Use of the Muscle Pump Activator* for Increasing Lower Limb Venous Flow Velocity

Objective: To demonstrate the effect of a newly developed device, the Muscle Pump Activator, on venous flow velocity of the lower limbs. Design: Prospective study. Setting: Tertiary-care teaching hospital. Subjects: A group of 30 healthy volunteers. Interventions: The Muscle Pump Activator is a self-activated pedal device for use in the sitting position. Venous flow velocity was measured by duplex examination of the femoral vein at rest and during activation by the subject of the device. Subjective reports were also collected. Results: Venous flow velocity increased from 13.3 (SD 2.4) cm/s at rest to a maximum of 70.3 (SD 14.4) cm/s during 15 s of pedalling ( p<0.01). This represents an increase in flow of 439 (SD 12.4)%. Ease of use and comfort of the device were reported by all the volunteers. Conclusions: This Muscle Pump Activator significantly improves venous flow velocity and holds promise as a useful adjunctive modality for the prevention of postoperative deep vein thrombosis. It is easy to use and well tolerated. Studies are now needed in clincial settings with large groups of patients.

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The effects of the combination of angiotensin-converting enzyme inhibitor and diuretic on the lower limb venous circulation in men with hypertension and chronic venous disorders

Russian Journal of Cardiology ◽

10.15829/1560-4071-2020-3-3545 ◽

2020 ◽

Vol 25 (3) ◽

pp. 3545

Author(s):

S. V. Letyagina ◽

V. M. Baev ◽

S. A. Shmeleva ◽

T. Yu. Agafonova

Keyword(s):

Angiotensin Converting Enzyme ◽

Flow Velocity ◽

Antihypertensive Therapy ◽

Lower Limb ◽

Ace Inhibitor ◽

Venous Pressure ◽

Uncontrolled Hypertension ◽

Converting Enzyme ◽

Venous Circulation ◽

Venous Disorders

Aim. To study the effects of angiotensin converting enzyme (ACE) inhibitor and diuretic combination on the lower limb venous circulation in men with hypertension (HTN) and chronic venous disorders (CVD).Material and methods. The study included 37 men with uncontrolled hypertension at the age of 46 (40-49) years, which were divided into two groups: 20 patients with objective signs of CVD (CEAP criteria) and 17 patients without CVD. During hospitalization, all participants received antihypertensive therapy with a combination of ACE inhibitor and diuretic. Vein Doppler ultrasound at rest was performed on the day of hospitalization and after 14 days. The diameter and the area of vein lumen, flow velocity and peripheral venous pressure (PVP) were recorded. Mann-Whitney and Wilcoxon tests were used for statistical analysis.Results. Initially, patients with CVD had higher values of PBP (by 26%), diameter and area of the vein lumen (53%) and flow velocity (by 14%) than in patients without CVD. As a result of therapy, in the group of patients with HTN and without CVD, systolic (SBP) and diastolic blood pressure (DBP) decreased to the target levels, PVP decreased by 13%, vein diameter increased by 27%, blood flow velocity decreased by 15%. Therapy in patients with CVD led to the normalization of SBP, DBP, and a decrease in PVP and flow velocity by 31% and 33%, respectively. No significant changes in the diameter and cross-sectional area of lower limb veins were noted.Conclusion. The obtained data showed that 14-day antihypertensive therapy with ACE inhibitor and diuretic in patients with HTN and CVD, unlike patients with HTN and without CVD, did not led to vein dilation, but was associated with flow velocity and PVP decrease. By therapy’s end, most of venous hemodynamic parameters, including PVP, were identical in the studied groups.

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Optimal and Individualized Pneumatic Calf Compression Pressure using Vekroosan to Improve Femoral Venous Flow Velocity in Patients with Severe Post Thrombotic Syndrome: Case Reports and Literature Review

Journal of Thrombosis and Circulation Open Access ◽

10.4172/2572-9462-3-119 ◽

2017 ◽

Vol 03 (01) ◽

Author(s):

Ramakrishna R ◽

Alexander W

Keyword(s):

Literature Review ◽

Flow Velocity ◽

Case Reports ◽

Compression Pressure ◽

Venous Flow ◽

Post Thrombotic Syndrome ◽

Calf Compression

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Abstract 2690: Should We Classify Impaired Relaxation Pattern With Elevated E/e’ As Grade 1 Diastolic Dysfunction?

