Concurrent information affects response inhibition processes via the modulation of theta oscillations in cognitive control networks

AbstractNegation is known to have inhibitory consequences for the information under its scope. However, how it produces such effects remains poorly understood. Recently, it has been proposed that negation processing might be implemented at the neural level by the recruitment of inhibitory and cognitive control mechanisms. On this line, this manuscript offers the hypothesis that negation reuses general-domain mechanisms that subserve inhibition in other non-linguistic cognitive functions. The first two sections describe the inhibitory effects of negation on conceptual representations and its embodied effects, as well as the theoretical foundations for the reuse hypothesis. The next section describes the neurophysiological evidence that linguistic negation interacts with response inhibition, along with the suggestion that both functions share inhibitory mechanisms. Finally, the manuscript concludes that the functional relation between negation and inhibition observed at the mechanistic level could be easily integrated with predominant cognitive models of negation processing.

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Adolescent cognitive control and mediofrontal theta oscillations are disrupted by neglect: Associations with transdiagnostic risk for psychopathology in a randomized controlled trial

Developmental Cognitive Neuroscience ◽

10.1016/j.dcn.2020.100777 ◽

2020 ◽

Vol 43 ◽

pp. 100777 ◽

Cited By ~ 1

Author(s):

George A. Buzzell ◽

Sonya V. Troller-Renfree ◽

Mark Wade ◽

Ranjan Debnath ◽

Santiago Morales ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Cognitive Control ◽

Controlled Trial ◽

Theta Oscillations ◽

Randomized Controlled

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935. Acute Cortisol Reactivity is Associated with Increased Connectivity from Default Mode to Cognitive Control Networks in Remitted Adolescent-Onset Depression

Biological Psychiatry ◽

10.1016/j.biopsych.2017.02.661 ◽

2017 ◽

Vol 81 (10) ◽

pp. S378-S379

Author(s):

Amy Peters ◽

Lisanne Jenkins ◽

Jonathan Stange ◽

Katie Bessette ◽

Kristy Skerrett ◽

...

Keyword(s):

Cognitive Control ◽

Cortisol Reactivity ◽

Default Mode ◽

Control Networks

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Neurocognitive mechanisms of cognitive control: The role of prefrontal cortex in action selection, response inhibition, performance monitoring, and reward-based learning

Brain and Cognition ◽

10.1016/j.bandc.2004.09.016 ◽

2004 ◽

Vol 56 (2) ◽

pp. 129-140 ◽

Cited By ~ 812

Author(s):

K. Richard Ridderinkhof ◽

Wery P.M. van den Wildenberg ◽

Sidney J. Segalowitz ◽

Cameron S. Carter

Keyword(s):

Prefrontal Cortex ◽

Cognitive Control ◽

Response Inhibition ◽

Performance Monitoring ◽

Action Selection ◽

Selection Response ◽

Inhibition Performance

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On the interrelation of 1/f neural noise and norepinephrine system activity during motor response inhibition

Journal of Neurophysiology ◽

10.1152/jn.00701.2018 ◽

2019 ◽

Vol 121 (5) ◽

pp. 1633-1643 ◽

Cited By ~ 7

Author(s):

Maik Pertermann ◽

Moritz Mückschel ◽

Nico Adelhöfer ◽

Tjalf Ziemssen ◽

Christian Beste

Keyword(s):

