arthropods of the Center of the East European Plain

2020 ◽  
Vol 14 (1) ◽  
pp. 81-88
Author(s):  
Fedor I. Vasilevich ◽  
Anna M. Nikanorova
Keyword(s):  
Mathematical Models ◽  
Culex Pipiens ◽  
Preventive Measures ◽  
Mosquito Species ◽  
Natural Habitat ◽  
Piperonyl Butoxide ◽  
East European Plain ◽  
Vector Borne Diseases ◽  
Vector Borne ◽  
Kaluga Region

The purpose of the research is development of preventive measures against zooanthroponoze vector-borne diseases spread by parasitic arthropods in the Kaluga Region. Materials and methods. The subject of the research was Ixodidae, mosquitoes, and small mammals inhabiting the Kaluga Region. The census of parasitic arthropods was carried out on the territory of all districts of the Kaluga Region and the city of Kaluga. Open natural habitat and human settlements were investigated. Weather conditions from 2013 to 2018 were also taken into account. For the purposes of the study, we used standard methods for capturing and counting arthropods and mouse-like rodents. In order to obtain mathematical models of small mammal populations, a full factorial experiment was conducted using the collected statistical data. In-process testing of the drug based on s-fenvalerate and piperonyl butoxide were carried out under the conditions of the agricultural collective farm “Niva” of the Kozelsky District, the Kaluga Region, and LLC “Angus Center of Genetics” of the Babyninsky District, the Kaluga Region. Results and discussion. In the Kaluga Region, two species of ixodic ticks are found, namely, Ixodes ricinus and Dermacentor reticulatus, which have two activity peaks. Mosquito may have 3-4 generations in a year in the Kaluga region. The most common mosquito species in the Kaluga Region are Aedes communis, Ae. (Och.) togoi and Ae. (Och.) diantaeus, Culex pipiens Culex Linnaeus, 1758 (Diptera, Culicidae) (Culex pipiens): Cx. pipiens f. pipiens L. (non-autogenic form) and Cx. p. f. molestus Fors. (autogenic form), which interbreed, and reproductively isolated in the Region. The developed mathematical models make it possible to quantify the risks of outbreaks of zooanthroponoze vector-borne diseases without the cost of field research, and allow for rational, timely and effective preventive measures. Medications based on s-fenvalerate and piperonyl butoxide and based on cyfluthrin showed high insecto-acaricidal efficacy and safety.

Current Challenges in the Development of Vaccines and Drugs Against Emerging Vector-borne Diseases

2019 ◽  
Vol 26 (16) ◽  
pp. 2974-2986 ◽  
Author(s):  
Kwang-sun Kim
Keyword(s):  
New Host ◽  
In Vivo Models ◽  
Vector Borne Diseases ◽  
Novel Drugs ◽  
Huge Impact ◽  
Tick Borne Disease ◽  
Vector Borne ◽  
Living Organisms

Vectors are living organisms that transmit infectious diseases from an infected animal to humans or another animal. Biological vectors such as mosquitoes, ticks, and sand flies carry pathogens that multiply within their bodies prior to delivery to a new host. The increased prevalence of Vector-Borne Diseases (VBDs) such as Aedes-borne dengue, Chikungunya (CHIKV), Zika (ZIKV), malaria, Tick-Borne Disease (TBD), and scrub typhus has a huge impact on the health of both humans and livestock worldwide. In particular, zoonotic diseases transmitted by mosquitoes and ticks place a considerable burden on public health. Vaccines, drugs, and vector control methods have been developed to prevent and treat VBDs and have prevented millions of deaths. However, development of such strategies is falling behind the rapid emergence of VBDs. Therefore, a comprehensive approach to fighting VBDs must be considered immediately. In this review, I focus on the challenges posed by emerging outbreaks of VBDs and discuss available drugs and vaccines designed to overcome this burden. Research into promising drugs needs to be upgraded and fast-tracked, and novel drugs or vaccines being tested in in vitro and in vivo models need to be moved into human clinical trials. Active preventive tactics, as well as new and upgraded diagnostics, surveillance, treatments, and vaccination strategies, need to be monitored constantly if we are to manage VBDs of medical importance.

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