Immunolocalization of NuMA and phosphorylated proteins during the cell cycle in human breast and prostate cancer cells as analyzed by immunofluorescence and postembedding immunoelectron microscopy

2001 ◽  
Vol 115 (5) ◽  
pp. 381-395 ◽  
Author(s):  
Geoffrey N. Gobert ◽  
Christopher N. Hueser ◽  
Edward M. Curran ◽  
Qing-Yuan Sun ◽  
Vladislav V. Glinsky ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Cancer Cells ◽  
Immunoelectron Microscopy ◽  
Human Breast ◽  
Prostate Cancer Cells ◽  
Phosphorylated Proteins ◽  
Breast And Prostate Cancer ◽  
Postembedding Immunoelectron Microscopy

Proliferative effect of whey from cows’ milk varying in phyto-oestrogens in human breast and prostate cancer cells

2012 ◽  
Vol 79 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Tina S. Nielsen ◽  
Annika Höjer ◽  
Anne-Maj Gustavsson ◽  
Jens Hansen-Møller ◽  
Stig Purup
Keyword(s):  
Prostate Cancer ◽  
Cell Proliferation ◽  
Cancer Cells ◽  
Dietary Treatment ◽  
Human Breast ◽  
Prostate Cancer Cells ◽  
Proliferative Effect ◽  
Significant Difference ◽  
Breast And Prostate Cancer ◽  
Mcf 7

Intake of dietary phyto-oestrogens has received a great deal of attention owing to their potential influence on hormone-sensitive cancers such as breast and prostate cancer. Cows’ milk contains phyto-oestrogens and the content varies according to the composition of the feed and the type and amount of legumes used. In this study we evaluated the proliferative effect of milk (whey) with different phyto-oestrogen content in human breast (MCF-7) and prostate cancer cells (PC-3). Milk was obtained from cows fed either a birdsfoot trefoil-timothy silage based ration (B1) or two different red clover silage based diets (R1 and R2) resulting in total phyto-oestrogen contents of 403, 1659 and 1434 ng/ml for the B1, R1 and R2 diets, respectively. Whey was produced from the milk and added to cell culture medium in concentrations up to 10% for MCF-7 cells and 5% for PC-3 cells. Cell proliferation was measured fluorometrically after 7 d for MCF-7 cells and 5 d for PC-3 cells. There was no significant difference in the proliferative effect of whey from the different dietary treatments at any of the whey concentrations tested. An anti-proliferative effect (P<0·01) of 5 and 10% whey was seen when tested in the presence of 10 pmoestradiol in the medium. This effect was independent of dietary treatment of cows. Whey induced a significant (P<0·01) proliferative response in PC-3 cells independent of dietary treatment. Purified equol in concentrations similar to equol concentrations in milk decreased PC-3 cell proliferation, and therefore the stimulatory effect of whey in PC-3 cells is believed to be mediated by other bioactives than equol. In conclusion, our results suggest that using whey in these proliferation assays, it was not possible to discriminate between milk with high or low levels of phyto-oestrogens.

scholarly journals Effects of Vorinostat, Letrozole and RG7388 Treatments on Cell Cycle Arrest and Survival of Breast and Prostate Cancer Cells

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
Umamaheswari Natarajan ◽  
Thiagarajan Venkatesan ◽  
Sivanesa Dhandayuthapani ◽  
Thanigaivelan Kanagasabai ◽  
Shila Samuel Samuel ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Cell Cycle Arrest ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Cycle Arrest ◽  
Breast And Prostate Cancer

Anthocyanins of Blue Corn and Tortilla Arrest Cell Cycle and Induce Apoptosis on Breast and Prostate Cancer Cells

2019 ◽  
Vol 72 (5) ◽  
pp. 768-777 ◽  
Author(s):  
Mónica Y. Herrera-Sotero ◽  
Carlos D. Cruz-Hernández ◽  
Rosa M. Oliart-Ros ◽  
José L. Chávez-Servia ◽  
Rosa I. Guzmán-Gerónimo ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Cancer Cells ◽  
Prostate Cancer Cells ◽  
Breast And Prostate Cancer ◽  
Blue Corn

MnSOD Up-Regulates Maspin Tumor Suppressor Gene Expression in Human Breast and Prostate Cancer Cells

2003 ◽  
Vol 5 (5) ◽  
pp. 677-688 ◽  
Author(s):  
Hong Duan ◽  
Hannah J. Zhang ◽  
Ji-Qin Yang ◽  
Larry W. Oberley ◽  
Bernard W. Futscher ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prostate Cancer ◽  
Tumor Suppressor ◽  
Cancer Cells ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Human Breast ◽  
Prostate Cancer Cells ◽  
Breast And Prostate Cancer

scholarly journals Anticancer activity of a sub-fraction of dichloromethane extract of Strobilanthes crispus on human breast and prostate cancer cells in vitro

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Nik Soriani Yaacob ◽  
Nurraihana Hamzah ◽  
Nik Nursyazni Nik Mohamed Kamal ◽  
Siti Amalina Zainal Abidin ◽  
Choon Sheen Lai ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Human Breast ◽  
Prostate Cancer Cells ◽  
Strobilanthes Crispus ◽  
Breast And Prostate Cancer
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