Information Processing ◽

Cognitive Control ◽

Inhibitory Control ◽

Response Inhibition ◽

Pupil Diameter ◽

Human Information Processing ◽

System Activity ◽

Neural Noise ◽

Control Processes ◽

Norepinephrine System

Several lines of evidence suggest that there is a close interrelation between the degree of noise in neural circuits and the activity of the norepinephrine (NE) system, yet the precise nexus between these aspects is far from being understood during human information processing and cognitive control in particular. We examine this nexus during response inhibition in n = 47 healthy participants. Using high-density EEG recordings, we estimate neural noise by calculating “1/ f noise” of those data and integrate these EEG parameters with pupil diameter data as an established indirect index of NE system activity. We show that neural noise is reduced when cognitive control processes to inhibit a prepotent/automated response are exerted. These neural noise variations were confined to the theta frequency band, which has also been shown to play a central role during response inhibition and cognitive control. There were strong positive correlations between the 1 /f neural noise parameter and the pupil diameter data within the first 250 ms after the Nogo stimulus presentation at centro-parietal electrode sites. No such correlations were evident during automated responding on Go trials. Source localization analyses using standardized low-resolution brain electromagnetic tomography show that inferior parietal areas are activated in this time period in Nogo trials. The data suggest an interrelation of NE system activity and neural noise within early stages of information processing associated with inferior parietal areas when cognitive control processes are required. The data provide the first direct evidence for the nexus between NE system activity and the modulation of neural noise during inhibitory control in humans. NEW & NOTEWORTHY This is the first study showing that there is a nexus between norepinephrine system activity and the modulation of neural noise or scale-free neural activity during inhibitory control in humans. It does so by integrating pupil diameter data with analysis of EEG neural noise.

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Cognitive Control Processes and Defense Mechanisms That Influence Aggressive Reactions: Toward an Integration of Socio-Cognitive and Psychodynamic Models of Aggression

Frontiers in Human Neuroscience ◽

10.3389/fnhum.2021.751336 ◽

2022 ◽

Vol 15 ◽

Author(s):

Jean Gagnon ◽

Joyce Emma Quansah ◽

Paul McNicoll

Keyword(s):

Cognitive Control ◽

Response Inhibition ◽

Defense Mechanisms ◽

Stop Signal Task ◽

Psychological Processes ◽

N400 Effect ◽

Defense Style ◽

Prepotent Response ◽

Aversive Behavior ◽

Critical Words

Research on cognitive processes has primarily focused on cognitive control and inhibitory processes to the detriment of other psychological processes, such as defense mechanisms (DMs), which can be used to modify aggressive impulses as well as self/other images during interpersonal conflicts. First, we conducted an in-depth theoretical analysis of three socio-cognitive models and three psychodynamic models and compared main propositions regarding the source of aggression and processes that influence its enactment. Second, 32 participants completed the Hostile Expectancy Violation Paradigm (HEVP) in which scenarios describe a hostile vs. non-hostile social context followed by a character's ambiguous aversive behavior. The N400 effect to critical words that violate expected hostile vs. non-hostile intent of the behavior was analyzed. Prepotent response inhibition was measured using a Stop Signal task (SST) and DMs were assessed with the Defense Style Questionnaire (DSQ-60). Results showed that reactive aggression and HIA were not significantly correlated with response inhibition but were significantly positively and negatively correlated with image distorting defense style and adaptive defense style, respectively. The present article has highlighted the importance of integrating socio-cognitive and psychodynamic models to account for the full complexity underlying psychological processes that influence reactive aggressive behavior.

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Alcohol Hangover Slightly Impairs Response Selection but not Response Inhibition

Journal of Clinical Medicine ◽

10.3390/jcm8091317 ◽

2019 ◽

Vol 8 (9) ◽

pp. 1317 ◽

Cited By ~ 5

Author(s):

Antje Opitz ◽

Jan Hubert ◽

Christian Beste ◽

Ann-Kathrin Stock

Keyword(s):

Cognitive Control ◽

Response Inhibition ◽

Response Selection ◽

Current Knowledge ◽

Alcohol Intoxication ◽

Heavy Drinking ◽

High Dose ◽

Automatic Response ◽

Alcoholic Drinks ◽

Alcohol Hangover

Alcohol hangover commonly occurs after an episode of heavy drinking. It has previously been demonstrated that acute high-dose alcohol intoxication reduces cognitive control, while automatic processes remain comparatively unaffected. However, it has remained unclear whether alcohol hangover, as a consequence of binge drinking, modulates the interplay between cognitive control and automaticity in a comparable way. Therefore, the purpose of this study was to investigate the effects of alcohol hangover on controlled versus automatic response selection and inhibition. N = 34 healthy young men completed a Simon Nogo task, once sober and once hungover. Hangover symptoms were experimentally induced by a standardized administration of alcoholic drinks (with high congener content) on the night before the hangover appointment. We found no significant hangover effects, which suggests that alcohol hangover did not produce the same functional deficits as an acute high-dose intoxication. Yet still, add-on Bayesian analyses revealed that hangover slightly impaired response selection, but not response inhibition. This pattern of effects cannot be explained with the current knowledge on how ethanol and its metabolite acetaldehyde may modulate response selection and inhibition via the dopaminergic or GABAergic system.

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