Identification and genetic characterization of the Pseudomonas aeruginosaleuB gene encoding 3-isopropylmalate dehydrogenase

Streptococcal toxic shock syndrome (STSS) caused by Streptococcus pyogenes emm 89 strains has been increasing in several countries and reported to be linked with a recently emerged clade of emm89 strains, designated clade 3. In Japan, epidemiological and genetic information for emm89 strains remains elusive. In this study, we utilized emm89 strains isolated from both STSS (89 isolates) and non-STSS (72 isolates) infections in Japan from 2011 to 2019, and conducted whole-genome sequencing and comparative analysis, which resulted in classification of a large majority into clade 3 regardless of disease severity. In addition, STSS-associated genes and SNPs were found in clade 3 strains, including mutations of streptokinase (Ska), control of virulence sensor (CovS), serum opacity factor (SOF), sortase (SrtB), and fibronectin-binding protein F1 (PrtF1), and absence of the hylP1 gene encoding hyaluronidase. These findings provide insights into notable genetic features of emm89 strains.

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Genetic Characterization of the Gene Encoding Ferredoxin II from the Nitrogen Fixing Phototrophic Bacterium Rhodobacter Capsulatus

Nitrogen Fixation ◽

10.1007/978-94-011-3486-6_129 ◽

1991 ◽

pp. 577-578

Author(s):

C. Duport ◽

Y. Jouanneau ◽

P. M. Vignais

Keyword(s):

Rhodobacter Capsulatus ◽

Genetic Characterization ◽

Nitrogen Fixing ◽

Gene Encoding ◽

Phototrophic Bacterium

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GENETIC CHARACTERIZATION OF THE REGION BETWEEN 86F1,2 AND 87B15 ON CHROMOSOME 3 OF DROSOPHILA MELANOGASTER

Genetics ◽

10.1093/genetics/98.4.775 ◽

1981 ◽

Vol 98 (4) ◽

pp. 775-789

Author(s):

J Gausz ◽

H Gyurkovics ◽

G Bencze ◽

A A M Awad ◽

J J Holden ◽

...

Keyword(s):

Drosophila Melanogaster ◽

Heat Shock ◽

Genetic Characterization ◽

Chromosome 3 ◽

Gene Encoding ◽

Lethal Mutations ◽

Complementation Groups ◽

Shock Locus ◽

Chromosome Bands

ABSTRACT The region between 86F1,2 and 87B15 on chromosome 3 of Drosophila melanogaster, which contains about 27 polytene chromosome bands including the 87A7 heat-shock locus, has been screened for EMS-induced visible and lethal mutations. We have recovered 268 lethal mutations that fall into 25 complementation groups. Cytogenetic localization of the complementation groups by deficiency mapping is consistent with the notion that each band encodes a single genetic function. We have also screened for mutations at the 87A7 heat shock locus, using a chromosome that has only one copy of the gene encoding the 70,000 dalton heat-shock protein (hsp70). No lethal or visible mutations at 87A7 were identified from 10,719 mutagenized chromosomes, and no female-sterile mutations at 87A7 were recovered from the 1,520 chromosomes whose progeny were tested for female fertility. We found no evidence that a functional hsp70 gene is required for development under laboratory conditions.

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Sequencing, expression, and genetic characterization of the Helicobacter pylori ftsH gene encoding a protein homologous to members of a novel putative ATPase family.

Journal of Bacteriology ◽

10.1128/jb.178.21.6151-6157.1996 ◽

1996 ◽

Vol 178 (21) ◽

pp. 6151-6157 ◽

Cited By ~ 23

Author(s):

Z Ge ◽

D E Taylor

Keyword(s):

Helicobacter Pylori ◽

Genetic Characterization ◽

Gene Encoding

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Genetic Characterization of Mutants Resistant to the Antiauxin p-Chlorophenoxyisobutyric Acid Reveals That AAR3, a Gene Encoding a DCN1-Like Protein, Regulates Responses to the Synthetic Auxin 2,4-Dichlorophenoxyacetic Acid in Arabidopsis Roots

PLANT PHYSIOLOGY ◽

10.1104/pp.107.104844 ◽

2007 ◽

Vol 145 (3) ◽

pp. 773-785 ◽

Cited By ~ 32

Author(s):

Kamal Kanti Biswas ◽

Chiharu Ooura ◽

Kanako Higuchi ◽

Yuji Miyazaki ◽

Vinh Van Nguyen ◽

...

Keyword(s):

Genetic Characterization ◽

Dichlorophenoxyacetic Acid ◽

Gene Encoding ◽

Synthetic Auxin ◽

2,4 Dichlorophenoxyacetic Acid ◽

Chlorophenoxyisobutyric Acid

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Histopathological and genetic characterization of colorectal mucinous carcinoma

Gastroenterology ◽

10.1016/s0016-5085(01)80821-0 ◽

2001 ◽

Vol 120 (5) ◽

pp. A166-A166

Author(s):

S FUJII ◽

T KUSAKA ◽

T KAIHARA ◽

Y UEDA ◽

T CHIBA ◽

...

Keyword(s):

Genetic Characterization ◽

Mucinous Carcinoma

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Genetic characterization of high hyperdiploidy in childhood acute lymphoblastic leukemia

Klinische Pädiatrie ◽

10.1055/s-0029-1222694 ◽

2009 ◽

Vol 221 (03) ◽

Author(s):

R Vagkopoulou ◽

C Eckert ◽

U Ungethüm ◽

G Körner ◽

M Stanulla ◽

...

Keyword(s):

Acute Lymphoblastic Leukemia ◽

Genetic Characterization ◽

Lymphoblastic Leukemia ◽

Childhood Acute Lymphoblastic Leukemia

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TBE in Sweden

Tick-borne encephalitis - The Book ◽

10.33442/26613980_12b32-3 ◽

2020 ◽

Keyword(s):

Genetic Characterization ◽

Immunoglobulin M ◽

Enzyme Linked Immunosorbent Assay ◽

Second Phase ◽

Serum Samples ◽

Tick Borne Encephalitis ◽

Specific Immunoglobulin ◽

Tick Borne Encephalitis Virus ◽

First Time

Tick-borne encephalitis virus (TBEV) was isolated for the first time in Sweden in 1958 (from ticks and from 1 tick-borne encephalitis [TBE] patient).1 In 2003, Haglund and colleagues reported the isolation and antigenic and genetic characterization of 14 TBEV strains from Swedish patients (samples collected 1991–1994).2 The first serum sample, from which TBEV was isolated, was obtained 2–10 days after onset of disease and found to be negative for anti-TBEV immunoglobulin M (IgM) by enzyme-linked immunosorbent assay (ELISA), whereas TBEV-specific IgM (and TBEV-specific immunoglobulin G/cerebrospinal fluid [IgG/CSF] activity) was demonstrated in later serum samples taken during the second phase of the disease.

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