Circulation ◽

10.1161/circ.116.suppl_16.ii_596-b ◽

2007 ◽

Vol 116 (suppl_16) ◽

Author(s):

Un-jung Choi ◽

Hong-Seok Lim ◽

Soo-Jin Kang ◽

Jung-Won Hwang ◽

Byoung-Joo Choi ◽

...

Keyword(s):

Diastolic Dysfunction ◽

Flow Velocity ◽

Tissue Doppler ◽

Left Ventricular ◽

Doppler Imaging ◽

Transmitral Flow ◽

Venous Flow ◽

Mitral Annular Velocity ◽

Echocardiographic Measurement ◽

Ventricular Filling Pressure

Purpose : Impaired relaxation pattern (grade 1 diastolic dysfunction) by Doppler echocardiography is known to reflect preserved left ventricular filling pressure (LVFP), while increased ratio of early diastolic transmitral flow velocity to mitral annular velocity (E/E’) indicated elevated LVFP. We evaluated the characteristics of impaired relaxation pattern with elevated E/E’ ratio. Methods : Eighty-eight patients (mean age 63 ± 11, 59 males) who had coronary artery disease with impaired relaxation pattern (E/A < 1) were enrolled. Echocardiography including tissue Doppler imaging (TDI) was performed. All patients underwent cardiac catheterization to investigate LV pre-A pressure (LVP pre-A ) within 6 hours after echocardiographic measurement. Patients were divided into subjects with E/E’ < 10 (n = 71) and E/E’ ≥ 10 (n = 17). Results : LVP pre-A was well correlated with echocardiographic Doppler and hemodynamic parameters (E/E’, r = 0.536, p < 0.001; LA volume, r = 0.295, p = 0.008; EF, r = -0.234, p = 0.028). Forty (45% of total) patients had high LVFP, defined as LVP pre-A ≥15 mmHg. Patients with E/E’ ≥10 had a significantly higher incidence of high LVFP, when compared to patients with E/E’ < 10 (88% vs 35%, p < 0.001). LA volume and LVP pre-A were significantly increased and EF was decreased in patients with E/E’ ≥ 10 (table 1 ). However, there were no significant differences of parameters derived from transmitral inflow and transpulmonary venous flow between two groups. Conclusions : In patients with impaired relaxation pattern, elevated E/E’ has related to elevation of LVFP, regardless of transmitral inflow and transpulmonary indices. Therefore, impaired relaxation pattern with elevated ratio of early diastolic transmitral flow velocity to mitral annular velocity (E/E’) may have been considered as another grade of diastolic dysfunction. Table 1

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The risk of lower-limb superficial vein thrombosis relative to lower-limb venous thrombotic events is not increased in winter months

Phlebology The Journal of Venous Disease ◽

10.1177/0268355519896729 ◽

2020 ◽

Vol 35 (7) ◽

pp. 533-537

Author(s):

Samir Henni ◽

Pierre Ramondou ◽

Guillaume Duval ◽

Jean Picquet ◽

Georges Leftheriotis ◽

...

Keyword(s):

Venous Thrombosis ◽

Deep Venous Thrombosis ◽

Lower Limb ◽

Homogeneous Distribution ◽

Superficial Vein ◽

Chi Square ◽

Venous Flow ◽

Vein Thrombosis ◽

Superficial Vein Thrombosis ◽

Chi Square Test

Objectives Ambient temperature (that impacts differently venous flow in superficial and deep veins) could have a different effect on the risk of superficial and deep venous thrombosis. We searched for a trimestral variation of the risk of superficial venous thrombosis among all lower-limb thrombotic events (lower-limb thrombotic events = superficial venous thrombosis + deep venous thrombosis). Methods We retrospectively analyzed the results of venous ultrasound investigations performed among 11,739 patients (aged 67 ± 19 years old, 56.1% males) referred for suspected lower-limb thrombotic events over a 12-year period. Chi-square test was used to compare the superficial venous thrombosis/lower-limb thrombotic events ratio observed by trimesters to a homogeneous distribution. Results The proportion of lower-limb thrombotic events were 30.7%, 28.8%, 31.1%, and 31.4% (Chi2: 0.133; p = 0.987) of total investigations, while that of superficial venous thrombosis among all lower-limb venous thrombotic events were 27.2%, 30.0%, 31.4%, and 31.0%, for the first, second, third, and fourth trimesters respectively (Chi2: 0.357; p: 0.949). Conclusion No trimestral variation of the superficial venous thrombosis/lower-limb venous thrombotic events ratio was observed.

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