scholarly journals Identification of reaction networks for bioprocesses: determination of a partially unknown pseudo-stoichiometric matrix

2005 ◽  
Vol 27 (5) ◽  
pp. 293-301 ◽  
Author(s):  
Olivier Bernard ◽  
Georges Bastin
Keyword(s):  
Reaction Networks ◽  
Stoichiometric Matrix

scholarly journals Energy-based analysis of biomolecular pathways

2017 ◽  
Vol 473 (2202) ◽  
pp. 20160825 ◽  
Author(s):  
Peter J. Gawthrop ◽  
Edmund J. Crampin
Keyword(s):  
Reaction Rates ◽  
Reaction Networks ◽  
Cycle Model ◽  
Stoichiometric Matrix ◽  
Transporter Protein ◽  
Biomolecular Networks ◽  
Energy Flows ◽  
Powerful Approach ◽  
Mass Flows ◽  
Glucose Transport Protein

Decomposition of biomolecular reaction networks into pathways is a powerful approach to the analysis of metabolic and signalling networks. Current approaches based on analysis of the stoichiometric matrix reveal information about steady-state mass flows (reaction rates) through the network. In this work, we show how pathway analysis of biomolecular networks can be extended using an energy-based approach to provide information about energy flows through the network. This energy-based approach is developed using the engineering-inspired bond graph methodology to represent biomolecular reaction networks. The approach is introduced using glycolysis as an exemplar; and is then applied to analyse the efficiency of free energy transduction in a biomolecular cycle model of a transporter protein [sodium-glucose transport protein 1 (SGLT1)]. The overall aim of our work is to present a framework for modelling and analysis of biomolecular reactions and processes which considers energy flows and losses as well as mass transport.

scholarly journals Determination of causal connectivities of species in reaction networks

2002 ◽  
Vol 99 (9) ◽  
pp. 5816-5821 ◽  
Author(s):  
W. Vance ◽  
A. Arkin ◽  
J. Ross
Keyword(s):  
Reaction Networks

A Positive Real Eigenvalue Condition for the Determination of Unstable Steady States in Chemical Reaction Networks

2008 ◽  
Vol 63 (12) ◽  
pp. 778-790
Author(s):  
An-Chong Chao ◽  
Hsing-Ya Li ◽  
Guo-Syong Chuang ◽  
Pang-Yen Ho
Keyword(s):  
Steady State ◽  
Chemical Reaction ◽  
Steady States ◽  
Reaction Networks ◽  
Real Eigenvalue ◽  
Multiple Steady States ◽  
Positive Real ◽  
Unstable Steady State ◽  
Eigenvalue Condition

The interesting dynamical behaviours exhibiting in chemical reaction systems, such as multiple steady states and undamped oscillations, often result from unstable steady states. A positive real eigenvalue condition is proposed which gives a necessary and sufficient condition for the determination of an unstable steady state having a positive real eigenvalue in general isothermal reaction networks. Formulas are developed to construct an unstable steady state and a set of positive rate constants. The applications are illustrated by three examples. Two give rise to oscillations and one admits multiple steady states.

Galactic orbits of stars

1966 ◽  
Vol 25 ◽  
pp. 93-97
Author(s):  
Richard Woolley
Keyword(s):  
Globular Cluster ◽  
Potential Field ◽  
High Velocity ◽  
Velocity Vector ◽  
Variable Stars ◽  
The Sun ◽  
Proper Motions ◽  
Rr Lyrae ◽  
The Galaxy

It is now possible to determine proper motions of high-velocity objects in such a way as to obtain with some accuracy the velocity vector relevant to the Sun. If a potential field of the Galaxy is assumed, one can compute an actual orbit. A determination of the velocity of the globular clusterωCentauri has recently been completed at Greenwich, and it is found that the orbit is strongly retrograde in the Galaxy. Similar calculations may be made, though with less certainty, in the case of RR Lyrae variable stars.

Distance to SN 1987A and the LMC

1999 ◽  
Vol 190 ◽  
pp. 549-554
Author(s):  
Nino Panagia
Keyword(s):  
Angular Size ◽  
Large Magellanic Cloud ◽  
Magellanic Cloud ◽  
Light Curves ◽  
Distance Modulus ◽  
Absolute Size ◽  
Sn 1987A

Using the new reductions of the IUE light curves by Sonneborn et al. (1997) and an extensive set of HST images of SN 1987A we have repeated and improved Panagia et al. (1991) analysis to obtain a better determination of the distance to the supernova. In this way we have derived an absolute size of the ringRabs= (6.23 ± 0.08) x 1017cm and an angular sizeR″ = 808 ± 17 mas, which give a distance to the supernovad(SN1987A) = 51.4 ± 1.2 kpc and a distance modulusm–M(SN1987A) = 18.55 ± 0.05. Allowing for a displacement of SN 1987A position relative to the LMC center, the distance to the barycenter of the Large Magellanic Cloud is also estimated to bed(LMC) = 52.0±1.3 kpc, which corresponds to a distance modulus ofm–M(LMC) = 18.58±0.05.

International determination of the total motion of the pole

1961 ◽  
Vol 13 ◽  
pp. 29-41
Author(s):  
Wm. Markowitz
Keyword(s):  
Secular Motion ◽  
The Future

A symposium on the future of the International Latitude Service (I. L. S.) is to be held in Helsinki in July 1960. My report for the symposium consists of two parts. Part I, denoded (Mk I) was published [1] earlier in 1960 under the title “Latitude and Longitude, and the Secular Motion of the Pole”. Part II is the present paper, denoded (Mk II).

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