Effects of glycemic control on in-hospital mortality among acute heart failure patients with reduced, mid-range, and preserved ejection fraction

2018 ◽  
Vol 33 (9) ◽  
pp. 1022-1028 ◽  
Author(s):  
Kenichi Matsushita ◽  
Kazumasa Harada ◽  
Tetsuro Miyazaki ◽  
Takamichi Miyamoto ◽  
Kiyoshi Iida ◽  
...  
Keyword(s):  
Heart Failure ◽  
Glycemic Control ◽  
Ejection Fraction ◽  
Hospital Mortality ◽  
Acute Heart Failure ◽  
Preserved Ejection Fraction ◽  
Heart Failure Patients

P4512Impact of pulmonary artery catheter on all-cause death of patients with acute heart failure with preserved ejection fraction: Short-term results from the PURSUIT-HFpEF registry

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
N Matsusaki ◽  
Y Sotomi ◽  
T Kobayashi ◽  
T Hayashi ◽  
Y Takeda ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Pulmonary Artery ◽  
Pulmonary Artery Catheter ◽  
Acute Heart Failure ◽  
Death Rate ◽  
Significant Risk ◽  
Preserved Ejection Fraction ◽  
Heart Failure Patients ◽  
Kaplan Meier

Abstract Background Appropriate pulmonary artery catheter (PAC) use may effectively decrease mortality in acute heart failure patients. The concept that the pulmonary artery catheter (PAC) is a valuable tool for hemodynamic monitoring when used in appropriately selected patients and by physicians trained well to interpret and apply the data correctly provided has not been evaluated adequately yet in acute heart failure patients with preserved ejection fraction (HFpEF). Methods The PERSUIT-HFpEF Registry is a prospective, observational, multicenter cohort study on prognosis of HFpEF in Japan. Patients hospitalized for heart failure (diagnosed by using Framingham criteria) who met both of the following criteria were enrolled: 1) a left ventricular ejection fraction of 50% or more as measured at the local site by echocardiography; 2) an elevated level of N terminal pro brain natriuretic peptide (NT proBNP) (400 pg per milliliter or more) or brain natriuretic peptide (BNP) (100 pg per milliliter or more). In the present study, we evaluated the impact of PAC on all-cause death of the patients with HFpEF. PAC use was left at the discretion of attending physicians. Results The PERSUIT-HFpEF Registry enrolled 486 patients (81±9 years, 259 females, mean follow-up duration 198±195 days). Of these, data of PAC usage was available in 434 patients. Patients were further stratified according to use of a PAC: PAC 153 patients vs. non-PAC 281 patients. Length of hospitalization was numerically shorter in the PAC group than in the non-PAC group [20.3±14.7 vs. 22.5±17.4 days, p=0.182]. Kaplan-Meier estimated 1-year all-cause death rate was significantly lower in the PAC group than in the non-PAC group (9.5% vs. 19.1%, p=0.019). PAC use was associated with significant risk reduction of all-cause death [hazard ratio (HR) 0.425, 95% confidence interval (CI), 0.203–0.890, p=0.023] in the crude analysis. The significant risk reduction still existed after multivariate adjustment including potential confounders [HR 0.427, 95% CI, 0.185–0.984, p=0.046] Kaplan Meier analysis Conclusions In the real-world Asian registry data, PAC use was associated with the improved all-cause death rate, suggesting that the PAC might be a useful guidance tool for treatment of the patients with HFpEF. Acknowledgement/Funding Roche diagnostics FUJIFILM Toyama Chemical

scholarly journals Additional value of Galectin-3 to BNP in acute heart failure patients with preserved ejection fraction

2016 ◽  
Vol 457 ◽  
pp. 99-105 ◽  
Author(s):  
Matteo Beltrami ◽  
Gaetano Ruocco ◽  
Amardeep Ghosh Dastidar ◽  
Beatrice Franci ◽  
Barbara Lucani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Acute Heart Failure ◽  
Preserved Ejection Fraction ◽  
Heart Failure Patients ◽  
Galectin 3 ◽  
Additional Value

scholarly journals Management, survival, and predictors of mortality among hospitalized heart failure patients at Debre Markos comprehensive specialized hospital, Northwest Ethiopia: Prospective cohort study

2021 ◽  
Vol 9 ◽  
pp. 205031212110573
Author(s):  
Bekalu Kebe ◽  
Melese Getachew ◽  
Yalew Molla ◽  
Bereket Bahiru ◽  
Bekalu Dessie
Keyword(s):  
Heart Failure ◽  
Cohort Study ◽  
Ejection Fraction ◽  
Hospital Mortality ◽  
Prospective Cohort ◽  
Preserved Ejection Fraction ◽  
Reduced Ejection Fraction ◽  
Heart Failure Patients ◽  
Specialized Hospital ◽  
Debre Markos

Introduction: Heart failure is a major public health problem worldwide. Since heart failure with reduced ejection fraction and preserved ejection fraction are different clinical entities, in-hospital mortality may occur at different rates. This study aimed to assess the management, survival, and predictors of mortality among hospitalized heart failure patients at Debre Markos comprehensive specialized medical ward. Methods: A prospective cohort study was conducted on 228 heart failure patients at Debre Markos Comprehensive Specialized Hospital medical wards. A structured data collection tool was used to collect data. Data were analyzed using SPSS version 21.0. The Kaplan–Meier survival curve was used to investigate if there was a difference in the in-hospital survival between heart failure with a reduced ejection fraction and heart failure with a preserved ejection fraction. Those variables having p-value < 0.05 were considered statistically significant. Results: From the 228 participants, 126 (55.3%) were females with a mean age of 53.32 ± 15.68 years. One hundred thirty-three (58.3%) patients were presented with preserved (⩾50%) level of ejection fraction. The all-cause in-hospital death rate was 12.7%, and the risk of in-hospital mortality was higher in heart failure patients with reduced ejection fraction (7.4% vs 5.3%; p = 0.005). Current occupation ( p = 0.041), elevated serum creatinine ( p = 0.010), reduced ejection fraction ( p = 0.017), and asthma/chronic obstructive pulmonary disease comorbidity ( p = 0.002) were the independent predictors of high hospital mortality. Conclusion: The rate of in-hospital mortality among heart failure patients was high. Healthcare providers should provide effective education activities and define disease management strategies for patients with reduced ejection fractions.

Comparison of demographics and outcomes of acute heart failure patients with reduced, mid-range, and preserved ejection fraction

2020 ◽  
Vol 2 (2) ◽  
pp. 86
Author(s):  
Rajesh Rajan ◽  
Mohammed Al-Jarallah ◽  
Hussein Heshmat ◽  
Ibrahim Al-Zakwani ◽  
Raja Dashti ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Acute Heart Failure ◽  
Preserved Ejection Fraction ◽  
Heart Failure Patients

Acute heart failure with preserved ejection fraction and long-term Readmisions

2008 ◽  
Vol 7 ◽  
pp. 62-63
Author(s):  
J NUNEZ ◽  
L MAINAR ◽  
G MINANA ◽  
R ROBLES ◽  
J SANCHIS ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Acute Heart Failure ◽  
Preserved Ejection Fraction
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