Diurnal pattern of choline concentrations in serum of pigs as influenced by dietary choline or lecithin intake (Diurnaler Verlauf des Serumcholinspiegels beim Schwein nach oraler Applikation von Cholinchlorid oder Lecithin)

1998 ◽  
Vol 37 (4) ◽  
pp. 353-357 ◽  
Author(s):  
S. Jakob ◽  
R. Mosenthin ◽  
G. Huesgen ◽  
J. Kinkeldei ◽  
K.-J. Poweleit
Keyword(s):  
Diurnal Pattern ◽  
Dietary Choline

Diurnal pattern of insulin requirements in insulin-dependent diabetics

1982 ◽  
Vol 42 (1) ◽  
pp. 63-68 ◽  
Author(s):  
E. R. Mathiesen ◽  
P. Rubin ◽  
J. Sandahl Christiansen ◽  
P. Aaby Svendsen ◽  
T. Lauritzen ◽  
...  
Keyword(s):  
Diurnal Pattern ◽  
Insulin Requirements ◽  
Insulin Dependent

Salivary C-reactive protein among at-risk adolescents: A methods investigation of out of range immunoassay data

2018 ◽  
Author(s):  
Elizabeth Landau ◽  
John Arthur Trinder ◽  
Julian Simmons ◽  
Monika Raniti ◽  
Matthew Blake ◽  
...  
Keyword(s):  
At Risk ◽  
Temporal Stability ◽  
Management Technique ◽  
Clinical Settings ◽  
Diurnal Pattern ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Treatment Techniques ◽  
Salivary Biomarker ◽  
At Risk Adolescents

Inflammatory markers including C-Reactive Protein (CRP) are increasingly used within research and clinical settings. Yet, varying methodologies for cleaning immunoassay data with out of range (OOR) samples may alter characteristic levels of CRP, thereby obscuring interpretation and reliability. This study investigated the influence of eight immunoassay OOR data treatment techniques on salivary CRP (sCRP) samples from at-risk adolescents. Participants from the ‘Sleep and Education: learning New Skills Early’ (SENSE) Study were 86 adolescents at-risk for depression (50 female), aged 14.29 years (SD=1.04). ANOVA results showed no statistically significant differences in average morning (F(7, 590)=1.24, p=.28) and evening (F(7, 599)=1.29, p=.25) values produced by each OOR data cleaning technique. However, varying techniques produced differences in the magnitude of Pearson’s correlations between consecutive saliva samples (r’s between .27 – .78), and influenced the significance of a sCRP diurnal pattern; two techniques produced statistically higher morning than evening sCRP levels (t(85)=2.70, p=.01 and t(85)=2.67, p=.01), whereas six techniques failed to find statistical differences between morning and evening sCRP levels (p’s >.05). Varying techniques also produced statistically divergent associations between sCRP and age and depressive symptoms. Results from this study provide evidence for the temporal stability of sCRP among adolescents, show winsorization as an effective OOR data management technique, and highlight the influence of methodological decisions in cleaning salivary biomarker data and the need for consistency within the field.

Dietary Choline Intake during Pregnancy and PEMT rs7946 Polymorphism on Risk of Preterm Birth: A Case-Control Study

2021 ◽  
pp. 1-10
Author(s):  
Jie Zhu ◽  
Yu-Hong Liu ◽  
Xiang-Long He ◽  
Martin Kohlmeier ◽  
Li-Li Zhou ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Case Control Study ◽  
Chinese Women ◽  
Case Control ◽  
Han Chinese ◽  
Food Frequency ◽  
Term Delivery ◽  
Choline Intake ◽  
Dietary Choline ◽  
Control Study

<b><i>Introduction and Aims:</i></b> Choline-metabolizing genetic variation may interact with choline intake on fetal programming and pregnancy outcome. This case-control study aims to explore the association of maternal choline consumption and phosphatidylethanolamine N-methyltransferase (PEMT) gene polymorphism rs7946 with preterm birth risk. <b><i>Methods:</i></b> 145 Han Chinese women with preterm delivery and 157 Han Chinese women with term delivery were recruited in Shanghai. Dietary choline intake during pregnancy was assessed using a validated food frequency questionnaire. Additionally, DNA samples were genotyped for PEMT rs7946 (G5465A) with plasma homocysteine (Hcy) levels measured. <b><i>Results:</i></b> Compared with the lowest quartile of choline intake, women within the highest consumption quartile had adjusted odds ratio (aOR) for preterm birth of 0.48 (95% confidence interval, CI [0.24, 0.95]). There was a significant interaction between maternal choline intake and PEMT rs7946 (<i>p</i> for interaction = 0.04), where the AA genotype carriers who consumed the energy-adjusted choline &#x3c;255.01 mg/day had aOR for preterm birth of 3.75 (95% CI [1.24, 11.35]), compared to those with GG genotype and choline intake &#x3e;255.01 mg/day during pregnancy. Additionally, the greatest elevated plasma Hcy was found in the cases with AA genotype and choline consumption &#x3c;255.01 mg/day (<i>p</i> &#x3c; 0.001). <b><i>Conclusion:</i></b> The AA genotype of PEMT rs7946 may be associated with increased preterm birth in these Han Chinese women with low choline intake during pregnancy.

scholarly journals THE EFFECT OF DIETARY CHOLINE UPON THE RATE OF TURNOVER OF PHOSPHATIDE CHOLINE

1944 ◽  
Vol 153 (2) ◽  
pp. 617-625
Author(s):  
George E. Boxer ◽  
DeWitt Stetten
Keyword(s):  
Dietary Choline

CHRONIC DIETARY CHOLINE & PHOSPHATIDYLCHOLINE INDUCES DENDRITIC GROWTH IN NEURONS OF AGING MOUSE NEOCORTEX

1987 ◽  
Vol 46 (3) ◽  
pp. 340
Author(s):  
R. F. Mervis ◽  
K. L. Parker ◽  
C. L. Byler ◽  
J. El-Yabroudi ◽  
J. A. Sherer ◽  
...  
Keyword(s):  
Dendritic Growth ◽  
Aging Mouse ◽  
Dietary Choline
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