scholarly journals Reproductive risks in 35-year-old adults born very preterm and/or with very low birth weight: an observational study

2020 ◽  
Author(s):  
Sylvia M. van der Pal ◽  
Sanne A. van der Meulen ◽  
Sophie M. Welters ◽  
Leonhard A. Bakker ◽  
Christianne J. M. de Groot ◽  
...  
Keyword(s):  
Birth Weight ◽  
Pregnancy Complications ◽  
Very Low Birth Weight ◽  
Reproductive Rate ◽  
Elevated Risk ◽  
Dutch Population ◽  
Very Preterm ◽  
Increased Risk ◽  
General Dutch Population ◽  
Fertility Problems

Abstract Evidence suggests that increased survival over the last decades of very preterm (VPT; gestational age < 32 weeks)– and very low birth weight (VLBW; birth weight < 1500 g)–born infants is not matched by improved outcomes. The objective of our study was to evaluate the reproductive rate, fertility, and pregnancy complications in 35-year-old VPT/VLBW subjects. All Dutch VPT/VLBW infants born alive in 1983 and surviving until age 35 (n = 955) were eligible for a POPS-35 study. A total of 370 (39%) subjects completed a survey on reproductive rate, fertility problems, pregnancy complications, and perinatal outcomes of their offspring. We tested differences in these parameters between the VPT/VLBW subjects and their peers from Dutch national registries. POPS-35 participants had less children than their peers in the CBS registry. They reported more problems in conception and pregnancy complications, including a three times increased risk of hypertension during pregnancy. Conclusion: Reproduction is more problematic in 35-year olds born VPT/VLBW than in the general population, possibly mediated by an increased risk for hypertension, but their offspring have no elevated risk for preterm birth. What is known:At age 28, the Dutch national POPS cohort, born very preterm or with a very low birth in 1983, had lower reproductive rates than the general Dutch population (female 23% versus 32% and male 7% versus 22%).What is new:At age 35, the Dutch POPS cohort still had fewer children than the general Dutch population (female 56% versus 74% and male 40% versus 56%). Females in the POPS cohort had a higher risk of fertility problems and pregnancy complications than their peers in the Dutch national registries, but their offspring had no elevated risk for preterm birth.

scholarly journals Clinical profile and factors determining outcome of intramural very low birth weight babies in a tertiary care centre: a retrospective study

2017 ◽  
Vol 5 (2) ◽  
pp. 520
Author(s):  
Devi Meenakshi K. ◽  
Arasar Seeralar A. T. ◽  
Srinivasan Padmanaban
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Logistic Regression Analysis ◽  
Very Low Birth Weight ◽  
Tertiary Care ◽  
P Value ◽  
Increased Risk

Background: Very low birth weight (VLBW) babies are at increased risk of a number of complications both immediate and late. Worldwide it has been observed that these babies contribute to a significant extent to neonatal mortality and morbidity. Aim of the study was to study the risk factors contributing to mortality in VLBW babies and to evaluate the morbidity pattern in these infants.Methods: A retrospective analysis of data retrieved from the case records of VLBW babies admitted in the NICU of Kilpauk Medical College between January 2015 to December 2015. Out of the 2360 intramural babies admitted during the study period, 99 babies were less than 1500 gms. The risk factors for these babies were analyzed for their association with the outcome. Data were statistically analyzed.Results: In present study, we found that sex of the baby, gestational age, obstetric score, birth asphyxia, pulmonary haemorrhage, ROP and presence of shock were found to be associated with increased mortality. By logistic regression analysis it was observed that birth weight of the baby (p value 0.002), duration of stay (p value 0.0006), presence of shock (p<0.0001), were the risk factors significantly associated with poor outcome.Conclusions: Among the maternal and neonatal factors analyzed in the study using logistic regression analysis, birth weight, duration of hospital stay and presence of shock were significantly related to poor outcome. Of these presence of shock was the single most important factor that predicted increased mortality.

scholarly journals Strabismus in very low birth weight and/or very preterm children: Discrepancy between age of onset and start of treatment

