The effect of blood transfusion and haemodilution on cerebral oxygenation and haemodynamics in newborn infants investigated by near infrared spectrophotometry

1997 ◽  
Vol 156 (4) ◽  
pp. 305-310 ◽  
Author(s):  
K. D. Liem ◽  
J. C. W. Hopman ◽  
B. Oeseburg ◽  
A. F. J. de Haan ◽  
L. A. A. Kollée
Keyword(s):  
Blood Transfusion ◽  
Near Infrared ◽  
Cerebral Oxygenation ◽  
Newborn Infants ◽  
Infrared Spectrophotometry

scholarly journals 119 CONTINUOUS NON-INVASIVE MONITORING OF CEREBRAL OXYGENATION IN SICK NEWBORN INFANTS BY NEAR INFRARED SPECTROPHOTOMETRY

1986 ◽  
Vol 20 (10) ◽  
pp. 1053-1053
Author(s):  
J S Wyatt ◽  
M Cope ◽  
D T Delpy ◽  
S Wray ◽  
E O R Reynolds
Keyword(s):  
Near Infrared ◽  
Cerebral Oxygenation ◽  
Newborn Infants ◽  
Invasive Monitoring ◽  
Infrared Spectrophotometry ◽  
Non Invasive ◽  
Sick Newborn

scholarly journals Cerebral Oxygenation and Hemodynamics During Induction of Extracorporeal Membrane Oxygenation as Investigated by Near Infrared Spectrophotometry

PEDIATRICS ◽  
1995 ◽  
Vol 95 (4) ◽  
pp. 555-561
Author(s):  
K. D. Liem ◽  
J. C. W. Hopman ◽  
B. Oeseburg ◽  
A. F. J. de Haan ◽  
C. Festen ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Blood Volume ◽  
Near Infrared ◽  
Cerebral Blood Volume ◽  
Cerebral Oxygenation ◽  
Cerebral Arteries ◽  
Newborn Infants ◽  
Infrared Spectrophotometry ◽  
Membrane Oxygenation ◽  
Before And After

Objective. To investigate cerebral oxygenation and hemodynamics in relation to changes in some relevant physiologic variables during induction of extracorporeal membrane oxygenation (ECMO) in newborn infants. Methods. Twenty-four newborn infants requiring ECMO were studied from cannulation until 60 minutes after starting ECMO. Concentration changes of oxyhemoglobin (cO2Hb), deoxyhemoglobin (cHHb), total hemoglobin (ctHb), and (oxidized-reduced) cytochrome aa3 (cCyt.aa3) in cerebral tissue were measured continuously by near infrared spectrophotometry. Heart rate (HR), transcutaneous partial pressures of oxygen and carbon dioxide (tcPo2 and tcPco2), arterial O2 saturation (saO2), and mean arterial blood pressure (MABP) were measured simultaneously. Intravascular hemoglobin concentration (cHb) was measured before and after starting ECMO. In 18 of the 24 infants, mean blood flow velocity (MBFV) and pulsatility index (PI) in the internal carotid and middle cerebral arteries were also measured before and after starting ECMO using pulsed Doppler ultrasound. Results. After carotid ligation, cO2Hb decreased whereas cHHb increased. After jugular ligation, no changes in cerebral oxygenation were found. At 60 minutes after starting ECMO, the values of cO2Hb, saO2, tcPo2, and MABP were significantly higher than the precannulation values, whereas the value of cHHb was lower. There were no changes in cCyt.aa3, tcPco2, and HR, whereas cHb, decreased. The MBFV was significantly increased in the major cerebral arteries except the right middle cerebral artery, whereas PI was decreased in all measured arteries. Cerebral blood volume, calculated from changes in ctHb and cHb, was increased in 20 of 24 infants after starting ECMO. Using multivariate regression models, a positive correlation of ΔctHb (representative of changes in cerebral blood volume) with ΔMABP and a negative correlation with ΔtcPo2 were found. Conclusions. The alterations in cerebral oxygenation after carotid artery ligation might reflect increased O2 extraction. Despite increase of the cerebral O2 supply after starting ECMO, no changes in intracellular O2 availability were found, probably because of sufficient preservation of intracellular cerebral oxygenation in the pre-ECMO period despite prolonged hypoxemia. The increase in cerebral blood volume and cerebral MBFV may result from the following: (1) reactive hyperperfusion, (2) loss of autoregulation because of prolonged hypoxemia before ECMO and/or decreased arterial pulsatility, or (3) compensation for hemodilution related to the ECMO procedure.

QUANTIFICATION OF CEREBRAL OXYGENATION AND HAEMODYNAMICS IN SICK NEWBORN INFANTS BY NEAR INFRARED SPECTROPHOTOMETRY

The Lancet ◽  
1986 ◽  
Vol 328 (8515) ◽  
pp. 1063-1066 ◽  
Author(s):  
J.S. Wyatt ◽  
D.T. Delpy ◽  
M. Cope ◽  
Susan Wray ◽  
E.O.R. Reynolds
Keyword(s):  
Near Infrared ◽  
Cerebral Oxygenation ◽  
Newborn Infants ◽  
Infrared Spectrophotometry ◽  
Sick Newborn

Episodes of apnea and bradycardia in the preterm newborn: impact on cerebral oxygenation measured by near-infrared spectrophotometry

1998 ◽  
Author(s):  
Sabine Van Huffel ◽  
Johan Craemers ◽  
Bart Lenaerts ◽  
Hans Daniels ◽  
Gunnar Naulaers ◽  
...  
Keyword(s):  
Near Infrared ◽  
Cerebral Oxygenation ◽  
Preterm Newborn ◽  
Infrared Spectrophotometry

Cerebral oxygenation determined by near-infrared spectrophotometry in patients with fulminant hepatic failure

2003 ◽  
Vol 38 (2) ◽  
pp. 188-192 ◽  
Author(s):  
Henning Bay Nielsen ◽  
Flemming Tofteng ◽  
Lars Peter Wang ◽  
Fin Stolze Larsen
Keyword(s):  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Near Infrared ◽  
Cerebral Oxygenation ◽  
Infrared Spectrophotometry
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