Tube voltage-independent coronary calcium scoring on a first-generation dual-source photon-counting CT—a proof-of-principle phantom study

Author(s):  
V. Mergen ◽  
K. Higashigaito ◽  
T. Allmendinger ◽  
R. Manka ◽  
A. Euler ◽  
...  
2008 ◽  
Vol 25 (4) ◽  
pp. 443-451 ◽  
Author(s):  
Paul Stolzmann ◽  
Sebastian Leschka ◽  
Thomas Betschart ◽  
Lotus Desbiolles ◽  
Thomas G. Flohr ◽  
...  

2020 ◽  
Vol 30 (11) ◽  
pp. 5834-5840
Author(s):  
Vincenzo Vingiani ◽  
Andres F. Abadia ◽  
U. Joseph Schoepf ◽  
Andreas M. Fischer ◽  
Akos Varga-Szemes ◽  
...  

2012 ◽  
Vol 6 (2) ◽  
pp. 113-120 ◽  
Author(s):  
Damini Dey ◽  
Ryo Nakazato ◽  
Raymond Pimentel ◽  
William Paz ◽  
Sean W. Hayes ◽  
...  

2017 ◽  
Vol 69 (11) ◽  
pp. 1560
Author(s):  
Christoph Gräni ◽  
Jan Vontobel ◽  
Dominik Benz ◽  
Sara Bacanovic ◽  
Beatrice Hirt Moch ◽  
...  

2020 ◽  
Vol 30 (6) ◽  
pp. 3346-3355 ◽  
Author(s):  
Ronald Booij ◽  
Niels R. van der Werf ◽  
Ricardo P. J. Budde ◽  
Daniel Bos ◽  
Marcel van Straten

Author(s):  
Hala T. Salem ◽  
Eman A.S. Sabek

Aim and Objective: To estimate the relationship between Coronary Calcium Scoring (CCS)and presence of different degrees of obstructive coronary artery disease (CAD) to avoid unnecessary examinations and hence unnecessary radiation exposure and contrast injection. Background: Coronary Calcium Scoring (CCS) is a test uses x-ray equipment to produce pictures of the coronary arteries to determine the degree of its narrowing by the build-up of calcified plaques. Despite the lack of definitive data linking ionizing radiation with cancer, the American Heart Association supports widely that practitioners of Computed tomography Coronary Angiography (CTCA) should keep “patient radiation doses as low as reasonably achievable but consistent with obtaining the desired medical information”. Methods: Data obtained from 275 CTCA examinations were reviewed. Radiation effective doses were estimated for both CCS and CTCA, measures to keep it as low as possible were presented, CCS and Framingham risk estimate were compared to the final results of CTCA to detect sensitivity and specificity of each one in detecting obstructive lesions. Results: CCS is a strong discriminator for obstructive CAD and can with high sensitivity and specificity and correlates well with the degree of obstruction even more than Framingham risk estimate which has high sensitivity and low specificity. Conclusion: CCS helps reducing the effective radiation dose if properly evaluated to skip unnecessary CTCA if obstructive lesions was unlikely, and as a test does not use contrast material, harmful effect on the kidney will be avoided as most of coronary atherosclerotic patients have renal problems.


Author(s):  
S. Sawall ◽  
L. Klein ◽  
E. Wehrse ◽  
L. T. Rotkopf ◽  
C. Amato ◽  
...  

Abstract Objective To evaluate the dual-energy (DE) performance and spectral separation with respect to iodine imaging in a photon-counting CT (PCCT) and compare it to dual-source CT (DSCT) DE imaging. Methods A semi-anthropomorphic phantom extendable with fat rings equipped with iodine vials is measured in an experimental PCCT. The system comprises a PC detector with two energy bins (20 keV, T) and (T, eU) with threshold T and tube voltage U. Measurements using the PCCT are performed at all available tube voltages (80 to 140 kV) and threshold settings (50–90 keV). Further measurements are performed using a conventional energy-integrating DSCT. Spectral separation is quantified as the relative contrast media ratio R between the energy bins and low/high images. Image noise and dose-normalized contrast-to-noise ratio (CNRD) are evaluated in resulting iodine images. All results are validated in a post-mortem angiography study. Results R of the PC detector varies between 1.2 and 2.6 and increases with higher thresholds and higher tube voltage. Reference R of the EI DSCT is found as 2.20 on average overall phantoms. Maximum CNRD in iodine images is found for T = 60/65/70/70 keV for 80/100/120/140 kV. The highest CNRD of the PCCT is obtained using 140 kV and is decreasing with decreasing tube voltage. All results could be confirmed in the post-mortem angiography study. Conclusion Intrinsically acquired DE data are able to provide iodine images similar to conventional DSCT. However, PCCT thresholds should be chosen with respect to tube voltage to maximize image quality in retrospectively derived image sets. Key Points • Photon-counting CT allows for the computation of iodine images with similar quality compared to conventional dual-source dual-energy CT. • Thresholds should be chosen as a function of the tube voltage to maximize iodine contrast-to-noise ratio in derived image sets. • Image quality of retrospectively computed image sets can be maximized using optimized threshold settings.


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