1995 ◽  
Vol 154 (3) ◽  
pp. 225-229 ◽  
Author(s):  
J. W. R. Pott ◽  
J. Van Hof-van Duin ◽  
I. J. Heersema ◽  
W. P. F. Fetter ◽  
A. M. Schreuder ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Age Of Onset ◽  
Preterm Children ◽  
Very Preterm

scholarly journals Impaired Language Abilities and White Matter Abnormalities in Children Born Very Preterm and/or Very Low Birth Weight

2013 ◽  
Vol 162 (4) ◽  
pp. 719-724 ◽  
Author(s):  
Natalie Reidy ◽  
Angela Morgan ◽  
Deanne K. Thompson ◽  
Terrie E. Inder ◽  
Lex W. Doyle ◽  
...  
Keyword(s):  
Birth Weight ◽  
White Matter ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Language Abilities ◽  
White Matter Abnormalities ◽  
Very Preterm

A meta-analysis of neonatal health outcomes from oocyte donation

2015 ◽  
Vol 7 (3) ◽  
pp. 257-272 ◽  
Author(s):  
D. H. Adams ◽  
R. A. Clark ◽  
M. J. Davies ◽  
S. de Lacey
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Health Outcomes ◽  
Very Low Birth Weight ◽  
Meta Analysis ◽  
Oocyte Donation ◽  
Donor Oocyte ◽  
Cochrane Reviews ◽  
Increased Risk ◽  
Weight Outcomes

Donated oocytes are a treatment modality for female infertility which is also associated with increased risks of preeclampsia. Subsequently it is important to evaluate if there is concomitant increased risks for adverse neonatal events in donated oocyte neonates. A structured search of the literature using PubMed, EMBASE and Cochrane Reviews was performed to investigate the perinatal health outcomes of offspring conceived from donor oocytes compared with autologous oocytes. Meta-analysis was performed on comparable outcomes data. Twenty-eight studies were eligible and included in the review, and of these, 23 were included in a meta-analysis. Donor oocyte neonates are at increased risk of being born with low birth weight (<2500 g) [risk ratio (RR): 1.18, 95% confidence interval (CI): 1.14–1.22, P-value (P)<0.00001], very low birth weight (<1500 g) (RR: 1.24, CI: 1.15–1.35, P<0.00001), preterm (<37 weeks) (RR: 1.26, CI: 1.23–1.30, P<0.00001), of lower gestational age (mean difference −0.3 weeks, CI: −0.35 weeks to −0.25 weeks, P<0.00001), and preterm with low birth weight (RR: 1.24, CI: 1.19–1.29, P<0.00001), when compared with autologous oocyte neonates. Conversely, low birth weight outcomes were improved in term donor oocyte neonates (RR: 0.86, CI: 0.8–0.93, P=0.0003). These negative outcomes remained significant when controlling for multiple deliveries. The donor oocyte risk rates are higher than those found in general ART outcomes, are important considerations for the counselling of infertile patients and may also influence the long term health of the offspring.

scholarly journals Prognostic Factors for Behavioral Problems and Psychiatric Disorders in Children Born Very Preterm or Very Low Birth Weight

2016 ◽  
Vol 37 (1) ◽  
pp. 88-102 ◽  
Author(s):  
Louise Linsell ◽  
Reem Malouf ◽  
Samantha Johnson ◽  
Joan Morris ◽  
Jennifer J. Kurinczuk ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Psychiatric Disorders ◽  
Behavioral Problems ◽  
Very Low Birth Weight ◽  
Very Preterm

scholarly journals Association of Maternal Diabetes With Neonatal Outcomes of Very Preterm and Very Low-Birth-Weight Infants

2018 ◽  
Vol 172 (9) ◽  
pp. 867 ◽  
Author(s):  
Martina Persson ◽  
Prakesh S. Shah ◽  
Franca Rusconi ◽  
Brian Reichman ◽  
Neena Modi ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Maternal Diabetes ◽  
Neonatal Outcomes ◽  
Low Birth Weight Infants ◽  
Very Preterm
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