Individualized coronary calcium scoring at any tube voltage using a kV-independent reconstruction algorithm

2020 ◽  
Vol 30 (11) ◽  
pp. 5834-5840
Author(s):  
Vincenzo Vingiani ◽  
Andres F. Abadia ◽  
U. Joseph Schoepf ◽  
Andreas M. Fischer ◽  
Akos Varga-Szemes ◽  
...  
Keyword(s):  
Reconstruction Algorithm ◽  
Coronary Calcium ◽  
Calcium Scoring ◽  
Tube Voltage ◽  
Coronary Calcium Scoring

scholarly journals PROSPECTIVE EVALUATION OF LOW-DOSE CORONARY CALCIUM SCORING WITH REDUCED TUBE VOLTAGE

2017 ◽  
Vol 69 (11) ◽  
pp. 1560
Author(s):  
Christoph Gräni ◽  
Jan Vontobel ◽  
Dominik Benz ◽  
Sara Bacanovic ◽  
Beatrice Hirt Moch ◽  
...  
Keyword(s):  
Low Dose ◽  
Coronary Calcium ◽  
Calcium Scoring ◽  
Prospective Evaluation ◽  
Tube Voltage ◽  
Coronary Calcium Scoring

Value of Coronary Calcium Scoring in Symptomatic and Asymptomatic Coronary Artery Disease Patients

2020 ◽  
Vol 16 ◽  
Author(s):  
Hala T. Salem ◽  
Eman A.S. Sabek
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Sensitivity And Specificity ◽  
High Sensitivity ◽  
Coronary Calcium ◽  
Risk Estimate ◽  
Calcium Scoring ◽  
Coronary Calcium Scoring ◽  
Framingham Risk ◽  
Artery Disease

Aim and Objective: To estimate the relationship between Coronary Calcium Scoring (CCS)and presence of different degrees of obstructive coronary artery disease (CAD) to avoid unnecessary examinations and hence unnecessary radiation exposure and contrast injection. Background: Coronary Calcium Scoring (CCS) is a test uses x-ray equipment to produce pictures of the coronary arteries to determine the degree of its narrowing by the build-up of calcified plaques. Despite the lack of definitive data linking ionizing radiation with cancer, the American Heart Association supports widely that practitioners of Computed tomography Coronary Angiography (CTCA) should keep “patient radiation doses as low as reasonably achievable but consistent with obtaining the desired medical information”. Methods: Data obtained from 275 CTCA examinations were reviewed. Radiation effective doses were estimated for both CCS and CTCA, measures to keep it as low as possible were presented, CCS and Framingham risk estimate were compared to the final results of CTCA to detect sensitivity and specificity of each one in detecting obstructive lesions. Results: CCS is a strong discriminator for obstructive CAD and can with high sensitivity and specificity and correlates well with the degree of obstruction even more than Framingham risk estimate which has high sensitivity and low specificity. Conclusion: CCS helps reducing the effective radiation dose if properly evaluated to skip unnecessary CTCA if obstructive lesions was unlikely, and as a test does not use contrast material, harmful effect on the kidney will be avoided as most of coronary atherosclerotic patients have renal problems.

scholarly journals Radiation dose values for various coronary calcium scoring protocols in dual-source CT

2008 ◽  
Vol 25 (4) ◽  
pp. 443-451 ◽  
Author(s):  
Paul Stolzmann ◽  
Sebastian Leschka ◽  
Thomas Betschart ◽  
Lotus Desbiolles ◽  
Thomas G. Flohr ◽  
...  
Keyword(s):  
Radiation Dose ◽  
Coronary Calcium ◽  
Dual Source Ct ◽  
Calcium Scoring ◽  
Coronary Calcium Scoring ◽  
Dual Source

Abstract 2759: Elevated Coronary Calcium Scores Measured by Multi-Slice Computed Tomography are Associated with Low Response to Clopidogrel in Patients with Stable Angina pectoris

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Christof Burgstahler ◽  
Tobias Geisler ◽  
Stephan Lindemann ◽  
Anja Reimann ◽  
Harald Brodoefel ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Stent Placement ◽  
Calcium Score ◽  
Significant Negative Correlation ◽  
Coronary Calcium ◽  
Plaque Burden ◽  
Agatston Score ◽  
Calcium Scoring ◽  
Coronary Calcium Scoring ◽  
High Calcium

Cardiac multi-detector computed tomography (MDCT) with retrospective ECG-gating permits the determination and quantification of coronary calcifications. High calcium scores are known to be associated with elevated all-cause mortality. Moreover, low response to clopidogrel influences cardiovascular outcome after coronary stent placement. We sought to evaluate whether elevated calcium scores are associated with a low response to clopidogrel. Methods 62 patients were enrolled in this trial (52 male, mean age 64.8 ± 8.9 years). Coronary calcium scoring (expressed as Agatston score equivalent, ASE) was measured with multi-slice computed tomography (Sensation 64™ [n=19] and Somatom Definition ™ [n=43], Siemens, Forchheim, Germany) prior to stent implantation. Responsiveness to clopidogrel was assessed by ADP (20 micromol/L)-induced aggregometry at least 6 h after administration of a loading dose of 600 mg clopidogrel. Results Median calcium score was 736 ASE [range 0 –3126] and mean platelet inhibition was 35±19% [range 0 –70]. There was a significant negative correlation between ASE and response to clopidogrel (r 2 =0.135, p=0.0033, slope 7.809 ± 2.549). Patients within the first quartile of ASE had significantly better response to clopidogrel than other patients (p<0.05). Establishing a threshold of 200 ASE responsiveness to clopidogrel could be predicted with a positive predictive value of 80% and a specificity of 91%. Conclusions We could demonstrate that elevated ASE is associated with a low response to clopidogrel. Patients with a low coronary plaque burden are more likely to have a good response to clopidogrel. Coronary calcium scoring might help to identify low responders to clopidogrel prior to stent placement and aggregometry.

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