Assignment of 60 human ESTs in cattle

2000 ◽  
Vol 11 (9) ◽  
pp. 748-754 ◽  
Author(s):  
Pascal Laurent ◽  
Carmen Elduque ◽  
Hélène Hayes ◽  
Katyana Saunier ◽  
André Eggen ◽  
...  
Keyword(s):  
Human Ests

A successful strategy for comparative mapping with human ESTs: 65 new regional assignments in the pig

1999 ◽  
Vol 10 (2) ◽  
pp. 145-153 ◽  
Author(s):  
Yvette Lahbib-Mansais ◽  
Géraldine Dalias ◽  
Denis Milan ◽  
Martine Yerle ◽  
Annie Robic ◽  
...  
Keyword(s):  
Comparative Mapping ◽  
Successful Strategy ◽  
Human Ests

Regional assignment of human ESTs by whole-genome radiation hybrid mapping

1996 ◽  
Vol 7 (6) ◽  
pp. 446-450 ◽  
Author(s):  
P. D. Hayes ◽  
K. Schmitt ◽  
H. B. Jones ◽  
G. Gyapay ◽  
J. Weissenbach ◽  
...  
Keyword(s):  
Radiation Hybrid ◽  
Radiation Hybrid Mapping ◽  
Whole Genome ◽  
Hybrid Mapping ◽  
Human Ests ◽  
Regional Assignment

Differential expression of IGFBP-5 and two human ESTs in thyroid glands with goiter, adenoma and papillary or follicular carcinomas

2003 ◽  
Vol 191 (2) ◽  
pp. 193-202 ◽  
Author(s):  
Beatriz S. Stolf ◽  
Alex F. Carvalho ◽  
Waleska K. Martins ◽  
Franco B. Runza ◽  
Marcel Brun ◽  
...  
Keyword(s):  
Differential Expression ◽  
Thyroid Glands ◽  
Human Ests

Assessing DNA Sequence Variations in Human ESTs in a Phylogenetic Context Using High-Density Oligonucleotide Arrays

Genomics ◽  
2002 ◽  
Vol 80 (3) ◽  
pp. 351-360 ◽  
Author(s):  
Jian-Bing Fan ◽  
Dominik Gehl ◽  
Linda Hsie ◽  
Naiping Shen ◽  
Kerstin Lindblad-Toh ◽  
...  
Keyword(s):  
Dna Sequence ◽  
High Density ◽  
Oligonucleotide Arrays ◽  
Sequence Variations ◽  
Human Ests

scholarly journals Bioinformatic screening of human ESTs for differentially expressed genes in normal and tumor tissues

BMC Genomics ◽  
2006 ◽  
Vol 7 (1) ◽  
Author(s):  
Abdel Aouacheria ◽  
Vincent Navratil ◽  
Audrey Barthelaix ◽  
Dominique Mouchiroud ◽  
Christian Gautier
Keyword(s):  
Differentially Expressed Genes ◽  
Differentially Expressed ◽  
Tumor Tissues ◽  
Human Ests

False association of human ESTs

1994 ◽  
Vol 8 (4) ◽  
pp. 321-322 ◽  
Author(s):  
Jen-Yue Tsai ◽  
Maria L. Namin-Gonzalez ◽  
Lee M. Silver
Keyword(s):  
Human Ests

Characterisation of simple sequence repeats from human ESTs and creation of a comprehensive data base

2010 ◽  
Vol 6 (3) ◽  
pp. 287
Author(s):  
Amit Kumar ◽  
Shakuntala Bulusu ◽  
Vijayalakshmi Kasu ◽  
Kondala Rao
Keyword(s):  
Data Base ◽  
Simple Sequence Repeats ◽  
Comprehensive Data ◽  
Simple Sequence ◽  
Human Ests

scholarly journals Bioinformatic discovery of microRNA precursors from human ESTs and introns

BMC Genomics ◽  
2006 ◽  
Vol 7 (1) ◽  
Author(s):  
Sung-Chou Li ◽  
Chao-Yu Pan ◽  
Wen-chang Lin
Keyword(s):  
Human Ests

scholarly journals Nonrandom variations in human cancer ESTs indicate that mRNA heterogeneity increases during carcinogenesis

2007 ◽  
Vol 104 (18) ◽  
pp. 7522-7527 ◽  
Author(s):  
Marie Brulliard ◽  
Dalia Lorphelin ◽  
Olivier Collignon ◽  
Walter Lorphelin ◽  
Benoit Thouvenot ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Somatic Mutations ◽  
Human Cancer ◽  
Specific Pattern ◽  
Large Set ◽  
Cell Heterogeneity ◽  
Sequence Variations ◽  
Cancer Transcriptome ◽  
Biological Attributes ◽  
Human Ests

Virtually all cancer biological attributes are heterogeneous. Because of this, it is currently difficult to reconcile results of cancer transcriptome and proteome experiments. It is also established that cancer somatic mutations arise at rates higher than suspected, but yet are insufficient to explain all cancer cell heterogeneity. We have analyzed sequence variations of 17 abundantly expressed genes in a large set of human ESTs originating from either normal or cancer samples. We show that cancer ESTs have greater variations than normal ESTs for >70% of the tested genes. These variations cannot be explained by known and putative SNPs. Furthermore, cancer EST variations were not random, but were determined by the composition of the substituted base (b0) as well as that of the bases located upstream (up to b − 4) and downstream (up to b + 3) of the substitution event. The replacement base was also not randomly selected but corresponded in most cases (73%) to a repetition of b − 1 or of b + 1. Base substitutions follow a specific pattern of affected bases: A and T substitutions were preferentially observed in cancer ESTs. In contrast, cancer somatic mutations [Sjoblom T, et al. (2006) Science 314:268–274] and SNPs identified in the genes of the current study occurred preferentially with C and G. On the basis of these observations, we developed a working hypothesis that cancer EST heterogeneity results primarily from increased transcription infidelity.

scholarly journals False association of human ESTs

1994 ◽  
Vol 8 (4) ◽  
pp. 322-322 ◽  
Author(s):  
Mark Adams ◽  
J. Craig Venter
Keyword(s):  
Human Ests
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